<?xml version="1.0" encoding="UTF-8"?>

<Bundle xmlns="http://hl7.org/fhir">
  <id value="BreastResectionDocument"/>
  <identifier>
    <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
    <value value="E_25_002"/>
  </identifier>
  <type value="document"/>
  <timestamp value="2025-02-10T17:00:00+01:00"/>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Composition/BreastResectionComposition"/>
    <resource>
      <Composition>
        <id value="BreastResectionComposition"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Composition_BreastResectionComposition"> </a><p class="res-header-id"><b>Generated Narrative: Composition BreastResectionComposition</b></p><a name="BreastResectionComposition"> </a><a name="hcBreastResectionComposition"> </a><p><b>identifier</b>: Accession ID/PATH-COMP-2025-210</p><p><b>status</b>: Final</p><p><b>type</b>: <span title="Codes:{http://ihe-d.de/CodeSystems/IHEXDStypeCode PATH}, {http://snomed.info/sct 371528001}">Pathology report (record artifact)</span></p><p><b>encounter</b>: <a href="Encounter-BreastResectionEncounter.html">Encounter: identifier = http://example.hospital.de/encounters#E_25_210; status = finished; class = IMP (IMP)</a></p><p><b>date</b>: 2025-02-10 17:00:00+0100</p><p><b>author</b>: <a href="Organization-PathologyLabOrganization.html">Institut für Pathologie</a></p><p><b>title</b>: Pathologisch-Anatomische Begutachtung - Makroskopische Beurteilung (BET)</p><h3>Attesters</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Mode</b></td><td><b>Party</b></td></tr><tr><td style="display: none">*</td><td>Legal</td><td><a href="Organization-PathologyLabOrganization.html">Organization Institut für Pathologie</a></td></tr></table><p><b>custodian</b>: <a href="Organization-PathologyLabOrganization.html">Organization Institut für Pathologie</a></p><h3>Events</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Detail</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode PATREPE}">pathology report entry task</span></td><td><a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></td></tr></table></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="ACSN"/>
              <display value="Accession ID"/>
            </coding>
          </type>
          <system value="http://example.hospital.de/pathology-reports"/>
          <value value="PATH-COMP-2025-210"/>
        </identifier>
        <status value="final"/>
        <type>
          <coding>
            <system value="http://ihe-d.de/CodeSystems/IHEXDStypeCode"/>
            <code value="PATH"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371528001"/>
            <display value="Pathology report (record artifact)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
          <display value="Sabine Becker, geb. 15.03.1971 (PAT-2025-105)"/>
        </subject>
        <encounter>
          <reference value="Encounter/BreastResectionEncounter"/>
        </encounter>
        <date value="2025-02-10T17:00:00+01:00"/>
        <author>
          <reference value="Organization/PathologyLabOrganization"/>
          <display value="Institut für Pathologie"/>
        </author>
        <title value="Pathologisch-Anatomische Begutachtung - Makroskopische Beurteilung (BET)"/>
        <attester>
          <mode value="legal"/>
          <party>
            <reference value="Organization/PathologyLabOrganization"/>
          </party>
        </attester>
        <custodian>
          <reference value="Organization/PathologyLabOrganization"/>
        </custodian>
        <event>
          <code>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/>
              <code value="PATREPE"/>
            </coding>
          </code>
          <detail>
            <reference value="ServiceRequest/BreastResectionReportRequest"/>
          </detail>
        </event>
        <section>
          <title value="Pathologiebefundbericht"/>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="11526-1"/>
              <display value="Pathology study"/>
            </coding>
          </code>
          <text>
            <status value="additional"/><div xmlns="http://www.w3.org/1999/xhtml"><h3>Klinische Angaben</h3><p>Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links indiziert. Drahthäkchenmarkierung. Keine neoadjuvante Therapie. Ersterkrankung. Keine bekannte genetische Prädisposition. Präparateradiographie beigelegt.</p><h3>Material</h3><p>BET-Exzisionspräparat Mamma links, mit Haut, Drahthäkchen in situ</p><h3>Makroskopie</h3><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>Größe</td><td>42 × 35 × 18 mm</td></tr><tr><td>Gewicht</td><td>10 g</td></tr><tr><td>Quadrant</td><td>Unterer äußerer Quadrant</td></tr><tr><td>Zifferblatt</td><td>5 Uhr</td></tr><tr><td>Abstand Mamille</td><td>50 mm</td></tr><tr><td>Lamellierung</td><td>8 Scheiben à 5 mm</td></tr><tr><td>Schnittfläche</td><td>Grau-weißlich, derber Herdbefund zentral in Scheibe III–V, ca. 18 mm</td></tr><tr><td>Paraffinblöcke</td><td>7</td></tr></tbody></table><h3>Mikroskopie</h3><p>Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Zentrale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.</p><h3>Diagnose</h3><p>Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c</p><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>ICD-10</td><td>C50.5</td></tr><tr><td>ICD-O-3 Morphologie</td><td>M8500/3</td></tr><tr><td>Operatives Verfahren</td><td>BET (brusterhaltende Therapie)</td></tr><tr><td>Seitenlokalisation</td><td>Links</td></tr><tr><td>Fokalität</td><td>Unifokal</td></tr><tr><td>Max. Durchmesser invasiv</td><td>18 mm</td></tr><tr><td>Max. Gesamtdurchmesser</td><td>22 mm</td></tr><tr><td>Nottingham-Grad</td><td>Grad 2 (Score 6: Tubuli 3, Pleomorphie 2, Mitosen 1)</td></tr><tr><td>Assoziiertes DCIS</td><td>Vorhanden, ohne extensive intraduktale Komponente (EIC), intermediärer Kerngrad, kribriform, zentrale Komedo-Nekrosen</td></tr><tr><td>Tumorausdehnung</td><td>Auf Brustdrüse beschränkt</td></tr><tr><td>pT-Kategorie</td><td>pT1c</td></tr></tbody></table><h4>Resektionsränder</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>RR-Status invasiv</td><td>Nicht befallen (R0)</td></tr><tr><td>Nächster tumorfreier RR</td><td>Posterior</td></tr><tr><td>Mindestabstand invasiv</td><td>5 mm</td></tr><tr><td>RR-Status DCIS</td><td>Nicht befallen</td></tr><tr><td>Mindestabstand DCIS</td><td>3 mm</td></tr></tbody></table><h4>Biomarker</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>ER</td><td>Positiv (90%, stark)</td></tr><tr><td>PR</td><td>Positiv (60%, mäßig)</td></tr><tr><td>HER2 (IHC)</td><td>1+</td></tr><tr><td>HER2 (ISH)</td><td>Nicht amplifiziert</td></tr><tr><td>HER2-Gesamtstatus</td><td>Negativ</td></tr><tr><td>Ki-67</td><td>15%</td></tr></tbody></table><h4>Weitere Befunde</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>Lymphgefäßinvasion</td><td>Nicht nachgewiesen</td></tr><tr><td>Mikrokalzifikationen</td><td>In DCIS assoziiert</td></tr></tbody></table><p><b>Kommentar:</b> Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</p></div>
          </text>
          <entry>
            <reference value="DiagnosticReport/BreastResectionReport"/>
          </entry>
        </section>
      </Composition>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Patient/Patient4"/>
    <resource>
      <Patient>
        <id value="Patient4"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_Patient4"> </a><p class="res-header-id"><b>Generated Narrative: Patient Patient4</b></p><a name="Patient4"> </a><a name="hcPatient4"> </a><p style="border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</p><hr/></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/patient-ids"/>
          <value value="PAT-2025-105"/>
        </identifier>
        <name>
          <family value="Becker"/>
          <given value="Sabine"/>
        </name>
        <gender value="female"/>
        <birthDate value="1971-03-15"/>
      </Patient>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Organization/PathologyLabOrganization"/>
    <resource>
      <Organization>
        <id value="PathologyLabOrganization"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_PathologyLabOrganization"> </a><p class="res-header-id"><b>Generated Narrative: Organization PathologyLabOrganization</b></p><a name="PathologyLabOrganization"> </a><a name="hcPathologyLabOrganization"> </a><p><b>identifier</b>: <code>http://example.hospital.de/organization-ids</code>/ORG-PATH-001</p><p><b>name</b>: Institut für Pathologie</p></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/organization-ids"/>
          <value value="ORG-PATH-001"/>
        </identifier>
        <name value="Institut für Pathologie"/>
      </Organization>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Practitioner/PathologistPractitioner"/>
    <resource>
      <Practitioner>
        <id value="PathologistPractitioner"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Practitioner_PathologistPractitioner"> </a><p class="res-header-id"><b>Generated Narrative: Practitioner PathologistPractitioner</b></p><a name="PathologistPractitioner"> </a><a name="hcPathologistPractitioner"> </a><p><b>identifier</b>: <code>http://example.hospital.de/practitioner-ids</code>/PATH-001</p><p><b>name</b>: Elisabeth Hoffmann </p><h3>Qualifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 394595002}">Pathology</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/practitioner-ids"/>
          <value value="PATH-001"/>
        </identifier>
        <name>
          <family value="Hoffmann"/>
          <given value="Elisabeth"/>
          <prefix value="Dr."/>
        </name>
        <qualification>
          <code>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="394595002"/>
              <display value="Pathology"/>
            </coding>
          </code>
        </qualification>
      </Practitioner>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Practitioner/BreastSurgeonPractitioner"/>
    <resource>
      <Practitioner>
        <id value="BreastSurgeonPractitioner"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Practitioner_BreastSurgeonPractitioner"> </a><p class="res-header-id"><b>Generated Narrative: Practitioner BreastSurgeonPractitioner</b></p><a name="BreastSurgeonPractitioner"> </a><a name="hcBreastSurgeonPractitioner"> </a><p><b>identifier</b>: <code>http://example.hospital.de/practitioner-ids</code>/GYN-001</p><p><b>name</b>: Thomas Richter </p><h3>Qualifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 394586005}">Gynecology</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/practitioner-ids"/>
          <value value="GYN-001"/>
        </identifier>
        <name>
          <family value="Richter"/>
          <given value="Thomas"/>
          <prefix value="Prof. Dr."/>
        </name>
        <qualification>
          <code>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="394586005"/>
              <display value="Gynecology"/>
            </coding>
          </code>
        </qualification>
      </Practitioner>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Encounter/BreastResectionEncounter"/>
    <resource>
      <Encounter>
        <id value="BreastResectionEncounter"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Encounter_BreastResectionEncounter"> </a><p class="res-header-id"><b>Generated Narrative: Encounter BreastResectionEncounter</b></p><a name="BreastResectionEncounter"> </a><a name="hcBreastResectionEncounter"> </a><p><b>identifier</b>: <code>http://example.hospital.de/encounters</code>/E_25_210</p><p><b>status</b>: Finished</p><p><b>class</b>: [not stated]: IMP (IMP)</p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/encounters"/>
          <value value="E_25_210"/>
        </identifier>
        <status value="finished"/>
        <class>
          <code value="IMP"/>
        </class>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
      </Encounter>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Condition/BreastResectionDiagnosisConfirmed"/>
    <resource>
      <Condition>
        <id value="BreastResectionDiagnosisConfirmed"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/StructureDefinition/Diagnose|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_BreastResectionDiagnosisConfirmed"> </a><p class="res-header-id"><b>Generated Narrative: Condition BreastResectionDiagnosisConfirmed</b></p><a name="BreastResectionDiagnosisConfirmed"> </a><a name="hcBreastResectionDiagnosisConfirmed"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.molgen@2026.0.4&amp;canonical=https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/StructureDefinition/Diagnose">MII PR Diagnose Condition</a> version: 2026.0.0</p></div><p><b>clinicalStatus</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/condition-clinical active}">Active</span></p><p><b>verificationStatus</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/condition-ver-status confirmed}">Confirmed</span></p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/condition-category encounter-diagnosis}">Encounter Diagnosis</span></p><p><b>code</b>: <span title="Codes:{http://fhir.de/CodeSystem/bfarm/icd-10-gm C50.5}">Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>encounter</b>: <a href="Encounter-BreastResectionEncounter.html">Encounter: identifier = http://example.hospital.de/encounters#E_25_210; status = finished; class = IMP (IMP)</a></p><p><b>onset</b>: 2025-01-15</p><p><b>recordedDate</b>: 2025-02-05</p><p><b>note</b>: </p><blockquote><div><p>Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links indiziert.</p>
</div></blockquote></div>
        </text>
        <clinicalStatus>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/condition-clinical"/>
            <code value="active"/>
          </coding>
        </clinicalStatus>
        <verificationStatus>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/condition-ver-status"/>
            <code value="confirmed"/>
          </coding>
        </verificationStatus>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/condition-category"/>
            <code value="encounter-diagnosis"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://fhir.de/CodeSystem/bfarm/icd-10-gm"/>
            <version value="2025"/>
            <code value="C50.5"/>
            <display value="Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <encounter>
          <reference value="Encounter/BreastResectionEncounter"/>
        </encounter>
        <onsetDateTime value="2025-01-15"/>
        <recordedDate value="2025-02-05"/>
        <note>
          <text value="Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links indiziert."/>
        </note>
      </Condition>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/ServiceRequest/BreastResectionReportRequest"/>
    <resource>
      <ServiceRequest>
        <id value="BreastResectionReportRequest"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-service-request|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="ServiceRequest_BreastResectionReportRequest"> </a><p class="res-header-id"><b>Generated Narrative: ServiceRequest BreastResectionReportRequest</b></p><a name="BreastResectionReportRequest"> </a><a name="hcBreastResectionReportRequest"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-service-request">MII PR Patho Service Request</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/PATH-RPT-2025-210</p><p><b>status</b>: Completed</p><p><b>intent</b>: Order</p><p><b>category</b>: <span title="Codes:{http://snomed.info/sct 726007}">Pathology consultation, comprehensive, records and specimen with report (procedure)</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 60568-3}">Pathology synoptic report</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>encounter</b>: <a href="Encounter-BreastResectionEncounter.html">Encounter: identifier = http://example.hospital.de/encounters#E_25_210; status = finished; class = IMP (IMP)</a></p><p><b>requester</b>: <a href="Practitioner-BreastSurgeonPractitioner.html">Practitioner Thomas Richter </a></p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>reasonCode</b>: <span title="Codes:{http://snomed.info/sct 254837009}">Malignant neoplasm of breast (disorder)</span></p><p><b>supportingInfo</b>: </p><ul><li><a href="Condition-BreastResectionDiagnosisConfirmed.html">Condition Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse</a></li><li><a href="DiagnosticReport-BreastResectionImagingReport.html">Diagnostic Report for 'MG Breast Screening' for '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href="Observation-BreastResectionCancerHistory.html">Observation Personal history of primary malignant neoplasm of breast (situation)</a></li><li><a href="Observation-BreastResectionPriorTherapy.html">Observation Cancer treatment --preoperative</a></li><li><a href="Observation-BreastResectionRadiologicalExtent.html">Observation Lesion size, largest dimension (observable entity)</a></li><li><a href="Observation-BreastResectionSpecimenMarking.html">Observation Insertion of marker into breast using X-ray guidance (procedure)</a></li><li><a href="Observation-BreastResectionSpecimenRadiographyClinical.html">Observation 80865008|Specimen mammography|:363702006|Has focus|=185008008|Medical reports sent|</a></li><li><a href="Observation-BreastResectionGeneticPredisposition.html">Observation Diathesis, function (observable entity)</a></li><li><a href="Observation-BreastResectionMacroQuadrant.html">Observation Quadrant Breast</a></li><li><a href="Observation-BreastResectionMacroClock.html">Observation Radial position in breast [Angle] in Breast cancer specimen</a></li><li><a href="Observation-BreastResectionMacroDistanceNipple.html">Observation Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)</a></li><li><a href="Observation-CoreNeedleBiopsyInterpretation.html">Observation Screening interpretation (observable entity)</a></li></ul><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="PLAC"/>
              <display value="Placer Identifier"/>
            </coding>
          </type>
          <system value="http://example.hospital.de/serviceRequest"/>
          <value value="PATH-RPT-2025-210"/>
        </identifier>
        <status value="completed"/>
        <intent value="order"/>
        <category>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="726007"/>
            <display value="Pathology consultation, comprehensive, records and specimen with report (procedure)"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="60568-3"/>
            <display value="Pathology synoptic report"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <encounter>
          <reference value="Encounter/BreastResectionEncounter"/>
        </encounter>
        <requester>
          <reference value="Practitioner/BreastSurgeonPractitioner"/>
        </requester>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <reasonCode>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="254837009"/>
            <display value="Malignant neoplasm of breast (disorder)"/>
          </coding>
        </reasonCode>
        <supportingInfo>
          <reference value="Condition/BreastResectionDiagnosisConfirmed"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="DiagnosticReport/BreastResectionImagingReport"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionCancerHistory"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionPriorTherapy"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionRadiologicalExtent"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionSpecimenMarking"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionSpecimenRadiographyClinical"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionGeneticPredisposition"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionMacroQuadrant"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionMacroClock"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/BreastResectionMacroDistanceNipple"/>
        </supportingInfo>
        <supportingInfo>
          <reference value="Observation/CoreNeedleBiopsyInterpretation"/>
        </supportingInfo>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
      </ServiceRequest>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/DiagnosticReport/BreastResectionImagingReport"/>
    <resource>
      <DiagnosticReport>
        <id value="BreastResectionImagingReport"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_BreastResectionImagingReport"> </a><p class="res-header-id"><b>Generated Narrative: DiagnosticReport BreastResectionImagingReport</b></p><a name="BreastResectionImagingReport"> </a><a name="hcBreastResectionImagingReport"> </a><h2><span title="Codes:{http://loinc.org 24606-6}">MG Breast Screening</span> (<span title="Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 RAD}">Radiology</span>) </h2><table class="grid"><tr><td>Subject</td><td>Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</td></tr><tr><td>When For</td><td>2025-01-08</td></tr></table><p><b>Report Details</b></p><p>BI-RADS 4b: Herdbefund linke Brust, unterer äußerer Quadrant, 5 Uhr, 5 cm von Mamille. Radiologische Ausdehnung ca. 15 mm. Mammografie und Ultraschall. Indikation zur BET.</p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/v2-0074"/>
            <code value="RAD"/>
            <display value="Radiology"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="24606-6"/>
            <display value="MG Breast Screening"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-01-08"/>
        <conclusion value="BI-RADS 4b: Herdbefund linke Brust, unterer äußerer Quadrant, 5 Uhr, 5 cm von Mamille. Radiologische Ausdehnung ca. 15 mm. Mammografie und Ultraschall. Indikation zur BET."/>
      </DiagnosticReport>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionCancerHistory"/>
    <resource>
      <Observation>
        <id value="BreastResectionCancerHistory"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionCancerHistory"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionCancerHistory</b></p><a name="BreastResectionCancerHistory"> </a><a name="hcBreastResectionCancerHistory"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 415076002}">Brustkrebsvorgeschichte</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:">Ersterkrankung</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="415076002"/>
            <display value="Personal history of primary malignant neoplasm of breast (situation)"/>
          </coding>
          <text value="Brustkrebsvorgeschichte"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <text value="Ersterkrankung"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionPriorTherapy"/>
    <resource>
      <Observation>
        <id value="BreastResectionPriorTherapy"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionPriorTherapy"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionPriorTherapy</b></p><a name="BreastResectionPriorTherapy"> </a><a name="hcBreastResectionPriorTherapy"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://loinc.org 81167-9}">Vorchirurgische Therapie bei invasivem Karzinom</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 373067005}">Keine neoadjuvante Therapie</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="81167-9"/>
            <display value="Cancer treatment --preoperative"/>
          </coding>
          <text value="Vorchirurgische Therapie bei invasivem Karzinom"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="373067005"/>
            <display value="No (qualifier value)"/>
          </coding>
          <text value="Keine neoadjuvante Therapie"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionRadiologicalExtent"/>
    <resource>
      <Observation>
        <id value="BreastResectionRadiologicalExtent"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionRadiologicalExtent"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionRadiologicalExtent</b></p><a name="BreastResectionRadiologicalExtent"> </a><a name="hcBreastResectionRadiologicalExtent"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 396361002}">Radiologische Ausdehnung</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: 15 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="396361002"/>
            <display value="Lesion size, largest dimension (observable entity)"/>
          </coding>
          <text value="Radiologische Ausdehnung"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <valueQuantity>
          <value value="15"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionSpecimenMarking"/>
    <resource>
      <Observation>
        <id value="BreastResectionSpecimenMarking"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionSpecimenMarking"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionSpecimenMarking</b></p><a name="BreastResectionSpecimenMarking"> </a><a name="hcBreastResectionSpecimenMarking"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 836381000000102}">Befundmarkierung</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:">Drahthäkchen</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="836381000000102"/>
            <display value="Insertion of marker into breast using X-ray guidance (procedure)"/>
          </coding>
          <text value="Befundmarkierung"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <text value="Drahthäkchen"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionSpecimenRadiographyClinical"/>
    <resource>
      <Observation>
        <id value="BreastResectionSpecimenRadiographyClinical"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionSpecimenRadiographyClinical"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionSpecimenRadiographyClinical</b></p><a name="BreastResectionSpecimenRadiographyClinical"> </a><a name="hcBreastResectionSpecimenRadiographyClinical"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 80865008:363702006=185008008}">Präparateradiographie beigelegt</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 52101004}">Ja, beigelegt</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="80865008:363702006=185008008"/>
            <display value="80865008|Specimen mammography|:363702006|Has focus|=185008008|Medical reports sent|"/>
          </coding>
          <text value="Präparateradiographie beigelegt"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="52101004"/>
            <display value="Present (qualifier value)"/>
          </coding>
          <text value="Ja, beigelegt"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionGeneticPredisposition"/>
    <resource>
      <Observation>
        <id value="BreastResectionGeneticPredisposition"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionGeneticPredisposition"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionGeneticPredisposition</b></p><a name="BreastResectionGeneticPredisposition"> </a><a name="hcBreastResectionGeneticPredisposition"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 76522002}">Genetische Prädisposition</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 261665006}">Nicht bekannt</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76522002"/>
            <display value="Diathesis, function (observable entity)"/>
          </coding>
          <text value="Genetische Prädisposition"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="261665006"/>
            <display value="Unknown (qualifier value)"/>
          </coding>
          <text value="Nicht bekannt"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/DiagnosticReport/BreastResectionReport"/>
    <resource>
      <DiagnosticReport>
        <id value="BreastResectionReport"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-report|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_BreastResectionReport"> </a><p class="res-header-id"><b>Generated Narrative: DiagnosticReport BreastResectionReport</b></p><a name="BreastResectionReport"> </a><a name="hcBreastResectionReport"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-report">MII PR Patho Report</a> version: 2026.0.0</p></div><h2><span title="Codes:{http://loinc.org 60568-3}">Pathology Synoptic report</span> (<span title="Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 SP}">Surgical Pathology</span>) </h2><table class="grid"><tr><td>Subject</td><td>Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</td></tr><tr><td>When For</td><td>2025-02-10 14:00:00+0100</td></tr><tr><td>Reported</td><td>2025-02-10 17:00:00+0100</td></tr><tr><td>Performer</td><td> <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></td></tr><tr><td>Identifier</td><td> Accession ID/E_25_210</td></tr></table><p><b>Report Details</b></p><table class="grid"><tr><td><b>Code</b></td><td><b>Value</b></td><td><b>Flags</b></td><td><b>When For</b></td></tr><tr><td><a href="Observation-BreastResectionMacroscopicGrouper.html"><span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></a> (<span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span>)</td><td/><td>Final</td><td>2025-02-06 08:30:00+0100</td></tr><tr><td><a href="Observation-BreastResectionDiagnosticConclusionGrouper.html"><span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></a></td><td/><td>Final</td><td>2025-02-10</td></tr></table><p>Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c, Nottingham Grad 2 (Score 6: Tubuli 3, Kernpleomorphie 2, Mitosen 1). Begleitendes DCIS, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen. Alle Resektionsränder tumorfrei (invasiv 5 mm, DCIS 3 mm). Keine LVI. ER+ (90%), PR+ (60%), HER2 1+ (nicht amplifiziert), Ki-67 15%.</p></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="ACSN"/>
              <display value="Accession ID"/>
            </coding>
          </type>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </identifier>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/v2-0074"/>
            <code value="SP"/>
            <display value="Surgical Pathology"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="60568-3"/>
            <display value="Pathology Synoptic report"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10T14:00:00+01:00"/>
        <issued value="2025-02-10T17:00:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenBlock02"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenBlock03"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenBlock04"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenBlock05"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenBlock06"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE02"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideER01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlidePR01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHER2IHC01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideKi67-01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideCK18-01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlidep40-01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideECad-01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideBlock02-HE01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideBlock02-HE02"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideRR-Superior-HE01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideRR-Inferior-HE01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideRR-Medial-HE01"/>
        </specimen>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideRR-Lateral-HE01"/>
        </specimen>
        <result>
          <reference value="Observation/BreastResectionMacroscopicGrouper"/>
        </result>
        <result>
          <reference value="Observation/BreastResectionDiagnosticConclusionGrouper"/>
        </result>
        <conclusion value="Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c, Nottingham Grad 2 (Score 6: Tubuli 3, Kernpleomorphie 2, Mitosen 1). Begleitendes DCIS, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen. Alle Resektionsränder tumorfrei (invasiv 5 mm, DCIS 3 mm). Keine LVI. ER+ (90%), PR+ (60%), HER2 1+ (nicht amplifiziert), Ki-67 15%."/>
      </DiagnosticReport>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenPart"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenPart"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenPart"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenPart</b></p><a name="BreastResectionSpecimenPart"> </a><a name="hcBreastResectionSpecimenPart"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/OP25_210_A, Filler Identifier/E_25_210_A</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 397199005}">Specimen from breast obtained by excision (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>request</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collector</b></td><td><b>Collected[x]</b></td><td><b>Method</b></td><td><b>BodySite</b></td></tr><tr><td style="display: none">*</td><td><a href="Practitioner-BreastSurgeonPractitioner.html">Practitioner Thomas Richter </a></td><td>2025-02-05 10:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 237371007}">Wide local excision of breast lesion (procedure)</span></td><td><span title="Codes:{http://snomed.info/sct 33564002}">Structure of lower outer quadrant of breast (body structure)</span></td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 434746001}">Specimen vial (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 434162003}">Neutral buffered formalin (substance)</span></td></tr></table><p><b>note</b>: </p><blockquote><div><p>BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</p>
</div></blockquote></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="PLAC"/>
            </coding>
          </type>
          <system value="https://senologie.example-hospital.de/fhir/specimen/placer"/>
          <value value="OP25_210_A"/>
        </identifier>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="FILL"/>
            </coding>
          </type>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="397199005"/>
            <display value="Specimen from breast obtained by excision (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <request>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </request>
        <collection>
          <collector>
            <reference value="Practitioner/BreastSurgeonPractitioner"/>
          </collector>
          <collectedDateTime value="2025-02-05T10:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="237371007"/>
              <display value="Wide local excision of breast lesion (procedure)"/>
            </coding>
          </method>
          <bodySite>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="33564002"/>
              <display value="Structure of lower outer quadrant of breast (body structure)"/>
            </coding>
          </bodySite>
        </collection>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434746001"/>
              <display value="Specimen vial (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434162003"/>
              <display value="Neutral buffered formalin (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
        <note>
          <text value="BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ."/>
        </note>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock01</b></p><a name="BreastResectionSpecimenBlock01"> </a><a name="hcBreastResectionSpecimenBlock01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe III</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:00:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe III"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock02"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock02"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock02</b></p><a name="BreastResectionSpecimenBlock02"> </a><a name="hcBreastResectionSpecimenBlock02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_2</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:10:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe V</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:10:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_2"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:10:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe V"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:10:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock03"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock03"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock03"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock03</b></p><a name="BreastResectionSpecimenBlock03"> </a><a name="hcBreastResectionSpecimenBlock03"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_3</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:20:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Resektionsrand superior</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:20:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_3"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:20:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Resektionsrand superior"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:20:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock04"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock04"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock04"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock04</b></p><a name="BreastResectionSpecimenBlock04"> </a><a name="hcBreastResectionSpecimenBlock04"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_4</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:25:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Resektionsrand inferior</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:25:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_4"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:25:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Resektionsrand inferior"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:25:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock05"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock05"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock05"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock05</b></p><a name="BreastResectionSpecimenBlock05"> </a><a name="hcBreastResectionSpecimenBlock05"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_5</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Resektionsrand medial (Scheibe I)</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:30:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_5"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Resektionsrand medial (Scheibe I)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:30:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock06"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock06"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock06"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock06</b></p><a name="BreastResectionSpecimenBlock06"> </a><a name="hcBreastResectionSpecimenBlock06"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_6</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:35:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Resektionsrand lateral (Scheibe VIII)</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:35:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_6"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:35:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Resektionsrand lateral (Scheibe VIII)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:35:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenBlock07"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenBlock07"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenBlock07"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenBlock07</b></p><a name="BreastResectionSpecimenBlock07"> </a><a name="hcBreastResectionSpecimenBlock07"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_7</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:40:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Resektionsrand posterior</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:40:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_7"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:40:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Zuschnitt und Paraffineinbettung - Resektionsrand posterior"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:40:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideHE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideHE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideHE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideHE01</b></p><a name="BreastResectionSpecimenSlideHE01"> </a><a name="hcBreastResectionSpecimenSlideHE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 1)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideHE02"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideHE02"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideHE02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideHE02</b></p><a name="BreastResectionSpecimenSlideHE02"> </a><a name="hcBreastResectionSpecimenSlideHE02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_HE_02"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 2)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideER01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideER01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideER01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideER01</b></p><a name="BreastResectionSpecimenSlideER01"> </a><a name="hcBreastResectionSpecimenSlideER01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_ER_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: ER-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstanceER.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_ER_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="ER-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstanceER"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlidePR01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlidePR01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlidePR01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlidePR01</b></p><a name="BreastResectionSpecimenSlidePR01"> </a><a name="hcBreastResectionSpecimenSlidePR01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_PR_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:35:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:35:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: PR-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstancePR.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:05:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_PR_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:35:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:35:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="PR-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstancePR"/>
          </additive>
          <timeDateTime value="2025-02-06T10:05:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideHER2IHC01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideHER2IHC01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideHER2IHC01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideHER2IHC01</b></p><a name="BreastResectionSpecimenSlideHER2IHC01"> </a><a name="hcBreastResectionSpecimenSlideHER2IHC01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_HER2IHC_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:40:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:40:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HER2-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 433114000}">Human epidermal growth factor receptor 2 gene detection by immunohistochemistry (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstanceHER2IHC.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:30:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_HER2IHC_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:40:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:40:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HER2-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433114000"/>
              <display value="Human epidermal growth factor receptor 2 gene detection by immunohistochemistry (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstanceHER2IHC"/>
          </additive>
          <timeDateTime value="2025-02-06T10:30:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideKi67-01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideKi67-01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideKi67-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideKi67-01</b></p><a name="BreastResectionSpecimenSlideKi67-01"> </a><a name="hcBreastResectionSpecimenSlideKi67-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_Ki67_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:45:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:45:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Ki-67 Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstanceKi67.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:10:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_Ki67_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:45:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:45:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Ki-67 Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstanceKi67"/>
          </additive>
          <timeDateTime value="2025-02-06T10:10:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideCK18-01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideCK18-01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideCK18-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideCK18-01</b></p><a name="BreastResectionSpecimenSlideCK18-01"> </a><a name="hcBreastResectionSpecimenSlideCK18-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_CK18_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:50:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:50:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: CK18-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstanceCK18.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:35:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_CK18_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:50:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:50:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="CK18-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstanceCK18"/>
          </additive>
          <timeDateTime value="2025-02-06T10:35:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlidep40-01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlidep40-01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlidep40-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlidep40-01</b></p><a name="BreastResectionSpecimenSlidep40-01"> </a><a name="hcBreastResectionSpecimenSlidep40-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_p40_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:55:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:55:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: p40-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstancep40.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:40:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_p40_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:55:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:55:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="p40-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstancep40"/>
          </additive>
          <timeDateTime value="2025-02-06T10:40:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideECad-01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideECad-01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideECad-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideECad-01</b></p><a name="BreastResectionSpecimenSlideECad-01"> </a><a name="hcBreastResectionSpecimenSlideECad-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_1_1_ECad_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 10:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: E-Cadherin-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-BreastResectionSubstanceECadherin.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:45:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_1_1_ECad_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T10:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="E-Cadherin-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>
            <reference value="Substance/BreastResectionSubstanceECadherin"/>
          </additive>
          <timeDateTime value="2025-02-06T10:45:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideBlock02-HE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideBlock02-HE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideBlock02-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideBlock02-HE01</b></p><a name="BreastResectionSpecimenSlideBlock02-HE01"> </a><a name="hcBreastResectionSpecimenSlideBlock02-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_2_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:20:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:20:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:35:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_2_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock02"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:20:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 1)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:20:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:35:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideBlock02-HE02"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideBlock02-HE02"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideBlock02-HE02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideBlock02-HE02</b></p><a name="BreastResectionSpecimenSlideBlock02-HE02"> </a><a name="hcBreastResectionSpecimenSlideBlock02-HE02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_2_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:20:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:20:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:35:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_2_1_HE_02"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock02"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:20:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 2)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:20:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:35:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideRR-Superior-HE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideRR-Superior-HE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideRR-Superior-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideRR-Superior-HE01</b></p><a name="BreastResectionSpecimenSlideRR-Superior-HE01"> </a><a name="hcBreastResectionSpecimenSlideRR-Superior-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_3_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock03.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_3; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:25:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:25:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:40:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_3_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock03"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:25:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:25:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:40:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideRR-Inferior-HE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideRR-Inferior-HE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideRR-Inferior-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideRR-Inferior-HE01</b></p><a name="BreastResectionSpecimenSlideRR-Inferior-HE01"> </a><a name="hcBreastResectionSpecimenSlideRR-Inferior-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_4_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock04.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_4; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:28:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:28:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:43:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_4_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock04"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:28:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:28:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:43:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideRR-Medial-HE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideRR-Medial-HE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideRR-Medial-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideRR-Medial-HE01</b></p><a name="BreastResectionSpecimenSlideRR-Medial-HE01"> </a><a name="hcBreastResectionSpecimenSlideRR-Medial-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_5_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock05.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_5; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:31:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:31:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:46:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_5_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock05"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:31:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:31:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:46:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideRR-Lateral-HE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideRR-Lateral-HE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideRR-Lateral-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideRR-Lateral-HE01</b></p><a name="BreastResectionSpecimenSlideRR-Lateral-HE01"> </a><a name="hcBreastResectionSpecimenSlideRR-Lateral-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_6_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock06.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_6; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:34:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:34:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:49:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_6_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock06"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:34:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:34:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:49:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Specimen/BreastResectionSpecimenSlideRR-Posterior-HE01"/>
    <resource>
      <Specimen>
        <id value="BreastResectionSpecimenSlideRR-Posterior-HE01"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_BreastResectionSpecimenSlideRR-Posterior-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen BreastResectionSpecimenSlideRR-Posterior-HE01</b></p><a name="BreastResectionSpecimenSlideRR-Posterior-HE01"> </a><a name="hcBreastResectionSpecimenSlideRR-Posterior-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210_A_7_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_210</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-BreastResectionSpecimenBlock07.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_7; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:37:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:37:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:52:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210_A_7_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_210"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>
          <reference value="Specimen/BreastResectionSpecimenBlock07"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:37:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:37:00+01:00"/>
        </processing>
        <processing>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:52:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstanceER"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstanceER"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstanceER"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstanceER</b></p><a name="BreastResectionSubstanceER"> </a><a name="hcBreastResectionSubstanceER"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Estrogen Receptor (Dako Omnis)</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Estrogen Receptor (Dako Omnis)"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstancePR"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstancePR"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstancePR"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstancePR</b></p><a name="BreastResectionSubstancePR"> </a><a name="hcBreastResectionSubstancePR"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Progesterone Receptor (Dako Omnis)</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Progesterone Receptor (Dako Omnis)"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstanceHER2IHC"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstanceHER2IHC"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstanceHER2IHC"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstanceHER2IHC</b></p><a name="BreastResectionSubstanceHER2IHC"> </a><a name="hcBreastResectionSubstanceHER2IHC"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: VENTANA HER2 (4B5), Roche</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="VENTANA HER2 (4B5), Roche"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstanceKi67"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstanceKi67"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstanceKi67"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstanceKi67</b></p><a name="BreastResectionSubstanceKi67"> </a><a name="hcBreastResectionSubstanceKi67"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Ki-67 Antigen (Dako Omnis)</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Ki-67 Antigen (Dako Omnis)"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstanceCK18"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstanceCK18"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstanceCK18"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstanceCK18</b></p><a name="BreastResectionSubstanceCK18"> </a><a name="hcBreastResectionSubstanceCK18"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Cytokeratin 18 (DC10), Dako Omnis</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Cytokeratin 18 (DC10), Dako Omnis"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstancep40"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstancep40"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstancep40"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstancep40</b></p><a name="BreastResectionSubstancep40"> </a><a name="hcBreastResectionSubstancep40"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: p40 (BC28), Biocare Medical</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="p40 (BC28), Biocare Medical"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Substance/BreastResectionSubstanceECadherin"/>
    <resource>
      <Substance>
        <id value="BreastResectionSubstanceECadherin"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_BreastResectionSubstanceECadherin"> </a><p class="res-header-id"><b>Generated Narrative: Substance BreastResectionSubstanceECadherin</b></p><a name="BreastResectionSubstanceECadherin"> </a><a name="hcBreastResectionSubstanceECadherin"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: E-Cadherin (NCH-38), Dako Omnis</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="E-Cadherin (NCH-38), Dako Omnis"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroscopicGrouper"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroscopicGrouper"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-macroscopic-grouper|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroscopicGrouper"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroscopicGrouper</b></p><a name="BreastResectionMacroscopicGrouper"> </a><a name="hcBreastResectionMacroscopicGrouper"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-macroscopic-grouper">MII PR Patho Macroscopic Grouper</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>hasMember</b>: </p><ul><li><a href="Observation-BreastResectionMacroLength.html">Observation Specimen size.maximum dimension in Breast tumor</a></li><li><a href="Observation-BreastResectionMacroWidth.html">Observation Specimen size additional dimension 1 in Breast tumor</a></li><li><a href="Observation-BreastResectionMacroDepth.html">Observation Specimen size additional dimension 2 in Breast tumor</a></li><li><a href="Observation-BreastResectionMacroWeight.html">Observation Specimen wt Tiss Qn</a></li><li><a href="Observation-BreastResectionMacroQuadrant.html">Observation Quadrant Breast</a></li><li><a href="Observation-BreastResectionMacroClock.html">Observation Radial position in breast [Angle] in Breast cancer specimen</a></li><li><a href="Observation-BreastResectionMacroDistanceNipple.html">Observation Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)</a></li><li><a href="Observation-BreastResectionMacroBlockCount.html">Observation Number of paraffin embedded tissue blocks examined from excised specimen (observable entity)</a></li></ul><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <hasMember>
          <reference value="Observation/BreastResectionMacroLength"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroWidth"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroDepth"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroWeight"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroQuadrant"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroClock"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroDistanceNipple"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMacroBlockCount"/>
        </hasMember>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroLength"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroLength"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroLength"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroLength</b></p><a name="BreastResectionMacroLength"> </a><a name="hcBreastResectionMacroLength"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44629-4}">ProbeGröße1</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 42 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44629-4"/>
            <display value="Specimen size.maximum dimension in Breast tumor"/>
          </coding>
          <text value="ProbeGröße1"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="42"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroWidth"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroWidth"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroWidth"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroWidth</b></p><a name="BreastResectionMacroWidth"> </a><a name="hcBreastResectionMacroWidth"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44630-2}">ProbeGröße2</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 35 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44630-2"/>
            <display value="Specimen size additional dimension 1 in Breast tumor"/>
          </coding>
          <text value="ProbeGröße2"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="35"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroDepth"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroDepth"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroDepth"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroDepth</b></p><a name="BreastResectionMacroDepth"> </a><a name="hcBreastResectionMacroDepth"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44631-0}">ProbeGröße3</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 18 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44631-0"/>
            <display value="Specimen size additional dimension 2 in Breast tumor"/>
          </coding>
          <text value="ProbeGröße3"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="18"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroWeight"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroWeight"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroWeight"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroWeight</b></p><a name="BreastResectionMacroWeight"> </a><a name="hcBreastResectionMacroWeight"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 29638-4}">Gewicht der Probe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 10 g<span style="background: LightGoldenRodYellow"> (Details: UCUM  codeg = 'g')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="29638-4"/>
            <display value="Specimen wt Tiss Qn"/>
          </coding>
          <text value="Gewicht der Probe"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="10"/>
          <unit value="g"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="g"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroQuadrant"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroQuadrant"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroQuadrant"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroQuadrant</b></p><a name="BreastResectionMacroQuadrant"> </a><a name="hcBreastResectionMacroQuadrant"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 42799-7}">Quadrantenlokalisaion</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 33564002}">Unterer äußerer Quadrant</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="42799-7"/>
            <display value="Quadrant Breast"/>
          </coding>
          <text value="Quadrantenlokalisaion"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="33564002"/>
            <display value="Structure of lower outer quadrant of breast (body structure)"/>
          </coding>
          <text value="Unterer äußerer Quadrant"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroClock"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroClock"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroClock"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroClock</b></p><a name="BreastResectionMacroClock"> </a><a name="hcBreastResectionMacroClock"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85332-5}, {http://snomed.info/sct 3980001000004105}">Zifferblattlokalisation</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 5 o'clock<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{clock position} = '{clock position}')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85332-5"/>
            <display value="Radial position in breast [Angle] in Breast cancer specimen"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3980001000004105"/>
            <display value="Radial location of primary malignant neoplasm in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Zifferblattlokalisation"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="5"/>
          <unit value="o'clock"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{clock position}"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroDistanceNipple"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroDistanceNipple"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroDistanceNipple"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroDistanceNipple</b></p><a name="BreastResectionMacroDistanceNipple"> </a><a name="hcBreastResectionMacroDistanceNipple"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1240401000}">Abstand von der Mamille</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 50 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1240401000"/>
            <display value="Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Abstand von der Mamille"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="50"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMacroBlockCount"/>
    <resource>
      <Observation>
        <id value="BreastResectionMacroBlockCount"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMacroBlockCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMacroBlockCount</b></p><a name="BreastResectionMacroBlockCount"> </a><a name="hcBreastResectionMacroBlockCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 3100001000004109}">Anzahl Paraffinblöcke</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 6 Blöcke<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{blocks} = '{blocks}')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3100001000004109"/>
            <display value="Number of paraffin embedded tissue blocks examined from excised specimen (observable entity)"/>
          </coding>
          <text value="Anzahl Paraffinblöcke"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="6"/>
          <unit value="Blöcke"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{blocks}"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionDiagnosticConclusionGrouper"/>
    <resource>
      <Observation>
        <id value="BreastResectionDiagnosticConclusionGrouper"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-diagnostic-conclusion-grouper|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionDiagnosticConclusionGrouper"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionDiagnosticConclusionGrouper</b></p><a name="BreastResectionDiagnosticConclusionGrouper"> </a><a name="hcBreastResectionDiagnosticConclusionGrouper"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-diagnostic-conclusion-grouper">MII PR Patho Diagnostic Conclusion Grouper</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>hasMember</b>: </p><ul><li><a href="Observation-BreastResectionOperativeProcedure.html">Observation Surgery procedure</a></li><li><a href="Observation-BreastResectionMaterialType.html">Observation Specimen type</a></li><li><a href="Observation-BreastResectionLaterality.html">Observation Specimen laterality (observable entity)</a></li><li><a href="Observation-BreastResectionAttachedTissue.html">Observation Body structure included in specimen [Anatomy] in Specimen</a></li><li><a href="Observation-BreastResectionFocality.html">Observation Qualitative distribution of primary malignant neoplasm of breast in excised breast specimen (observable entity)</a></li><li><a href="Observation-BreastResectionMaxDiameterInvasive.html">Observation Inv comp size max dim BT</a></li><li><a href="Observation-BreastResectionMaxOverallDiameter.html">Observation Size.maximum dimension in Tumor</a></li><li><a href="Observation-BreastResectionHistologicalType.html">Observation Histo type BT</a></li><li><a href="Observation-BreastResectionMorphologyFreeText.html">Observation Histology type in Cancer specimen Narrative</a></li><li><a href="Observation-BreastResectionNottinghamGrade.html">Observation Nottingham combined grade of primary malignant neoplasm of breast (observable entity)</a></li><li><a href="Observation-BreastResectionNottinghamSummaryScore.html">Observation Nottingham total score of primary malignant neoplasm of breast (observable entity)</a></li><li><a href="Observation-BreastResectionMitosisCount.html">Observation Number of mitoses per 10 high power fields (observable entity)</a></li><li><a href="Observation-BreastResectionAssociatedDCIS.html">Observation DCIS intraduct ext Br ca spec Ql Micro</a></li><li><a href="Observation-BreastResectionDCISGrade.html">Observation Nuclear grade of ductal carcinoma in situ of breast (observable entity)</a></li><li><a href="Observation-BreastResectionDCISArchitecture.html">Observation Growth pattern of DCIS [Type] in Breast cancer specimen by Light microscopy</a></li><li><a href="Observation-BreastResectionDCISNecrosis.html">Observation DCIS necrosis [Type] in Breast cancer specimen by Light microscopy</a></li><li><a href="Observation-BreastResectionTumorExtent.html">Observation Adjacent structure invaded by tumor [Anatomy] in Breast cancer specimen by Light microscopy</a></li><li><a href="Observation-BreastResectionMarginStatusInvasive.html">Observation Margin involved BT</a></li><li><a href="Observation-BreastResectionClosestMargin.html">Observation IC uninv marg closest BT</a></li><li><a href="Observation-BreastResectionMinDistanceInvasive.html">Observation IC uninv marg dist closest BT</a></li><li><a href="Observation-BreastResectionMarginStatusNonInvasive.html">Observation Surgical margin DCIS involvement [Presence] in Breast cancer specimen by Light microscopy</a></li><li><a href="Observation-BreastResectionMinDistanceNonInvasive.html">Observation DCIS.uninv marg dist.closest BT</a></li><li><a href="Observation-BreastResectionLVI.html">Observation Lymph-vascular invasion Ca spec</a></li><li><a href="Observation-BreastResectionMicrocalcification.html">Observation Presence of microcalcification in excised breast specimen (observable entity)</a></li><li><a href="Observation-BreastResectionERStatus.html">Observation Estrogen receptor [Interpretation] in Tissue</a></li><li><a href="Observation-BreastResectionERPercentage.html">Observation Cells.estrogen receptor/cells in Breast cancer specimen by Immune stain</a></li><li><a href="Observation-BreastResectionERIntensity.html">Observation Estrogen receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain</a></li><li><a href="Observation-BreastResectionPRStatus.html">Observation Progesterone receptor [Interpretation] in Tissue</a></li><li><a href="Observation-BreastResectionPRPercentage.html">Observation Cells.progesterone receptor/cells in Breast cancer specimen by Immune stain</a></li><li><a href="Observation-BreastResectionPRIntensity.html">Observation Intensity of stain of progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)</a></li><li><a href="Observation-BreastResectionHER2IHC.html">Observation HER2 [Presence] in Breast cancer specimen by Immune stain</a></li><li><a href="Observation-BreastResectionHER2ISH.html">Observation Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by in situ hybridization (observable entity)</a></li><li><a href="Observation-BreastResectionHER2Overall.html">Observation HER2 [Interpretation] in Tissue</a></li><li><a href="Observation-BreastResectionKi67.html">Observation Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain</a></li><li><a href="Observation-BreastResectionPT.html">Observation pT category (observable entity)</a></li><li><a href="Observation-BreastResectionComment.html">Observation Pathology report comments [Interpretation] Narrative</a></li></ul><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <hasMember>
          <reference value="Observation/BreastResectionOperativeProcedure"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMaterialType"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionLaterality"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionAttachedTissue"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionFocality"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMaxDiameterInvasive"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMaxOverallDiameter"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionHistologicalType"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMorphologyFreeText"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionNottinghamGrade"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionNottinghamSummaryScore"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMitosisCount"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionAssociatedDCIS"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionDCISGrade"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionDCISArchitecture"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionDCISNecrosis"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionTumorExtent"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMarginStatusInvasive"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionClosestMargin"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMinDistanceInvasive"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMarginStatusNonInvasive"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMinDistanceNonInvasive"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionLVI"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionMicrocalcification"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionERStatus"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionERPercentage"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionERIntensity"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionPRStatus"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionPRPercentage"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionPRIntensity"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionHER2IHC"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionHER2ISH"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionHER2Overall"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionKi67"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionPT"/>
        </hasMember>
        <hasMember>
          <reference value="Observation/BreastResectionComment"/>
        </hasMember>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionOperativeProcedure"/>
    <resource>
      <Observation>
        <id value="BreastResectionOperativeProcedure"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionOperativeProcedure"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionOperativeProcedure</b></p><a name="BreastResectionOperativeProcedure"> </a><a name="hcBreastResectionOperativeProcedure"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 29306-8}, {http://snomed.info/sct 2620001000004108}">Operatives Verfahren</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 237371007}">Brusterhaltende Therapie (BET)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="29306-8"/>
            <display value="Surgery procedure"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2620001000004108"/>
            <display value="Specimen collection procedure (observable entity)"/>
          </coding>
          <text value="Operatives Verfahren"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="237371007"/>
            <display value="Wide local excision of breast lesion (procedure)"/>
          </coding>
          <text value="Brusterhaltende Therapie (BET)"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMaterialType"/>
    <resource>
      <Observation>
        <id value="BreastResectionMaterialType"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMaterialType"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMaterialType</b></p><a name="BreastResectionMaterialType"> </a><a name="hcBreastResectionMaterialType"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 66746-9}">Materialart</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 309546004}">Exzisionspräparat</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="66746-9"/>
            <display value="Specimen type"/>
          </coding>
          <text value="Materialart"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="309546004"/>
            <display value="Lumpectomy breast specimen (specimen)"/>
          </coding>
          <text value="Exzisionspräparat"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionLaterality"/>
    <resource>
      <Observation>
        <id value="BreastResectionLaterality"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionLaterality"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionLaterality</b></p><a name="BreastResectionLaterality"> </a><a name="hcBreastResectionLaterality"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 384727002}">Seitenlokalisation der Probe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 7771000}">Links</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="384727002"/>
            <display value="Specimen laterality (observable entity)"/>
          </coding>
          <text value="Seitenlokalisation der Probe"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="7771000"/>
            <display value="Left (qualifier value)"/>
          </coding>
          <text value="Links"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionAttachedTissue"/>
    <resource>
      <Observation>
        <id value="BreastResectionAttachedTissue"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionAttachedTissue"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionAttachedTissue</b></p><a name="BreastResectionAttachedTissue"> </a><a name="hcBreastResectionAttachedTissue"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85298-8}">Material/anhängendes Gewebe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 39937001}">Haut</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85298-8"/>
            <display value="Body structure included in specimen [Anatomy] in Specimen"/>
          </coding>
          <text value="Material/anhängendes Gewebe"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="39937001"/>
            <display value="Skin structure (body structure)"/>
          </coding>
          <text value="Haut"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionFocality"/>
    <resource>
      <Observation>
        <id value="BreastResectionFocality"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionFocality"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionFocality</b></p><a name="BreastResectionFocality"> </a><a name="hcBreastResectionFocality"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1157128007}">(Multi)fokalität</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">Unifokal</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1157128007"/>
            <display value="Qualitative distribution of primary malignant neoplasm of breast in excised breast specimen (observable entity)"/>
          </coding>
          <text value="(Multi)fokalität"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="Unifokal"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMaxDiameterInvasive"/>
    <resource>
      <Observation>
        <id value="BreastResectionMaxDiameterInvasive"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMaxDiameterInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMaxDiameterInvasive</b></p><a name="BreastResectionMaxDiameterInvasive"> </a><a name="hcBreastResectionMaxDiameterInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44635-1}, {http://snomed.info/sct 200001000004104}">Maximaler Durchmesser invasives Karzinom</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 18 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44635-1"/>
            <display value="Inv comp size max dim BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="200001000004104"/>
            <display value="Greatest length dimension of excised primary malignant neoplasm (observable entity)"/>
          </coding>
          <text value="Maximaler Durchmesser invasives Karzinom"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="18"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMaxOverallDiameter"/>
    <resource>
      <Observation>
        <id value="BreastResectionMaxOverallDiameter"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMaxOverallDiameter"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMaxOverallDiameter</b></p><a name="BreastResectionMaxOverallDiameter"> </a><a name="hcBreastResectionMaxOverallDiameter"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 33728-7}">Maximaler Gesamtdurchmesser der Läsion</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 22 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="33728-7"/>
            <display value="Size.maximum dimension in Tumor"/>
          </coding>
          <text value="Maximaler Gesamtdurchmesser der Läsion"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="22"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionHistologicalType"/>
    <resource>
      <Observation>
        <id value="BreastResectionHistologicalType"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionHistologicalType"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionHistologicalType</b></p><a name="BreastResectionHistologicalType"> </a><a name="hcBreastResectionHistologicalType"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44638-5}, {http://snomed.info/sct 1660001000004100}">Histologischer Tumortyp WHO</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 82711006}">Invasives duktales Karzinom (NST)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44638-5"/>
            <display value="Histo type BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1660001000004100"/>
            <display value="Histologic type of primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Histologischer Tumortyp WHO"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="82711006"/>
            <display value="Infiltrating duct carcinoma (morphologic abnormality)"/>
          </coding>
          <text value="Invasives duktales Karzinom (NST)"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMorphologyFreeText"/>
    <resource>
      <Observation>
        <id value="BreastResectionMorphologyFreeText"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMorphologyFreeText"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMorphologyFreeText</b></p><a name="BreastResectionMorphologyFreeText"> </a><a name="hcBreastResectionMorphologyFreeText"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 33731-1}">Morphologie Freitext</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.</p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="33731-1"/>
            <display value="Histology type in Cancer specimen Narrative"/>
          </coding>
          <text value="Morphologie Freitext"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString value="Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion."/>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionNottinghamGrade"/>
    <resource>
      <Observation>
        <id value="BreastResectionNottinghamGrade"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionNottinghamGrade"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionNottinghamGrade</b></p><a name="BreastResectionNottinghamGrade"> </a><a name="hcBreastResectionNottinghamGrade"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 372276001}">Histologischer Tumorgrad (Nottingham-Grad)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 1155703007}">Nottingham Grad 2</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: </p><ul><li><a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href="Observation-BreastResectionNottinghamSummaryScore.html">Observation Nottingham total score of primary malignant neoplasm of breast (observable entity)</a></li></ul></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="372276001"/>
            <display value="Nottingham combined grade of primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Histologischer Tumorgrad (Nottingham-Grad)"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1155703007"/>
            <display value="G2: Moderately differentiated histologic grade (qualifier value)"/>
          </coding>
          <text value="Nottingham Grad 2"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <derivedFrom>
          <reference value="Observation/BreastResectionNottinghamSummaryScore"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionNottinghamSummaryScore"/>
    <resource>
      <Observation>
        <id value="BreastResectionNottinghamSummaryScore"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionNottinghamSummaryScore"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionNottinghamSummaryScore</b></p><a name="BreastResectionNottinghamSummaryScore"> </a><a name="hcBreastResectionNottinghamSummaryScore"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1287461000}">Elston-Ellis-Summenscore</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 6 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85321-8}">Glandular differentiation [Score] in Breast cancer specimen by Nottingham</span></p><p><b>value</b>: 3 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44645-0}">Nuclear pleomorphism in Breast tumor by Nottingham</span></p><p><b>value</b>: 2 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85300-2}">Mitotic rate [Score] in Breast cancer specimen by Nottingham</span></p><p><b>value</b>: 1 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p></blockquote></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1287461000"/>
            <display value="Nottingham total score of primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Elston-Ellis-Summenscore"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="6"/>
          <unit value="score"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{score}"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="85321-8"/>
              <display value="Glandular differentiation [Score] in Breast cancer specimen by Nottingham"/>
            </coding>
          </code>
          <valueQuantity>
            <value value="3"/>
            <unit value="score"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="{score}"/>
          </valueQuantity>
        </component>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="44645-0"/>
              <display value="Nuclear pleomorphism in Breast tumor by Nottingham"/>
            </coding>
          </code>
          <valueQuantity>
            <value value="2"/>
            <unit value="score"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="{score}"/>
          </valueQuantity>
        </component>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="85300-2"/>
              <display value="Mitotic rate [Score] in Breast cancer specimen by Nottingham"/>
            </coding>
          </code>
          <valueQuantity>
            <value value="1"/>
            <unit value="score"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="{score}"/>
          </valueQuantity>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMitosisCount"/>
    <resource>
      <Observation>
        <id value="BreastResectionMitosisCount"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMitosisCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMitosisCount</b></p><a name="BreastResectionMitosisCount"> </a><a name="hcBreastResectionMitosisCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 406094009}">Mitosezahl</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 4 per 10 HPF<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{HPF} = '{HPF}')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="406094009"/>
            <display value="Number of mitoses per 10 high power fields (observable entity)"/>
          </coding>
          <text value="Mitosezahl"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="4"/>
          <unit value="per 10 HPF"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{HPF}"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionAssociatedDCIS"/>
    <resource>
      <Observation>
        <id value="BreastResectionAssociatedDCIS"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionAssociatedDCIS"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionAssociatedDCIS</b></p><a name="BreastResectionAssociatedDCIS"> </a><a name="hcBreastResectionAssociatedDCIS"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85336-6}">Klassifikation eines assoziiertes DCIS</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA27260-1}">DCIS vorhanden, ohne extensive intraduktale Komponente (EIC)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85336-6"/>
            <display value="DCIS intraduct ext Br ca spec Ql Micro"/>
          </coding>
          <text value="Klassifikation eines assoziiertes DCIS"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA27260-1"/>
            <display value="DCIS present without extensive intraductal component (EIC)"/>
          </coding>
          <text value="DCIS vorhanden, ohne extensive intraduktale Komponente (EIC)"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionDCISGrade"/>
    <resource>
      <Observation>
        <id value="BreastResectionDCISGrade"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionDCISGrade"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionDCISGrade</b></p><a name="BreastResectionDCISGrade"> </a><a name="hcBreastResectionDCISGrade"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 2890001000004108}">Kerngrading / WHO-Grading nichtinvasiv</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 369782002}">Intermediär (Grad 2)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2890001000004108"/>
            <display value="Nuclear grade of ductal carcinoma in situ of breast (observable entity)"/>
          </coding>
          <text value="Kerngrading / WHO-Grading nichtinvasiv"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="369782002"/>
            <display value="Ductal carcinoma in situ nuclear pleomorphism, grade 2: neither nuclear grade 1 nor nuclear grade 3 (finding)"/>
          </coding>
          <text value="Intermediär (Grad 2)"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionDCISArchitecture"/>
    <resource>
      <Observation>
        <id value="BreastResectionDCISArchitecture"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionDCISArchitecture"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionDCISArchitecture</b></p><a name="BreastResectionDCISArchitecture"> </a><a name="hcBreastResectionDCISArchitecture"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85302-8}, {http://snomed.info/sct 3400001000004108}">DCIS Architektur</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 443987001}">kribriformer Typ</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85302-8"/>
            <display value="Growth pattern of DCIS [Type] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3400001000004108"/>
            <display value="Architectural pattern of ductal carcinoma in situ in breast (observable entity)"/>
          </coding>
          <text value="DCIS Architektur"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="443987001"/>
            <display value="Cribriform neoplasm pattern (finding)"/>
          </coding>
          <text value="kribriformer Typ"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionDCISNecrosis"/>
    <resource>
      <Observation>
        <id value="BreastResectionDCISNecrosis"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionDCISNecrosis"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionDCISNecrosis</b></p><a name="BreastResectionDCISNecrosis"> </a><a name="hcBreastResectionDCISNecrosis"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85340-8}">Nekrosen</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA27235-3}">Zentral (Komedo-Nekrosen)</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85340-8"/>
            <display value="DCIS necrosis [Type] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <text value="Nekrosen"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA27235-3"/>
            <display value="Present, central (expansive &quot;comedo&quot; necrosis)"/>
          </coding>
          <text value="Zentral (Komedo-Nekrosen)"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionTumorExtent"/>
    <resource>
      <Observation>
        <id value="BreastResectionTumorExtent"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionTumorExtent"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionTumorExtent</b></p><a name="BreastResectionTumorExtent"> </a><a name="hcBreastResectionTumorExtent"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85322-6}, {http://snomed.info/sct 396645007}, {http://snomed.info/sct 3280001000004106}">Tumorausdehnung</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 372288004}">Auf Brustdrüse beschränkt</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85322-6"/>
            <display value="Adjacent structure invaded by tumor [Anatomy] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="396645007"/>
            <display value="Status of extension by tumor (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3280001000004106"/>
            <display value="Anatomic location directly invaded by primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Tumorausdehnung"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="372288004"/>
            <display value="Local tumor invasion (finding)"/>
          </coding>
          <text value="Auf Brustdrüse beschränkt"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMarginStatusInvasive"/>
    <resource>
      <Observation>
        <id value="BreastResectionMarginStatusInvasive"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMarginStatusInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMarginStatusInvasive</b></p><a name="BreastResectionMarginStatusInvasive"> </a><a name="hcBreastResectionMarginStatusInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44669-0}, {http://snomed.info/sct 371488000}, {http://snomed.info/sct 1240395000}">Resektionsrandstatus invasiv</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht befallen (R0)</span></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44669-0"/>
            <display value="Margin involved BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371488000"/>
            <display value="Presence of neoplasm at excised surgical margin (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1240395000"/>
            <display value="Surgical margin involved by primary malignant neoplasm of breast in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Resektionsrandstatus invasiv"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht befallen (R0)"/>
        </valueCodeableConcept>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionClosestMargin"/>
    <resource>
      <Observation>
        <id value="BreastResectionClosestMargin"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionClosestMargin"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionClosestMargin</b></p><a name="BreastResectionClosestMargin"> </a><a name="hcBreastResectionClosestMargin"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44674-0}, {http://snomed.info/sct 170001000004107}">Richtung des nächsten tumorfreien RR</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 255551008}">Posterior</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideRR-Posterior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_7_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44674-0"/>
            <display value="IC uninv marg closest BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="170001000004107"/>
            <display value="Surgical margin closest to malignant neoplasm in excised specimen of breast (observable entity)"/>
          </coding>
          <text value="Richtung des nächsten tumorfreien RR"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="255551008"/>
            <display value="Posterior (qualifier value)"/>
          </coding>
          <text value="Posterior"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideRR-Posterior-HE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMinDistanceInvasive"/>
    <resource>
      <Observation>
        <id value="BreastResectionMinDistanceInvasive"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMinDistanceInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMinDistanceInvasive</b></p><a name="BreastResectionMinDistanceInvasive"> </a><a name="hcBreastResectionMinDistanceInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44672-4}, {http://snomed.info/sct 373120008}">Mindestabstand des invasiven Tumor zum nächstgelegenen Resektionsrand</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 5 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideRR-Posterior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_7_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44672-4"/>
            <display value="IC uninv marg dist closest BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="373120008"/>
            <display value="Distance of invasive carcinoma of breast from closest surgical margin in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Mindestabstand des invasiven Tumor zum nächstgelegenen Resektionsrand"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="5"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideRR-Posterior-HE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMarginStatusNonInvasive"/>
    <resource>
      <Observation>
        <id value="BreastResectionMarginStatusNonInvasive"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMarginStatusNonInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMarginStatusNonInvasive</b></p><a name="BreastResectionMarginStatusNonInvasive"> </a><a name="hcBreastResectionMarginStatusNonInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85334-1}, {http://snomed.info/sct 384705006}">Resektionsrandstatus nichtinvasiv</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht befallen</span></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85334-1"/>
            <display value="Surgical margin DCIS involvement [Presence] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="384705006"/>
            <display value="Presence of ductal carcinoma in situ at surgical margin in excised specimen of breast (observable entity)"/>
          </coding>
          <text value="Resektionsrandstatus nichtinvasiv"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht befallen"/>
        </valueCodeableConcept>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMinDistanceNonInvasive"/>
    <resource>
      <Observation>
        <id value="BreastResectionMinDistanceNonInvasive"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMinDistanceNonInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMinDistanceNonInvasive</b></p><a name="BreastResectionMinDistanceNonInvasive"> </a><a name="hcBreastResectionMinDistanceNonInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44673-2}">Mindestabstand vom RR zum nichtinvasiven Tumor</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 3 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44673-2"/>
            <display value="DCIS.uninv marg dist.closest BT"/>
          </coding>
          <text value="Mindestabstand vom RR zum nichtinvasiven Tumor"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="3"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionLVI"/>
    <resource>
      <Observation>
        <id value="BreastResectionLVI"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionLVI"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionLVI</b></p><a name="BreastResectionLVI"> </a><a name="hcBreastResectionLVI"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 59544-7}, {http://snomed.info/sct 371512006}">Peritumorale Gefäßinvasion</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht nachgewiesen</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. Mit Haut, Drahthäkchen in situ.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="59544-7"/>
            <display value="Lymph-vascular invasion Ca spec"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371512006"/>
            <display value="Presence of direct invasion by primary malignant neoplasm to lymphatic vessel and/or small blood vessel (observable entity)"/>
          </coding>
          <text value="Peritumorale Gefäßinvasion"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht nachgewiesen"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenPart"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionMicrocalcification"/>
    <resource>
      <Observation>
        <id value="BreastResectionMicrocalcification"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionMicrocalcification"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionMicrocalcification</b></p><a name="BreastResectionMicrocalcification"> </a><a name="hcBreastResectionMicrocalcification"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1240404008}">Presence of microcalcification in excised breast specimen (observable entity)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA27826-9}">Microcalcifications present in DCIS</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1240404008"/>
            <display value="Presence of microcalcification in excised breast specimen (observable entity)"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA27826-9"/>
            <display value="Microcalcifications present in DCIS"/>
          </coding>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHE01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionERStatus"/>
    <resource>
      <Observation>
        <id value="BreastResectionERStatus"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionERStatus"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionERStatus</b></p><a name="BreastResectionERStatus"> </a><a name="hcBreastResectionERStatus"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 16112-5}, {http://snomed.info/sct 1234806008}">Hormonrezeptorstatus Östrogen</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA6576-8}">Positiv</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideER01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3467}">ESR1</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="16112-5"/>
            <display value="Estrogen receptor [Interpretation] in Tissue"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Hormonrezeptorstatus Östrogen"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA6576-8"/>
            <display value="Positive"/>
          </coding>
          <text value="Positiv"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideER01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3467"/>
              <display value="ESR1"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionERPercentage"/>
    <resource>
      <Observation>
        <id value="BreastResectionERPercentage"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionERPercentage"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionERPercentage</b></p><a name="BreastResectionERPercentage"> </a><a name="hcBreastResectionERPercentage"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85329-1}, {http://snomed.info/sct 1234804006}, {http://snomed.info/sct 1234806008}">PP ER</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 90 %<span style="background: LightGoldenRodYellow"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideER01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3467}">ESR1</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85329-1"/>
            <display value="Cells.estrogen receptor/cells in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234804006"/>
            <display value="Percent of cells with estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="PP ER"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="90"/>
          <unit value="%"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="%"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideER01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3467"/>
              <display value="ESR1"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionERIntensity"/>
    <resource>
      <Observation>
        <id value="BreastResectionERIntensity"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionERIntensity"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionERIntensity</b></p><a name="BreastResectionERIntensity"> </a><a name="hcBreastResectionERIntensity"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85310-1}, {http://snomed.info/sct 1236874005}, {http://snomed.info/sct 1234806008}">Färbeintensität ER</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 24484000}">Stark</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideER01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3467}">ESR1</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85310-1"/>
            <display value="Estrogen receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1236874005"/>
            <display value="Intensity of stain of estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Färbeintensität ER"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="24484000"/>
            <display value="Severe (severity modifier) (qualifier value)"/>
          </coding>
          <text value="Stark"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideER01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3467"/>
              <display value="ESR1"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionPRStatus"/>
    <resource>
      <Observation>
        <id value="BreastResectionPRStatus"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionPRStatus"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionPRStatus</b></p><a name="BreastResectionPRStatus"> </a><a name="hcBreastResectionPRStatus"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 16113-3}, {http://snomed.info/sct 1234806008}">Hormonrezeptorstatus Progesteron</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA6576-8}">Positiv</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlidePR01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:8910}">PGR</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="16113-3"/>
            <display value="Progesterone receptor [Interpretation] in Tissue"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Hormonrezeptorstatus Progesteron"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA6576-8"/>
            <display value="Positive"/>
          </coding>
          <text value="Positiv"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlidePR01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:8910"/>
              <display value="PGR"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionPRPercentage"/>
    <resource>
      <Observation>
        <id value="BreastResectionPRPercentage"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionPRPercentage"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionPRPercentage</b></p><a name="BreastResectionPRPercentage"> </a><a name="hcBreastResectionPRPercentage"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85325-9}, {http://snomed.info/sct 1234803000}, {http://snomed.info/sct 1234806008}">PP PR</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 60 %<span style="background: LightGoldenRodYellow"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlidePR01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:8910}">PGR</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85325-9"/>
            <display value="Cells.progesterone receptor/cells in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234803000"/>
            <display value="Percent of cells with progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="PP PR"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="60"/>
          <unit value="%"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="%"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlidePR01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:8910"/>
              <display value="PGR"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionPRIntensity"/>
    <resource>
      <Observation>
        <id value="BreastResectionPRIntensity"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionPRIntensity"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionPRIntensity</b></p><a name="BreastResectionPRIntensity"> </a><a name="hcBreastResectionPRIntensity"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1237278006}">Färbeintensität PR</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 6736007}">Mäßig</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlidePR01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:8910}">PGR</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1237278006"/>
            <display value="Intensity of stain of progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Färbeintensität PR"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="6736007"/>
            <display value="Moderate (severity modifier) (qualifier value)"/>
          </coding>
          <text value="Mäßig"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlidePR01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:8910"/>
              <display value="PGR"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionHER2IHC"/>
    <resource>
      <Observation>
        <id value="BreastResectionHER2IHC"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionHER2IHC"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionHER2IHC</b></p><a name="BreastResectionHER2IHC"> </a><a name="hcBreastResectionHER2IHC"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85319-2}, {http://snomed.info/sct 3550001000004108}, {http://snomed.info/sct 1234806008}">Her2 Score</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA11841-6}">1+</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHER2IHC01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HER2IHC_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3430}">ERBB2</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85319-2"/>
            <display value="HER2 [Presence] in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3550001000004108"/>
            <display value="Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Her2 Score"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA11841-6"/>
            <display value="1+"/>
          </coding>
          <text value="1+"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHER2IHC01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3430"/>
              <display value="ERBB2"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionHER2ISH"/>
    <resource>
      <Observation>
        <id value="BreastResectionHER2ISH"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionHER2ISH"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionHER2ISH</b></p><a name="BreastResectionHER2ISH"> </a><a name="hcBreastResectionHER2ISH"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1363314005}">Her2 Amplifikation</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 705105000}">Nicht amplifiziert</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHER2IHC01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HER2IHC_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3430}">ERBB2</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1363314005"/>
            <display value="Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by in situ hybridization (observable entity)"/>
          </coding>
          <text value="Her2 Amplifikation"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="705105000"/>
            <display value="Human epidermal growth factor 2 gene amplification not detected (finding)"/>
          </coding>
          <text value="Nicht amplifiziert"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHER2IHC01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3430"/>
              <display value="ERBB2"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionHER2Overall"/>
    <resource>
      <Observation>
        <id value="BreastResectionHER2Overall"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionHER2Overall"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionHER2Overall</b></p><a name="BreastResectionHER2Overall"> </a><a name="hcBreastResectionHER2Overall"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 48676-1}">Her2neuStatus</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA6577-6}">Negativ</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideHER2IHC01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_HER2IHC_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3430}">ERBB2</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="48676-1"/>
            <display value="HER2 [Interpretation] in Tissue"/>
          </coding>
          <text value="Her2neuStatus"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA6577-6"/>
            <display value="Negative"/>
          </coding>
          <text value="Negativ"/>
        </valueCodeableConcept>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideHER2IHC01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3430"/>
              <display value="ERBB2"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionKi67"/>
    <resource>
      <Observation>
        <id value="BreastResectionKi67"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionKi67"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionKi67</b></p><a name="BreastResectionKi67"> </a><a name="hcBreastResectionKi67"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85330-9}, {http://snomed.info/sct 1237281001}, {http://snomed.info/sct 1234806008}">Ki67-Index</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 15 %<span style="background: LightGoldenRodYellow"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href="Specimen-BreastResectionSpecimenSlideKi67-01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210_A_1_1_Ki67_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_210; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:7107}">MKI67</span></td></tr></table></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85330-9"/>
            <display value="Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1237281001"/>
            <display value="Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Ki67-Index"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="15"/>
          <unit value="%"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="%"/>
        </valueQuantity>
        <specimen>
          <reference value="Specimen/BreastResectionSpecimenSlideKi67-01"/>
        </specimen>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:7107"/>
              <display value="MKI67"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionPT"/>
    <resource>
      <Observation>
        <id value="BreastResectionPT"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionPT"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionPT</b></p><a name="BreastResectionPT"> </a><a name="hcBreastResectionPT"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie">MII PR Onkologie TNM T-Kategorie</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 384625004}">pT category (observable entity)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>value</b>: <span title="Codes:{https://www.uicc.org/resources/tnm T1}">T1</span></p><p><b>method</b>: <span title="Codes:{https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version 8}">8. Auflage</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <extension url="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix">
            <valueCodeableConcept>
              <coding>
                <system value="https://www.uicc.org/resources/tnm"/>
                <code value="p"/>
                <display value="p"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="384625004"/>
            <display value="pT category (observable entity)"/>
          </coding>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <valueCodeableConcept>
          <coding>
            <system value="https://www.uicc.org/resources/tnm"/>
            <code value="T1"/>
            <display value="T1"/>
          </coding>
        </valueCodeableConcept>
        <method>
          <coding>
            <system value="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version"/>
            <code value="8"/>
            <display value="8. Auflage"/>
          </coding>
        </method>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/BreastResectionComment"/>
    <resource>
      <Observation>
        <id value="BreastResectionComment"/>
        <meta>
          <profile value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_BreastResectionComment"> </a><p class="res-header-id"><b>Generated Narrative: Observation BreastResectionComment</b></p><a name="BreastResectionComment"> </a><a name="hcBreastResectionComment"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-BreastResectionReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22638-1}">Kommentar</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-QuestionnaireResponseBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>
          <reference value="ServiceRequest/BreastResectionReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22638-1"/>
            <display value="Pathology report comments [Interpretation] Narrative"/>
          </coding>
          <text value="Kommentar"/>
        </code>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString value="Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung."/>
        <derivedFrom>
          <reference value="QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/QuestionnaireResponse/QuestionnaireResponseBreastResection"/>
    <resource>
      <QuestionnaireResponse>
        <id value="QuestionnaireResponseBreastResection"/>
        <text>
          <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><a name="QuestionnaireResponse_QuestionnaireResponseBreastResection"> </a><p class="res-header-id"><b>Generated Narrative: QuestionnaireResponse QuestionnaireResponseBreastResection</b></p><a name="QuestionnaireResponseBreastResection"> </a><a name="hcQuestionnaireResponseBreastResection"> </a><table border="1" cellpadding="0" cellspacing="0" style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 2px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="The linkID for the item">LinkID</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Text for the item">Text</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Minimum and Maximum # of times the item can appear in the instance">Definition</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="The type of the item">Answer</a><span style="float: right"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_q_root.gif" alt="." style="background-color: white; background-color: inherit" title="QuestionnaireResponseRoot" class="hierarchy"/> QuestionnaireResponseBreastResection</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Questionnaire:http://breastcancerspec.org/Questionnaire/OP-Mamma</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.root</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">BET Mamma</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> bet.clinical</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Klinische Angaben</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11951</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Proben limitiert auswertbar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/373067005">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11912</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Präsentationsmodus</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Frisch</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11147</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Klinische Befunde / Anlass</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Z.n. Stanzbiopsie mit Nachweis eines invasiven Mammakarzinoms NST, G2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11923</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Brustkrebsvorgeschichte</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ersterkrankung</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11952</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Vorchirurgische Therapie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/373067005">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11918</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Bildgebungsmodalität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mammografie, Ultraschall</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11953</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Radiologische Ausdehnung</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>15 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10160</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Befundmarkierung</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Drahthäkchen</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10130</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Präparateradiographie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ja, beigelegt</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11954</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Genetische Prädisposition</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nicht bekannt</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.macro</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Makroskopie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10900</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Probengröße 1 (Länge)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>65 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10910</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Probengröße 2 (Breite)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>45 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10920</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Probengröße 3 (Tiefe)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>30 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10890</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gewicht</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>55 g<span style="background: LightGoldenRodYellow"> (Details: UCUM  codeg = 'g')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10030</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Quadrant</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/33564002">SNOMED CT: 33564002</a> (Structure of lower outer quadrant of breast (body structure))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10040</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Zifferblattlokalisation</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">5 Uhr</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10070</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Abstand Mamille</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>50 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.general</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Allgemeine Befunde</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11130</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nichtinvasive Läsion</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11270</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Karzinom</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11919</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Operatives Verfahren</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/237371007">SNOMED CT: 237371007</a> (Wide local excision of breast lesion (procedure))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10140</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Materialart</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Exzisionspräparat</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10800</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Seitenlokalisation</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/7771000">SNOMED CT: 7771000</a> (Left (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11040</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Anhängendes Gewebe</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Haut</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11440</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Fokalität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Unifokal</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.invasive</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Karzinom</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11400</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Max Durchmesser invasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>18 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11420</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Max Gesamtdurchmesser</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>22 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11280</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Histologischer Tumortyp</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>unknown: 8500/3 (Invasives duktales Karzinom (NST))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11290</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Morphologie Freitext</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Mammakarzinom des NST, überwiegend trabekuläres und solides Wachstumsmuster</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11330</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nottingham-Grad</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">G2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11340</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Tubulus-Score</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">3</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11350</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kernpleomorphie-Score</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11925</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mitosezahl</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">4/10 HPF</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11360</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mitoserate-Score</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11390</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Elston-Ellis-Summenscore</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">6</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11300</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Assoziiertes DCIS</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 149</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">DCIS Kerngrading</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Intermediär (Grad 2)</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 150</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">DCIS Architektur</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kribriform</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 151</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">DCIS Nekrosen</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Fokal (Komedo-Nekrosen)</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11926</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Tumorausdehnung</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Auf Brustdrüse beschränkt</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.margins</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Resektionsränder</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11470</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">RR-Status invasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11490</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nächster tumorfreier RR</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Posterior</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11480</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mindestabstand invasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>5 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11968</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">RR-Status nichtinvasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11970</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mindestabstand nichtinvasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>3 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.additional</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Weitere Befunde</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11430</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">LVI</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10880</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mikrokalzifikationen</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">In DCIS assoziiert</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> bet.biomarkers</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Biomarker</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11750</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ER-Status</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11720</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ER Prozent</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">90</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11730</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ER Färbeintensität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Stark</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11790</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">PR-Status</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11760</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">PR Prozent</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">60</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11770</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">PR Färbeintensität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mäßig</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11810</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HER2-Score (IHC)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1+</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11820</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HER2-Amplifikation (ISH)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nicht amplifiziert</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11830</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HER2-Gesamtstatus</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Negativ</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11840</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ki-67-Index</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">15</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.tnm</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">TNM</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 169</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">pT-Kategorie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">pT1c</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck001.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.comment</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kommentar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0000.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11900</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kommentar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</td></tr>
<tr><td colspan="4" class="hierarchy"><br/><a href="https://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
        </text>
        <questionnaire value="http://breastcancerspec.org/Questionnaire/OP-Mamma"/>
        <status value="completed"/>
        <subject>
          <reference value="Patient/Patient4"/>
        </subject>
        <authored value="2025-02-10T14:30:00+01:00"/>
        <author>
          <reference value="Practitioner/PathologistPractitioner"/>
        </author>
        <item>
          <linkId value="bet.root"/>
          <text value="BET Mamma"/>
          <item>
            <linkId value="bet.clinical"/>
            <text value="Klinische Angaben"/>
            <item>
              <linkId value="11951"/>
              <text value="Proben limitiert auswertbar"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="373067005"/>
                  <display value="No (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11912"/>
              <text value="Präsentationsmodus"/>
              <answer>
                <valueString value="Frisch"/>
              </answer>
            </item>
            <item>
              <linkId value="11147"/>
              <text value="Klinische Befunde / Anlass"/>
              <answer>
                <valueString value="Z.n. Stanzbiopsie mit Nachweis eines invasiven Mammakarzinoms NST, G2"/>
              </answer>
            </item>
            <item>
              <linkId value="11923"/>
              <text value="Brustkrebsvorgeschichte"/>
              <answer>
                <valueString value="Ersterkrankung"/>
              </answer>
            </item>
            <item>
              <linkId value="11952"/>
              <text value="Vorchirurgische Therapie"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="373067005"/>
                  <display value="No (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11918"/>
              <text value="Bildgebungsmodalität"/>
              <answer>
                <valueString value="Mammografie, Ultraschall"/>
              </answer>
            </item>
            <item>
              <linkId value="11953"/>
              <text value="Radiologische Ausdehnung"/>
              <answer>
                <valueQuantity>
                  <value value="15"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10160"/>
              <text value="Befundmarkierung"/>
              <answer>
                <valueString value="Drahthäkchen"/>
              </answer>
            </item>
            <item>
              <linkId value="10130"/>
              <text value="Präparateradiographie"/>
              <answer>
                <valueString value="Ja, beigelegt"/>
              </answer>
            </item>
            <item>
              <linkId value="11954"/>
              <text value="Genetische Prädisposition"/>
              <answer>
                <valueString value="Nicht bekannt"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.macro"/>
            <text value="Makroskopie"/>
            <item>
              <linkId value="10900"/>
              <text value="Probengröße 1 (Länge)"/>
              <answer>
                <valueQuantity>
                  <value value="65"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10910"/>
              <text value="Probengröße 2 (Breite)"/>
              <answer>
                <valueQuantity>
                  <value value="45"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10920"/>
              <text value="Probengröße 3 (Tiefe)"/>
              <answer>
                <valueQuantity>
                  <value value="30"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10890"/>
              <text value="Gewicht"/>
              <answer>
                <valueQuantity>
                  <value value="55"/>
                  <unit value="g"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="g"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10030"/>
              <text value="Quadrant"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="33564002"/>
                  <display value="Structure of lower outer quadrant of breast (body structure)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="10040"/>
              <text value="Zifferblattlokalisation"/>
              <answer>
                <valueString value="5 Uhr"/>
              </answer>
            </item>
            <item>
              <linkId value="10070"/>
              <text value="Abstand Mamille"/>
              <answer>
                <valueQuantity>
                  <value value="50"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.general"/>
            <text value="Allgemeine Befunde"/>
            <item>
              <linkId value="11130"/>
              <text value="Nichtinvasive Läsion"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11270"/>
              <text value="Invasives Karzinom"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11919"/>
              <text value="Operatives Verfahren"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="237371007"/>
                  <display value="Wide local excision of breast lesion (procedure)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="10140"/>
              <text value="Materialart"/>
              <answer>
                <valueString value="Exzisionspräparat"/>
              </answer>
            </item>
            <item>
              <linkId value="10800"/>
              <text value="Seitenlokalisation"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="7771000"/>
                  <display value="Left (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11040"/>
              <text value="Anhängendes Gewebe"/>
              <answer>
                <valueString value="Haut"/>
              </answer>
            </item>
            <item>
              <linkId value="11440"/>
              <text value="Fokalität"/>
              <answer>
                <valueString value="Unifokal"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.invasive"/>
            <text value="Invasives Karzinom"/>
            <item>
              <linkId value="11400"/>
              <text value="Max Durchmesser invasiv"/>
              <answer>
                <valueQuantity>
                  <value value="18"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11420"/>
              <text value="Max Gesamtdurchmesser"/>
              <answer>
                <valueQuantity>
                  <value value="22"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11280"/>
              <text value="Histologischer Tumortyp"/>
              <answer>
                <valueCoding>
                  <system value="urn:oid:2.16.840.1.113883.6.43.1"/>
                  <code value="8500/3"/>
                  <display value="Invasives duktales Karzinom (NST)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11290"/>
              <text value="Morphologie Freitext"/>
              <answer>
                <valueString value="Invasives Mammakarzinom des NST, überwiegend trabekuläres und solides Wachstumsmuster"/>
              </answer>
            </item>
            <item>
              <linkId value="11330"/>
              <text value="Nottingham-Grad"/>
              <answer>
                <valueString value="G2"/>
              </answer>
            </item>
            <item>
              <linkId value="11340"/>
              <text value="Tubulus-Score"/>
              <answer>
                <valueInteger value="3"/>
              </answer>
            </item>
            <item>
              <linkId value="11350"/>
              <text value="Kernpleomorphie-Score"/>
              <answer>
                <valueInteger value="2"/>
              </answer>
            </item>
            <item>
              <linkId value="11925"/>
              <text value="Mitosezahl"/>
              <answer>
                <valueString value="4/10 HPF"/>
              </answer>
            </item>
            <item>
              <linkId value="11360"/>
              <text value="Mitoserate-Score"/>
              <answer>
                <valueInteger value="1"/>
              </answer>
            </item>
            <item>
              <linkId value="11390"/>
              <text value="Elston-Ellis-Summenscore"/>
              <answer>
                <valueInteger value="6"/>
              </answer>
            </item>
            <item>
              <linkId value="11300"/>
              <text value="Assoziiertes DCIS"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="149"/>
              <text value="DCIS Kerngrading"/>
              <answer>
                <valueString value="Intermediär (Grad 2)"/>
              </answer>
            </item>
            <item>
              <linkId value="150"/>
              <text value="DCIS Architektur"/>
              <answer>
                <valueString value="Kribriform"/>
              </answer>
            </item>
            <item>
              <linkId value="151"/>
              <text value="DCIS Nekrosen"/>
              <answer>
                <valueString value="Fokal (Komedo-Nekrosen)"/>
              </answer>
            </item>
            <item>
              <linkId value="11926"/>
              <text value="Tumorausdehnung"/>
              <answer>
                <valueString value="Auf Brustdrüse beschränkt"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.margins"/>
            <text value="Resektionsränder"/>
            <item>
              <linkId value="11470"/>
              <text value="RR-Status invasiv"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11490"/>
              <text value="Nächster tumorfreier RR"/>
              <answer>
                <valueString value="Posterior"/>
              </answer>
            </item>
            <item>
              <linkId value="11480"/>
              <text value="Mindestabstand invasiv"/>
              <answer>
                <valueQuantity>
                  <value value="5"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11968"/>
              <text value="RR-Status nichtinvasiv"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11970"/>
              <text value="Mindestabstand nichtinvasiv"/>
              <answer>
                <valueQuantity>
                  <value value="3"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.additional"/>
            <text value="Weitere Befunde"/>
            <item>
              <linkId value="11430"/>
              <text value="LVI"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="10880"/>
              <text value="Mikrokalzifikationen"/>
              <answer>
                <valueString value="In DCIS assoziiert"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.biomarkers"/>
            <text value="Biomarker"/>
            <item>
              <linkId value="11750"/>
              <text value="ER-Status"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11720"/>
              <text value="ER Prozent"/>
              <answer>
                <valueInteger value="90"/>
              </answer>
            </item>
            <item>
              <linkId value="11730"/>
              <text value="ER Färbeintensität"/>
              <answer>
                <valueString value="Stark"/>
              </answer>
            </item>
            <item>
              <linkId value="11790"/>
              <text value="PR-Status"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11760"/>
              <text value="PR Prozent"/>
              <answer>
                <valueInteger value="60"/>
              </answer>
            </item>
            <item>
              <linkId value="11770"/>
              <text value="PR Färbeintensität"/>
              <answer>
                <valueString value="Mäßig"/>
              </answer>
            </item>
            <item>
              <linkId value="11810"/>
              <text value="HER2-Score (IHC)"/>
              <answer>
                <valueString value="1+"/>
              </answer>
            </item>
            <item>
              <linkId value="11820"/>
              <text value="HER2-Amplifikation (ISH)"/>
              <answer>
                <valueString value="Nicht amplifiziert"/>
              </answer>
            </item>
            <item>
              <linkId value="11830"/>
              <text value="HER2-Gesamtstatus"/>
              <answer>
                <valueString value="Negativ"/>
              </answer>
            </item>
            <item>
              <linkId value="11840"/>
              <text value="Ki-67-Index"/>
              <answer>
                <valueInteger value="15"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.tnm"/>
            <text value="TNM"/>
            <item>
              <linkId value="169"/>
              <text value="pT-Kategorie"/>
              <answer>
                <valueString value="pT1c"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.comment"/>
            <text value="Kommentar"/>
            <item>
              <linkId value="11900"/>
              <text value="Kommentar"/>
              <answer>
                <valueString value="Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung."/>
              </answer>
            </item>
          </item>
        </item>
      </QuestionnaireResponse>
    </resource>
  </entry>
</Bundle>