{
  "resourceType" : "Bundle",
  "id" : "IntegratedDocument",
  "identifier" : {
    "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
    "value" : "E_25_004"
  },
  "type" : "document",
  "timestamp" : "2025-02-10T17:00:00+01:00",
  "entry" : [{
    "fullUrl" : "http://breastcancerspec.org/Composition/IntegratedComposition",
    "resource" : {
      "resourceType" : "Composition",
      "id" : "IntegratedComposition",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Composition_IntegratedComposition\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Composition IntegratedComposition</b></p><a name=\"IntegratedComposition\"> </a><a name=\"hcIntegratedComposition\"> </a><p><b>identifier</b>: Accession ID/PATH-COMP-2025-300</p><p><b>status</b>: Final</p><p><b>type</b>: <span title=\"Codes:{http://ihe-d.de/CodeSystems/IHEXDStypeCode PATH}, {http://snomed.info/sct 371528001}\">Pathology report (record artifact)</span></p><p><b>encounter</b>: <a href=\"Encounter-IntegratedEncounter.html\">Encounter: identifier = http://example.hospital.de/encounters#E_25_300; status = finished; class = IMP (IMP)</a></p><p><b>date</b>: 2025-02-10 17:00:00+0100</p><p><b>author</b>: <a href=\"Organization-PathologyLabOrganization.html\">Institut für Pathologie</a></p><p><b>title</b>: Histopathologischer Befundbericht — BET Mamma links mit SLN-Biopsie Axilla</p><h3>Attesters</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Mode</b></td><td><b>Party</b></td></tr><tr><td style=\"display: none\">*</td><td>Legal</td><td><a href=\"Organization-PathologyLabOrganization.html\">Organization Institut für Pathologie</a></td></tr></table><p><b>custodian</b>: <a href=\"Organization-PathologyLabOrganization.html\">Organization Institut für Pathologie</a></p><h3>Events</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Detail</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode PATREPE}\">pathology report entry task</span></td><td><a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></td></tr></table></div>"
      },
      "identifier" : {
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }]
        },
        "system" : "http://example.hospital.de/pathology-reports",
        "value" : "PATH-COMP-2025-300"
      },
      "status" : "final",
      "type" : {
        "coding" : [{
          "system" : "http://ihe-d.de/CodeSystems/IHEXDStypeCode",
          "code" : "PATH"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "371528001",
          "display" : "Pathology report (record artifact)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4",
        "display" : "Sabine Becker, geb. 15.03.1971 (PAT-2025-105)"
      },
      "encounter" : {
        "reference" : "Encounter/IntegratedEncounter"
      },
      "date" : "2025-02-10T17:00:00+01:00",
      "author" : [{
        "reference" : "Organization/PathologyLabOrganization",
        "display" : "Institut für Pathologie"
      }],
      "title" : "Histopathologischer Befundbericht — BET Mamma links mit SLN-Biopsie Axilla",
      "attester" : [{
        "mode" : "legal",
        "party" : {
          "reference" : "Organization/PathologyLabOrganization"
        }
      }],
      "custodian" : {
        "reference" : "Organization/PathologyLabOrganization"
      },
      "event" : [{
        "code" : [{
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v3-ActCode",
            "code" : "PATREPE"
          }]
        }],
        "detail" : [{
          "reference" : "ServiceRequest/IntegratedReportRequest"
        }]
      }],
      "section" : [{
        "title" : "Pathologiebefundbericht",
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "11526-1",
            "display" : "Pathology study"
          }]
        },
        "text" : {
          "status" : "additional",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h3>Klinische Angaben</h3><p>Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links mit SLN-Biopsie Axilla indiziert. Drahthäkchenmarkierung. Keine neoadjuvante Therapie. Ersterkrankung. Keine bekannte genetische Prädisposition. Präparateradiographie beigelegt. Axilla klinisch unauffällig (cN0).</p><h3>Material</h3><p><b>A) BET-Exzisionspräparat:</b> Mamma links, mit Haut, Drahthäkchen in situ</p><p><b>B) SLN-Exzisat:</b> Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert)</p><h3>Makroskopie Mamma</h3><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>Größe</td><td>42 × 35 × 18 mm</td></tr><tr><td>Gewicht</td><td>10 g</td></tr><tr><td>Quadrant</td><td>Unterer äußerer Quadrant</td></tr><tr><td>Zifferblatt</td><td>5 Uhr</td></tr><tr><td>Abstand Mamille</td><td>50 mm</td></tr><tr><td>Lamellierung</td><td>8 Scheiben à 5 mm</td></tr><tr><td>Schnittfläche</td><td>Grau-weißlich, derber Herdbefund zentral in Scheibe III–V, ca. 18 mm</td></tr><tr><td>Paraffinblöcke</td><td>6</td></tr></tbody></table><h3>Makroskopie Axilla</h3><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>SLN #1</td><td>12 × 8 × 6 mm, Patentblau-markiert, halbiert</td></tr><tr><td>SLN #2</td><td>10 × 7 × 5 mm, Patentblau-markiert, halbiert</td></tr><tr><td>Einbettung</td><td>Beide SLN vollständig eingebettet, je 1 Paraffinblock</td></tr></tbody></table><h3>Schnellschnitt</h3><p>SLN #1: Tumorfrei im Schnellschnitt. SLN #2: Tumorfrei im Schnellschnitt. → Keine Axilladissektion.</p><p><i>Hinweis: Mikrometastase in SLN #1 erst in den Paraffinschnittstufen nachgewiesen.</i></p><h3>Mikroskopie Mamma</h3><p>Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.</p><h3>Mikroskopie Axilla</h3><p>SLN #1: Im Randsinus Nachweis einer Mikrometastase, maximal 1,2 mm messend. Keine Kapseldurchbrechung. SLN #2: In allen Schnittstufen tumorfrei. Kein Anhalt für isolierte Tumorzellen (ITC).</p><h3>Diagnostische Schlussfolgerung</h3><p><b>Diagnose:</b> Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c pN1mi(sn)</p><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>ICD-10</td><td>C50.5</td></tr><tr><td>ICD-O-3 Morphologie</td><td>M8500/3</td></tr><tr><td>Operatives Verfahren</td><td>BET (brusterhaltende Therapie) mit SLN-Biopsie</td></tr><tr><td>Seitenlokalisation</td><td>Links</td></tr><tr><td>Fokalität</td><td>Unifokal</td></tr><tr><td>Max. Durchmesser invasiv</td><td>18 mm</td></tr><tr><td>Max. Gesamtdurchmesser</td><td>22 mm</td></tr><tr><td>Nottingham-Grad</td><td>Grad 2 (Score 6: Tubuli 3, Pleomorphie 2, Mitosen 1)</td></tr><tr><td>Assoziiertes DCIS</td><td>Vorhanden, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen</td></tr><tr><td>Tumorausdehnung</td><td>Auf Brustdrüse beschränkt</td></tr></tbody></table><h4>Resektionsränder</h4><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>RR-Status invasiv</td><td>Nicht befallen (R0)</td></tr><tr><td>Nächster tumorfreier RR</td><td>Posterior</td></tr><tr><td>Mindestabstand invasiv</td><td>5 mm</td></tr><tr><td>RR-Status DCIS</td><td>Nicht befallen</td></tr><tr><td>Mindestabstand DCIS</td><td>3 mm</td></tr></tbody></table><h4>Axilläre Lymphknoten</h4><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>Prozedur</td><td>Sentinel-Lymphknoten-Biopsie</td></tr><tr><td>Untersuchte SLN</td><td>2</td></tr><tr><td>Befallene SLN</td><td>1</td></tr><tr><td>Untersuchte Non-SLN</td><td>0</td></tr><tr><td>Befallene Non-SLN</td><td>0</td></tr><tr><td>Gesamtzahl untersuchter LK</td><td>2</td></tr><tr><td>Gesamtzahl befallener LK</td><td>1</td></tr><tr><td>Makrometastasen</td><td>0</td></tr><tr><td>Mikrometastasen</td><td>1</td></tr><tr><td>ITC</td><td>0</td></tr><tr><td>Größte Metastasenausdehnung</td><td>1,2 mm</td></tr><tr><td>Extranodale Infiltration</td><td>Nicht vorhanden</td></tr></tbody></table><h4>Biomarker</h4><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>ER</td><td>Positiv (90%, stark)</td></tr><tr><td>PR</td><td>Positiv (60%, mäßig)</td></tr><tr><td>HER2 (IHC)</td><td>1+</td></tr><tr><td>HER2 (ISH)</td><td>Nicht amplifiziert</td></tr><tr><td>HER2-Gesamtstatus</td><td>Negativ</td></tr><tr><td>Ki-67</td><td>15%</td></tr></tbody></table><h4>Weitere Befunde</h4><table border=\"1\" cellpadding=\"4\" cellspacing=\"0\"><tbody><tr><td>Lymphgefäßinvasion</td><td>Nicht nachgewiesen</td></tr><tr><td>Mikrokalzifikationen</td><td>In DCIS assoziiert</td></tr></tbody></table><h4>TNM-Staging</h4><p><b>pT1c pN1mi(sn)</b></p><p><b>Kommentar:</b> Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. SLN #1 mit Mikrometastase (1,2 mm), erst in Paraffinschnittstufen nachgewiesen (Schnellschnitt war tumorfrei). Keine extranodale Infiltration. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</p></div>"
        },
        "entry" : [{
          "reference" : "DiagnosticReport/IntegratedReport"
        }]
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Patient/Patient4",
    "resource" : {
      "resourceType" : "Patient",
      "id" : "Patient4",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_Patient4\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Patient Patient4</b></p><a name=\"Patient4\"> </a><a name=\"hcPatient4\"> </a><p style=\"border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</p><hr/></div>"
      },
      "identifier" : [{
        "system" : "http://example.hospital.de/patient-ids",
        "value" : "PAT-2025-105"
      }],
      "name" : [{
        "family" : "Becker",
        "given" : ["Sabine"]
      }],
      "gender" : "female",
      "birthDate" : "1971-03-15"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Organization/PathologyLabOrganization",
    "resource" : {
      "resourceType" : "Organization",
      "id" : "PathologyLabOrganization",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_PathologyLabOrganization\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization PathologyLabOrganization</b></p><a name=\"PathologyLabOrganization\"> </a><a name=\"hcPathologyLabOrganization\"> </a><p><b>identifier</b>: <code>http://example.hospital.de/organization-ids</code>/ORG-PATH-001</p><p><b>name</b>: Institut für Pathologie</p></div>"
      },
      "identifier" : [{
        "system" : "http://example.hospital.de/organization-ids",
        "value" : "ORG-PATH-001"
      }],
      "name" : "Institut für Pathologie"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Practitioner/PathologistPractitioner",
    "resource" : {
      "resourceType" : "Practitioner",
      "id" : "PathologistPractitioner",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Practitioner_PathologistPractitioner\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Practitioner PathologistPractitioner</b></p><a name=\"PathologistPractitioner\"> </a><a name=\"hcPathologistPractitioner\"> </a><p><b>identifier</b>: <code>http://example.hospital.de/practitioner-ids</code>/PATH-001</p><p><b>name</b>: Elisabeth Hoffmann </p><h3>Qualifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 394595002}\">Pathology</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "http://example.hospital.de/practitioner-ids",
        "value" : "PATH-001"
      }],
      "name" : [{
        "family" : "Hoffmann",
        "given" : ["Elisabeth"],
        "prefix" : ["Dr."]
      }],
      "qualification" : [{
        "code" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "394595002",
            "display" : "Pathology"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Practitioner/BreastSurgeonPractitioner",
    "resource" : {
      "resourceType" : "Practitioner",
      "id" : "BreastSurgeonPractitioner",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Practitioner_BreastSurgeonPractitioner\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Practitioner BreastSurgeonPractitioner</b></p><a name=\"BreastSurgeonPractitioner\"> </a><a name=\"hcBreastSurgeonPractitioner\"> </a><p><b>identifier</b>: <code>http://example.hospital.de/practitioner-ids</code>/GYN-001</p><p><b>name</b>: Thomas Richter </p><h3>Qualifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 394586005}\">Gynecology</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "http://example.hospital.de/practitioner-ids",
        "value" : "GYN-001"
      }],
      "name" : [{
        "family" : "Richter",
        "given" : ["Thomas"],
        "prefix" : ["Prof. Dr."]
      }],
      "qualification" : [{
        "code" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "394586005",
            "display" : "Gynecology"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Encounter/IntegratedEncounter",
    "resource" : {
      "resourceType" : "Encounter",
      "id" : "IntegratedEncounter",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Encounter_IntegratedEncounter\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Encounter IntegratedEncounter</b></p><a name=\"IntegratedEncounter\"> </a><a name=\"hcIntegratedEncounter\"> </a><p><b>identifier</b>: <code>http://example.hospital.de/encounters</code>/E_25_300</p><p><b>status</b>: Finished</p><p><b>class</b>: [not stated]: IMP (IMP)</p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p></div>"
      },
      "identifier" : [{
        "system" : "http://example.hospital.de/encounters",
        "value" : "E_25_300"
      }],
      "status" : "finished",
      "class" : {
        "code" : "IMP"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Condition/IntegratedDiagnosisConfirmed",
    "resource" : {
      "resourceType" : "Condition",
      "id" : "IntegratedDiagnosisConfirmed",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/StructureDefinition/Diagnose|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Condition_IntegratedDiagnosisConfirmed\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Condition IntegratedDiagnosisConfirmed</b></p><a name=\"IntegratedDiagnosisConfirmed\"> </a><a name=\"hcIntegratedDiagnosisConfirmed\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.molgen@2026.0.4&amp;canonical=https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/StructureDefinition/Diagnose\">MII PR Diagnose Condition</a> version: 2026.0.0</p></div><p><b>clinicalStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/condition-clinical active}\">Active</span></p><p><b>verificationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/condition-ver-status confirmed}\">Confirmed</span></p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/condition-category encounter-diagnosis}\">Encounter Diagnosis</span></p><p><b>code</b>: <span title=\"Codes:{http://fhir.de/CodeSystem/bfarm/icd-10-gm C50.5}\">Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>encounter</b>: <a href=\"Encounter-IntegratedEncounter.html\">Encounter: identifier = http://example.hospital.de/encounters#E_25_300; status = finished; class = IMP (IMP)</a></p><p><b>onset</b>: 2025-01-15</p><p><b>recordedDate</b>: 2025-02-05</p><p><b>note</b>: </p><blockquote><div><p>Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links mit SLN-Biopsie Axilla indiziert.</p>\n</div></blockquote></div>"
      },
      "clinicalStatus" : {
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/condition-clinical",
          "code" : "active"
        }]
      },
      "verificationStatus" : {
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/condition-ver-status",
          "code" : "confirmed"
        }]
      },
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/condition-category",
          "code" : "encounter-diagnosis"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
          "version" : "2025",
          "code" : "C50.5",
          "display" : "Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "encounter" : {
        "reference" : "Encounter/IntegratedEncounter"
      },
      "onsetDateTime" : "2025-01-15",
      "recordedDate" : "2025-02-05",
      "note" : [{
        "text" : "Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links mit SLN-Biopsie Axilla indiziert."
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/ServiceRequest/IntegratedReportRequest",
    "resource" : {
      "resourceType" : "ServiceRequest",
      "id" : "IntegratedReportRequest",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-service-request|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ServiceRequest_IntegratedReportRequest\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ServiceRequest IntegratedReportRequest</b></p><a name=\"IntegratedReportRequest\"> </a><a name=\"hcIntegratedReportRequest\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-service-request\">MII PR Patho Service Request</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/PATH-RPT-2025-300</p><p><b>status</b>: Completed</p><p><b>intent</b>: Order</p><p><b>category</b>: <span title=\"Codes:{http://snomed.info/sct 726007}\">Pathology consultation, comprehensive, records and specimen with report (procedure)</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 60568-3}\">Pathology synoptic report</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>encounter</b>: <a href=\"Encounter-IntegratedEncounter.html\">Encounter: identifier = http://example.hospital.de/encounters#E_25_300; status = finished; class = IMP (IMP)</a></p><p><b>requester</b>: <a href=\"Practitioner-BreastSurgeonPractitioner.html\">Practitioner Thomas Richter </a></p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>reasonCode</b>: <span title=\"Codes:{http://snomed.info/sct 254837009}\">Malignant neoplasm of breast (disorder)</span></p><p><b>supportingInfo</b>: </p><ul><li><a href=\"Condition-IntegratedDiagnosisConfirmed.html\">Condition Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse</a></li><li><a href=\"DiagnosticReport-IntegratedImagingReport.html\">Diagnostic Report for 'MG Breast Screening' for '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href=\"Observation-IntegratedCancerHistory.html\">Observation Personal history of primary malignant neoplasm of breast (situation)</a></li><li><a href=\"Observation-IntegratedPriorTherapy.html\">Observation Cancer treatment --preoperative</a></li><li><a href=\"Observation-IntegratedRadiologicalExtent.html\">Observation Lesion size, largest dimension (observable entity)</a></li><li><a href=\"Observation-IntegratedSpecimenMarking.html\">Observation Insertion of marker into breast using X-ray guidance (procedure)</a></li><li><a href=\"Observation-IntegratedSpecimenRadiographyClinical.html\">Observation 80865008|Specimen mammography|:363702006|Has focus|=185008008|Medical reports sent|</a></li><li><a href=\"Observation-IntegratedGeneticPredisposition.html\">Observation Diathesis, function (observable entity)</a></li></ul><p><b>specimen</b>: </p><ul><li><a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></li><li><a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></li></ul></div>"
      },
      "identifier" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "PLAC",
            "display" : "Placer Identifier"
          }]
        },
        "system" : "http://example.hospital.de/serviceRequest",
        "value" : "PATH-RPT-2025-300"
      }],
      "status" : "completed",
      "intent" : "order",
      "category" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "726007",
          "display" : "Pathology consultation, comprehensive, records and specimen with report (procedure)"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "60568-3",
          "display" : "Pathology synoptic report"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "encounter" : {
        "reference" : "Encounter/IntegratedEncounter"
      },
      "requester" : {
        "reference" : "Practitioner/BreastSurgeonPractitioner"
      },
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "reasonCode" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "254837009",
          "display" : "Malignant neoplasm of breast (disorder)"
        }]
      }],
      "supportingInfo" : [{
        "reference" : "Condition/IntegratedDiagnosisConfirmed"
      },
      {
        "reference" : "DiagnosticReport/IntegratedImagingReport"
      },
      {
        "reference" : "Observation/IntegratedCancerHistory"
      },
      {
        "reference" : "Observation/IntegratedPriorTherapy"
      },
      {
        "reference" : "Observation/IntegratedRadiologicalExtent"
      },
      {
        "reference" : "Observation/IntegratedSpecimenMarking"
      },
      {
        "reference" : "Observation/IntegratedSpecimenRadiographyClinical"
      },
      {
        "reference" : "Observation/IntegratedGeneticPredisposition"
      }],
      "specimen" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/DiagnosticReport/IntegratedImagingReport",
    "resource" : {
      "resourceType" : "DiagnosticReport",
      "id" : "IntegratedImagingReport",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_IntegratedImagingReport\"> </a><p class=\"res-header-id\"><b>Generated Narrative: DiagnosticReport IntegratedImagingReport</b></p><a name=\"IntegratedImagingReport\"> </a><a name=\"hcIntegratedImagingReport\"> </a><h2><span title=\"Codes:{http://loinc.org 24606-6}\">MG Breast Screening</span> (<span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 RAD}\">Radiology</span>) </h2><table class=\"grid\"><tr><td>Subject</td><td>Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</td></tr><tr><td>When For</td><td>2025-01-08</td></tr></table><p><b>Report Details</b></p><p>BI-RADS 4b: Herdbefund linke Brust, unterer äußerer Quadrant, 5 Uhr, 5 cm von Mamille. Radiologische Ausdehnung ca. 15 mm. Mammografie und Ultraschall. Klinisch unauffällige Axilla (cN0). Indikation zur BET mit SLN-Biopsie.</p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/v2-0074",
          "code" : "RAD",
          "display" : "Radiology"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "24606-6",
          "display" : "MG Breast Screening"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-01-08",
      "conclusion" : "BI-RADS 4b: Herdbefund linke Brust, unterer äußerer Quadrant, 5 Uhr, 5 cm von Mamille. Radiologische Ausdehnung ca. 15 mm. Mammografie und Ultraschall. Klinisch unauffällige Axilla (cN0). Indikation zur BET mit SLN-Biopsie."
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedCancerHistory",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedCancerHistory",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedCancerHistory\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedCancerHistory</b></p><a name=\"IntegratedCancerHistory\"> </a><a name=\"hcIntegratedCancerHistory\"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 415076002}\">Brustkrebsvorgeschichte</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title=\"Codes:\">Ersterkrankung</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "415076002",
          "display" : "Personal history of primary malignant neoplasm of breast (situation)"
        }],
        "text" : "Brustkrebsvorgeschichte"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "valueCodeableConcept" : {
        "text" : "Ersterkrankung"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedPriorTherapy",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedPriorTherapy",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedPriorTherapy\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedPriorTherapy</b></p><a name=\"IntegratedPriorTherapy\"> </a><a name=\"hcIntegratedPriorTherapy\"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 81167-9}\">Vorchirurgische Therapie bei invasivem Karzinom</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 373067005}\">Keine neoadjuvante Therapie</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "81167-9",
          "display" : "Cancer treatment --preoperative"
        }],
        "text" : "Vorchirurgische Therapie bei invasivem Karzinom"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "373067005",
          "display" : "No (qualifier value)"
        }],
        "text" : "Keine neoadjuvante Therapie"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedRadiologicalExtent",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedRadiologicalExtent",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedRadiologicalExtent\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedRadiologicalExtent</b></p><a name=\"IntegratedRadiologicalExtent\"> </a><a name=\"hcIntegratedRadiologicalExtent\"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 396361002}\">Radiologische Ausdehnung</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: 15 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "396361002",
          "display" : "Lesion size, largest dimension (observable entity)"
        }],
        "text" : "Radiologische Ausdehnung"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "valueQuantity" : {
        "value" : 15,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedSpecimenMarking",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedSpecimenMarking",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedSpecimenMarking\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedSpecimenMarking</b></p><a name=\"IntegratedSpecimenMarking\"> </a><a name=\"hcIntegratedSpecimenMarking\"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 836381000000102}\">Befundmarkierung</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title=\"Codes:\">Drahthäkchen</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "836381000000102",
          "display" : "Insertion of marker into breast using X-ray guidance (procedure)"
        }],
        "text" : "Befundmarkierung"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "valueCodeableConcept" : {
        "text" : "Drahthäkchen"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedSpecimenRadiographyClinical",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedSpecimenRadiographyClinical",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedSpecimenRadiographyClinical\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedSpecimenRadiographyClinical</b></p><a name=\"IntegratedSpecimenRadiographyClinical\"> </a><a name=\"hcIntegratedSpecimenRadiographyClinical\"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 80865008:363702006=185008008}\">Präparateradiographie beigelegt</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 52101004}\">Ja, beigelegt</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "80865008:363702006=185008008",
          "display" : "80865008|Specimen mammography|:363702006|Has focus|=185008008|Medical reports sent|"
        }],
        "text" : "Präparateradiographie beigelegt"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "52101004",
          "display" : "Present (qualifier value)"
        }],
        "text" : "Ja, beigelegt"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedGeneticPredisposition",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedGeneticPredisposition",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedGeneticPredisposition\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedGeneticPredisposition</b></p><a name=\"IntegratedGeneticPredisposition\"> </a><a name=\"hcIntegratedGeneticPredisposition\"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 76522002}\">Genetische Prädisposition</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 261665006}\">Nicht bekannt</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "76522002",
          "display" : "Diathesis, function (observable entity)"
        }],
        "text" : "Genetische Prädisposition"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "261665006",
          "display" : "Unknown (qualifier value)"
        }],
        "text" : "Nicht bekannt"
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/DiagnosticReport/IntegratedReport",
    "resource" : {
      "resourceType" : "DiagnosticReport",
      "id" : "IntegratedReport",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-report|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_IntegratedReport\"> </a><p class=\"res-header-id\"><b>Generated Narrative: DiagnosticReport IntegratedReport</b></p><a name=\"IntegratedReport\"> </a><a name=\"hcIntegratedReport\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-report\">MII PR Patho Report</a> version: 2026.0.0</p></div><h2><span title=\"Codes:{http://loinc.org 60568-3}\">Pathology Synoptic report</span> (<span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 SP}\">Surgical Pathology</span>) </h2><table class=\"grid\"><tr><td>Subject</td><td>Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</td></tr><tr><td>When For</td><td>2025-02-10 14:00:00+0100</td></tr><tr><td>Reported</td><td>2025-02-10 17:00:00+0100</td></tr><tr><td>Performer</td><td> <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></td></tr><tr><td>Identifier</td><td> Accession ID/E_25_300</td></tr></table><p><b>Report Details</b></p><table class=\"grid\"><tr><td><b>Code</b></td><td><b>Value</b></td><td><b>Flags</b></td><td><b>When For</b></td></tr><tr><td><a href=\"Observation-IntegratedMacroscopicGrouper.html\"><span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></a></td><td/><td>Final</td><td>2025-02-06 08:30:00+0100</td></tr><tr><td><a href=\"Observation-IntegratedDiagnosticConclusionGrouper.html\"><span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></a></td><td/><td>Final</td><td>2025-02-10</td></tr></table><p>Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c pN1mi(sn), Nottingham Grad 2 (Score 6: Tubuli 3, Kernpleomorphie 2, Mitosen 1). Begleitendes DCIS, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen. Alle Resektionsränder tumorfrei (invasiv 5 mm, DCIS 3 mm). Keine LVI. ER+ (90%), PR+ (60%), HER2 1+ (nicht amplifiziert), Ki-67 15%. SLN 1/2 befallen (Mikrometastase 1,2 mm in SLN #1), keine extranodale Infiltration.</p></div>"
      },
      "identifier" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }]
        },
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      }],
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/v2-0074",
          "code" : "SP",
          "display" : "Surgical Pathology"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "60568-3",
          "display" : "Pathology Synoptic report"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10T14:00:00+01:00",
      "issued" : "2025-02-10T17:00:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "specimen" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      {
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
      },
      {
        "reference" : "Specimen/IntegratedBETSpecimenBlock02"
      },
      {
        "reference" : "Specimen/IntegratedBETSpecimenBlock03"
      },
      {
        "reference" : "Specimen/IntegratedBETSpecimenBlock04"
      },
      {
        "reference" : "Specimen/IntegratedBETSpecimenBlock05"
      },
      {
        "reference" : "Specimen/IntegratedBETSpecimenBlock06"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideHE02"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideER01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlidePR01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideHER2IHC01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideKi67-01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideCK18-01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlidep40-01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideECad-01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideBlock02-HE01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideBlock02-HE02"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideRR-Superior-HE01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideRR-Inferior-HE01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideRR-Medial-HE01"
      },
      {
        "reference" : "Specimen/IntegratedBETSlideRR-Lateral-HE01"
      },
      {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      {
        "reference" : "Specimen/IntegratedSLNSpecimenBlock01"
      },
      {
        "reference" : "Specimen/IntegratedSLNSpecimenBlock02"
      },
      {
        "reference" : "Specimen/IntegratedSLNSlideHE01"
      },
      {
        "reference" : "Specimen/IntegratedSLNSlideHE02"
      },
      {
        "reference" : "Specimen/IntegratedSLNSlideHE03"
      },
      {
        "reference" : "Specimen/IntegratedSLNSlideHE04"
      }],
      "result" : [{
        "reference" : "Observation/IntegratedMacroscopicGrouper"
      },
      {
        "reference" : "Observation/IntegratedDiagnosticConclusionGrouper"
      }],
      "conclusion" : "Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c pN1mi(sn), Nottingham Grad 2 (Score 6: Tubuli 3, Kernpleomorphie 2, Mitosen 1). Begleitendes DCIS, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen. Alle Resektionsränder tumorfrei (invasiv 5 mm, DCIS 3 mm). Keine LVI. ER+ (90%), PR+ (60%), HER2 1+ (nicht amplifiziert), Ki-67 15%. SLN 1/2 befallen (Mikrometastase 1,2 mm in SLN #1), keine extranodale Infiltration."
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenPart",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenPart",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenPart\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenPart</b></p><a name=\"IntegratedBETSpecimenPart\"> </a><a name=\"hcIntegratedBETSpecimenPart\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/OP25_300_A, Filler Identifier/E_25_300_A</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 397199005}\">Specimen from breast obtained by excision (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>request</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collector</b></td><td><b>Collected[x]</b></td><td><b>Method</b></td><td><b>BodySite</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Practitioner-BreastSurgeonPractitioner.html\">Practitioner Thomas Richter </a></td><td>2025-02-05 10:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 237371007}\">Wide local excision of breast lesion (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 33564002}\">Structure of lower outer quadrant of breast (body structure)</span></td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 434746001}\">Specimen vial (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 434162003}\">Neutral buffered formalin (substance)</span></td></tr></table><p><b>note</b>: </p><blockquote><div><p>BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</p>\n</div></blockquote></div>"
      },
      "identifier" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "PLAC"
          }]
        },
        "system" : "https://senologie.example-hospital.de/fhir/specimen/placer",
        "value" : "OP25_300_A"
      },
      {
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "FILL"
          }]
        },
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "397199005",
          "display" : "Specimen from breast obtained by excision (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "request" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "collection" : {
        "collector" : {
          "reference" : "Practitioner/BreastSurgeonPractitioner"
        },
        "collectedDateTime" : "2025-02-05T10:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "237371007",
            "display" : "Wide local excision of breast lesion (procedure)"
          }]
        },
        "bodySite" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "33564002",
            "display" : "Structure of lower outer quadrant of breast (body structure)"
          }]
        }
      },
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434746001",
            "display" : "Specimen vial (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434162003",
            "display" : "Neutral buffered formalin (substance)"
          }]
        }
      }],
      "note" : [{
        "text" : "BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm."
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenBlock01",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenBlock01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock01</b></p><a name=\"IntegratedBETSpecimenBlock01\"> </a><a name=\"hcIntegratedBETSpecimenBlock01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe III</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:00:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_1"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe III",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:00:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock02",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenBlock02",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenBlock02\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock02</b></p><a name=\"IntegratedBETSpecimenBlock02\"> </a><a name=\"hcIntegratedBETSpecimenBlock02\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_2</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:10:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe V</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:10:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_2"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:10:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe V",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:10:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock03",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenBlock03",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenBlock03\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock03</b></p><a name=\"IntegratedBETSpecimenBlock03\"> </a><a name=\"hcIntegratedBETSpecimenBlock03\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_3</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:20:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR superior</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:20:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_3"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:20:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - RR superior",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:20:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock04",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenBlock04",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenBlock04\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock04</b></p><a name=\"IntegratedBETSpecimenBlock04\"> </a><a name=\"hcIntegratedBETSpecimenBlock04\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_4</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR inferior</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:30:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_4"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - RR inferior",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:30:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock05",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenBlock05",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenBlock05\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock05</b></p><a name=\"IntegratedBETSpecimenBlock05\"> </a><a name=\"hcIntegratedBETSpecimenBlock05\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_5</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:40:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR medial, Scheibe I</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:40:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_5"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:40:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - RR medial, Scheibe I",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:40:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock06",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSpecimenBlock06",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSpecimenBlock06\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock06</b></p><a name=\"IntegratedBETSpecimenBlock06\"> </a><a name=\"hcIntegratedBETSpecimenBlock06\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_6</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:50:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR lateral, Scheibe VIII</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:50:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_6"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:50:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - RR lateral, Scheibe VIII",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:50:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideHE01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideHE01",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideHE01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideHE01</b></p><a name=\"IntegratedBETSlideHE01\"> </a><a name=\"hcIntegratedBETSlideHE01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_1_1_HE_01"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung (Schnittstufe 1)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideHE02",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideHE02",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideHE02\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideHE02</b></p><a name=\"IntegratedBETSlideHE02\"> </a><a name=\"hcIntegratedBETSlideHE02\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_1_1_HE_02"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung (Schnittstufe 2)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideER01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideER01",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideER01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideER01</b></p><a name=\"IntegratedBETSlideER01\"> </a><a name=\"hcIntegratedBETSlideER01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_ER_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: ER-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstanceER.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
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        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
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      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
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      "collection" : {
        "collectedDateTime" : "2025-02-06T09:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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        }],
        "description" : "Schnittherstellung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
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        },
        "timeDateTime" : "2025-02-06T09:30:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "ER-Immunhistochemie",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "117617002",
            "display" : "Immunohistochemistry procedure (procedure)"
          }]
        },
        "additive" : [{
          "reference" : "Substance/IntegratedSubstanceER"
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        "timeDateTime" : "2025-02-06T10:00:00+01:00"
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      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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        },
        "additiveCodeableConcept" : {
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            "system" : "http://snomed.info/sct",
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    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlidePR01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlidePR01",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlidePR01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlidePR01</b></p><a name=\"IntegratedBETSlidePR01\"> </a><a name=\"hcIntegratedBETSlidePR01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_PR_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: PR-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstancePR.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_1_1_PR_01"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:30:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "PR-Immunhistochemie",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "117617002",
            "display" : "Immunohistochemistry procedure (procedure)"
          }]
        },
        "additive" : [{
          "reference" : "Substance/IntegratedSubstancePR"
        }],
        "timeDateTime" : "2025-02-06T10:00:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideHER2IHC01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideHER2IHC01",
      "meta" : {
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        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideHER2IHC01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideHER2IHC01</b></p><a name=\"IntegratedBETSlideHER2IHC01\"> </a><a name=\"hcIntegratedBETSlideHER2IHC01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_HER2_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HER2-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstanceHER2IHC.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
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      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
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            "high" : {
              "value" : 25,
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              "system" : "http://unitsofmeasure.org",
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        "procedure" : {
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            "system" : "http://snomed.info/sct",
            "code" : "434472006",
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        },
        "timeDateTime" : "2025-02-06T09:30:00+01:00"
      },
      {
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          "valueRange" : {
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HER2-Immunhistochemie",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "117617002",
            "display" : "Immunohistochemistry procedure (procedure)"
          }]
        },
        "additive" : [{
          "reference" : "Substance/IntegratedSubstanceHER2IHC"
        }],
        "timeDateTime" : "2025-02-06T10:00:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideKi67-01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideKi67-01",
      "meta" : {
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        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideKi67-01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideKi67-01</b></p><a name=\"IntegratedBETSlideKi67-01\"> </a><a name=\"hcIntegratedBETSlideKi67-01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_Ki67_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Ki-67-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstanceKi67.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "identifier" : [{
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        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
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      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
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      "collection" : {
        "collectedDateTime" : "2025-02-06T09:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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        }],
        "description" : "Schnittherstellung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
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        },
        "timeDateTime" : "2025-02-06T09:30:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
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              "system" : "http://unitsofmeasure.org",
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Ki-67-Immunhistochemie",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "117617002",
            "display" : "Immunohistochemistry procedure (procedure)"
          }]
        },
        "additive" : [{
          "reference" : "Substance/IntegratedSubstanceKi67"
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      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideCK18-01",
    "resource" : {
      "resourceType" : "Specimen",
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      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
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      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideCK18-01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideCK18-01</b></p><a name=\"IntegratedBETSlideCK18-01\"> </a><a name=\"hcIntegratedBETSlideCK18-01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_CK18_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: CK18-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstanceCK18.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_1_1_CK18_01"
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      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:30:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "CK18-Immunhistochemie",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "117617002",
            "display" : "Immunohistochemistry procedure (procedure)"
          }]
        },
        "additive" : [{
          "reference" : "Substance/IntegratedSubstanceCK18"
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        "timeDateTime" : "2025-02-06T10:00:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
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  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlidep40-01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlidep40-01",
      "meta" : {
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      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlidep40-01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlidep40-01</b></p><a name=\"IntegratedBETSlidep40-01\"> </a><a name=\"hcIntegratedBETSlidep40-01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_p40_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: p40-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstancep40.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      },
      "status" : "available",
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        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
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      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
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        "method" : {
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            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
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            "high" : {
              "value" : 25,
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            "system" : "http://snomed.info/sct",
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            "display" : "Sectioning of tissue block (procedure)"
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        },
        "timeDateTime" : "2025-02-06T09:30:00+01:00"
      },
      {
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          "valueRange" : {
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "p40-Immunhistochemie",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "117617002",
            "display" : "Immunohistochemistry procedure (procedure)"
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        },
        "additive" : [{
          "reference" : "Substance/IntegratedSubstancep40"
        }],
        "timeDateTime" : "2025-02-06T10:00:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
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            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideECad-01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideECad-01",
      "meta" : {
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        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideECad-01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideECad-01</b></p><a name=\"IntegratedBETSlideECad-01\"> </a><a name=\"hcIntegratedBETSlideECad-01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_ECad_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: E-Cadherin-Immunhistochemie</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 117617002}\">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href=\"Substance-IntegratedSubstanceECadherin.html\">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "status" : "available",
      "type" : {
        "coding" : [{
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      "subject" : {
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      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock01"
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      "collection" : {
        "collectedDateTime" : "2025-02-06T09:30:00+01:00",
        "method" : {
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            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
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      },
      "processing" : [{
        "extension" : [{
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          "valueRange" : {
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      {
        "extension" : [{
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              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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          "reference" : "Substance/IntegratedSubstanceECadherin"
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      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideBlock02-HE01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideBlock02-HE01</b></p><a name=\"IntegratedBETSlideBlock02-HE01\"> </a><a name=\"hcIntegratedBETSlideBlock02-HE01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_2_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock02.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "accessionIdentifier" : {
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      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
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      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock02"
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      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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        }],
        "description" : "Schnittherstellung (Schnittstufe 1)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
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        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
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              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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        }],
        "description" : "HE-Färbung",
        "procedure" : {
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            "display" : "Hematoxylin and eosin stain method (procedure)"
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        "timeDateTime" : "2025-02-06T09:15:00+01:00"
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      "container" : [{
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  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideBlock02-HE02",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedBETSlideBlock02-HE02",
      "meta" : {
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        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
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      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideBlock02-HE02\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideBlock02-HE02</b></p><a name=\"IntegratedBETSlideBlock02-HE02\"> </a><a name=\"hcIntegratedBETSlideBlock02-HE02\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_2_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock02.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      },
      "processing" : [{
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    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedBETSlideRR-Superior-HE01",
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      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideRR-Superior-HE01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideRR-Superior-HE01</b></p><a name=\"IntegratedBETSlideRR-Superior-HE01\"> </a><a name=\"hcIntegratedBETSlideRR-Superior-HE01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_3_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock03.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
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      "processing" : [{
        "extension" : [{
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      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedBETSlideRR-Lateral-HE01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedBETSlideRR-Lateral-HE01</b></p><a name=\"IntegratedBETSlideRR-Lateral-HE01\"> </a><a name=\"hcIntegratedBETSlideRR-Lateral-HE01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_6_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedBETSpecimenBlock06.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_6; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_A_6_1_HE_01"
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      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedBETSpecimenBlock06"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSpecimenPart",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSpecimenPart",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSpecimenPart\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSpecimenPart</b></p><a name=\"IntegratedSLNSpecimenPart\"> </a><a name=\"hcIntegratedSLNSpecimenPart\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/OP25_300_B, Filler Identifier/E_25_300_B</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 258589002}\">Lymph node specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>request</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collector</b></td><td><b>Collected[x]</b></td><td><b>Method</b></td><td><b>BodySite</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Practitioner-BreastSurgeonPractitioner.html\">Practitioner Thomas Richter </a></td><td>2025-02-05 10:30:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 396487001}\">Sentinel lymph node biopsy (procedure)</span></td><td><span title=\"Codes:{http://snomed.info/sct 68171009}\">Axillary lymph node structure (body structure)</span></td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 434746001}\">Specimen vial (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 434162003}\">Neutral buffered formalin (substance)</span></td></tr></table><p><b>note</b>: </p><blockquote><div><p>Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</p>\n</div></blockquote></div>"
      },
      "identifier" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "PLAC"
          }]
        },
        "system" : "https://senologie.example-hospital.de/fhir/specimen/placer",
        "value" : "OP25_300_B"
      },
      {
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "FILL"
          }]
        },
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "258589002",
          "display" : "Lymph node specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "request" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "collection" : {
        "collector" : {
          "reference" : "Practitioner/BreastSurgeonPractitioner"
        },
        "collectedDateTime" : "2025-02-05T10:30:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "396487001",
            "display" : "Sentinel lymph node biopsy (procedure)"
          }]
        },
        "bodySite" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "68171009",
            "display" : "Axillary lymph node structure (body structure)"
          }]
        }
      },
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434746001",
            "display" : "Specimen vial (physical object)"
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        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434162003",
            "display" : "Neutral buffered formalin (substance)"
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        }
      }],
      "note" : [{
        "text" : "Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet."
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSpecimenBlock01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSpecimenBlock01",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSpecimenBlock01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSpecimenBlock01</b></p><a name=\"IntegratedSLNSpecimenBlock01\"> </a><a name=\"hcIntegratedSLNSpecimenBlock01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_1</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - SLN #1 (halbiert)</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:00:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B_1"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - SLN #1 (halbiert)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:00:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSpecimenBlock02",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSpecimenBlock02",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSpecimenBlock02\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSpecimenBlock02</b></p><a name=\"IntegratedSLNSpecimenBlock02\"> </a><a name=\"hcIntegratedSLNSpecimenBlock02\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_2</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 1201985008}\">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 08:10:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 787377000}\">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Zuschnitt und Paraffineinbettung - SLN #2 (halbiert)</td><td><span title=\"Codes:{http://snomed.info/sct 787376009}\">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:10:00+0100</td></tr></table><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 706053007}\">General specimen container (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 311731000}\">Paraffin wax (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B_2"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1201985008",
          "display" : "Tissue block specimen (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T08:10:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787377000",
            "display" : "Gross examination and sampling of tissue specimen (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 2,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 8,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Zuschnitt und Paraffineinbettung - SLN #2 (halbiert)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "787376009",
            "display" : "Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T08:10:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "706053007",
            "display" : "General specimen container (physical object)"
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        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "311731000",
            "display" : "Paraffin wax (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE01",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSlideHE01",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSlideHE01\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSlideHE01</b></p><a name=\"IntegratedSLNSlideHE01\"> </a><a name=\"hcIntegratedSLNSlideHE01\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_1_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedSLNSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B_1_1_HE_01"
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      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedSLNSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung (Schnittstufe 1)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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      }]
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  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE02",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSlideHE02",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
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      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSlideHE02\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSlideHE02</b></p><a name=\"IntegratedSLNSlideHE02\"> </a><a name=\"hcIntegratedSLNSlideHE02\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_1_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedSLNSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B_1_1_HE_02"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedSLNSpecimenBlock01"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
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        }],
        "description" : "Schnittherstellung (Schnittstufe 2)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
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        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
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      {
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            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
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        },
        "additiveCodeableConcept" : {
          "coding" : [{
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            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
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      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE03",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSlideHE03",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSlideHE03\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSlideHE03</b></p><a name=\"IntegratedSLNSlideHE03\"> </a><a name=\"hcIntegratedSLNSlideHE03\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_2_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedSLNSpecimenBlock02.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B_2_1_HE_01"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedSLNSpecimenBlock02"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung (Schnittstufe 1)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE04",
    "resource" : {
      "resourceType" : "Specimen",
      "id" : "IntegratedSLNSlideHE04",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0",
        "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"]
      },
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_IntegratedSLNSlideHE04\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen IntegratedSLNSlideHE04</b></p><a name=\"IntegratedSLNSlideHE04\"> </a><a name=\"hcIntegratedSLNSlideHE04\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen\">MII PR Patho Specimen</a> version: 2026.0.0, <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore\">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_2_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 430856003}\">Tissue section (specimen)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href=\"Specimen-IntegratedSLNSpecimenBlock02.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style=\"display: none\">*</td><td>2025-02-06 09:00:00+0100</td><td><span title=\"Codes:{http://snomed.info/sct 13283003}\">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 434472006}\">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title=\"Codes:{http://snomed.info/sct 104210008}\">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 433466003}\">Microscope slide (physical object)</span></td><td><span title=\"Codes:{http://snomed.info/sct 430862008}\">Microscope slide mounting medium (substance)</span></td></tr></table></div>"
      },
      "identifier" : [{
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300_B_2_1_HE_02"
      }],
      "accessionIdentifier" : {
        "system" : "https://pathologie.example-hospital.de/fhir/fn/befundbericht",
        "value" : "E_25_300"
      },
      "status" : "available",
      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "430856003",
          "display" : "Tissue section (specimen)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "parent" : [{
        "reference" : "Specimen/IntegratedSLNSpecimenBlock02"
      }],
      "collection" : {
        "collectedDateTime" : "2025-02-06T09:00:00+01:00",
        "method" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "13283003",
            "display" : "Tissue processing technique (procedure)"
          }]
        }
      },
      "processing" : [{
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "Schnittherstellung (Schnittstufe 2)",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "434472006",
            "display" : "Sectioning of tissue block (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:00:00+01:00"
      },
      {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 20,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 25,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }],
        "description" : "HE-Färbung",
        "procedure" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "104210008",
            "display" : "Hematoxylin and eosin stain method (procedure)"
          }]
        },
        "timeDateTime" : "2025-02-06T09:15:00+01:00"
      }],
      "container" : [{
        "type" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "433466003",
            "display" : "Microscope slide (physical object)"
          }]
        },
        "additiveCodeableConcept" : {
          "coding" : [{
            "system" : "http://snomed.info/sct",
            "code" : "430862008",
            "display" : "Microscope slide mounting medium (substance)"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstanceER",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstanceER",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstanceER\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstanceER</b></p><a name=\"IntegratedSubstanceER\"> </a><a name=\"hcIntegratedSubstanceER\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: Estrogen Receptor (Dako Omnis)</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "Estrogen Receptor (Dako Omnis)"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstancePR",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstancePR",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstancePR\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstancePR</b></p><a name=\"IntegratedSubstancePR\"> </a><a name=\"hcIntegratedSubstancePR\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: Progesterone Receptor (Dako Omnis)</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "Progesterone Receptor (Dako Omnis)"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstanceHER2IHC",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstanceHER2IHC",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstanceHER2IHC\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstanceHER2IHC</b></p><a name=\"IntegratedSubstanceHER2IHC\"> </a><a name=\"hcIntegratedSubstanceHER2IHC\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: VENTANA HER2 (4B5), Roche</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "VENTANA HER2 (4B5), Roche"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstanceKi67",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstanceKi67",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstanceKi67\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstanceKi67</b></p><a name=\"IntegratedSubstanceKi67\"> </a><a name=\"hcIntegratedSubstanceKi67\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: Ki-67 Antigen (Dako Omnis)</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "Ki-67 Antigen (Dako Omnis)"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstanceCK18",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstanceCK18",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstanceCK18\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstanceCK18</b></p><a name=\"IntegratedSubstanceCK18\"> </a><a name=\"hcIntegratedSubstanceCK18\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: Cytokeratin 18 (DC10), Dako Omnis</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "Cytokeratin 18 (DC10), Dako Omnis"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstancep40",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstancep40",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstancep40\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstancep40</b></p><a name=\"IntegratedSubstancep40\"> </a><a name=\"hcIntegratedSubstancep40\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: p40 (BC28), Biocare Medical</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "p40 (BC28), Biocare Medical"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Substance/IntegratedSubstanceECadherin",
    "resource" : {
      "resourceType" : "Substance",
      "id" : "IntegratedSubstanceECadherin",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_IntegratedSubstanceECadherin\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Substance IntegratedSubstanceECadherin</b></p><a name=\"IntegratedSubstanceECadherin\"> </a><a name=\"hcIntegratedSubstanceECadherin\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance\">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}\">Chemical</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 45389009}\">Tissue stain (substance)</span></p><p><b>description</b>: E-Cadherin (NCH-38), Dako Omnis</p></div>"
      },
      "status" : "active",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/substance-category",
          "code" : "chemical",
          "display" : "Chemical"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "45389009",
          "display" : "Tissue stain (substance)"
        }]
      },
      "description" : "E-Cadherin (NCH-38), Dako Omnis"
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroscopicGrouper",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroscopicGrouper",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-macroscopic-grouper|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroscopicGrouper\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroscopicGrouper</b></p><a name=\"IntegratedMacroscopicGrouper\"> </a><a name=\"hcIntegratedMacroscopicGrouper\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-macroscopic-grouper\">MII PR Patho Macroscopic Grouper</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>hasMember</b>: </p><ul><li><a href=\"Observation-IntegratedMacroLength.html\">Observation Specimen size.maximum dimension in Breast tumor</a></li><li><a href=\"Observation-IntegratedMacroWidth.html\">Observation Specimen size additional dimension 1 in Breast tumor</a></li><li><a href=\"Observation-IntegratedMacroDepth.html\">Observation Specimen size additional dimension 2 in Breast tumor</a></li><li><a href=\"Observation-IntegratedMacroWeight.html\">Observation Specimen wt Tiss Qn</a></li><li><a href=\"Observation-IntegratedMacroQuadrant.html\">Observation Quadrant Breast</a></li><li><a href=\"Observation-IntegratedMacroClock.html\">Observation Radial position in breast [Angle] in Breast cancer specimen</a></li><li><a href=\"Observation-IntegratedMacroDistanceNipple.html\">Observation Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)</a></li><li><a href=\"Observation-IntegratedMacroBlockCount.html\">Observation Number of paraffin embedded tissue blocks examined from excised specimen (observable entity)</a></li><li><a href=\"Observation-IntegratedMacroSLN1Size.html\">Observation Length of tissue core(s)</a></li><li><a href=\"Observation-IntegratedMacroSLN2Size.html\">Observation Length of tissue core(s)</a></li></ul><p><b>derivedFrom</b>: </p><ul><li><a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li></ul></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "hasMember" : [{
        "reference" : "Observation/IntegratedMacroLength"
      },
      {
        "reference" : "Observation/IntegratedMacroWidth"
      },
      {
        "reference" : "Observation/IntegratedMacroDepth"
      },
      {
        "reference" : "Observation/IntegratedMacroWeight"
      },
      {
        "reference" : "Observation/IntegratedMacroQuadrant"
      },
      {
        "reference" : "Observation/IntegratedMacroClock"
      },
      {
        "reference" : "Observation/IntegratedMacroDistanceNipple"
      },
      {
        "reference" : "Observation/IntegratedMacroBlockCount"
      },
      {
        "reference" : "Observation/IntegratedMacroSLN1Size"
      },
      {
        "reference" : "Observation/IntegratedMacroSLN2Size"
      }],
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      },
      {
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroLength",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroLength",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroLength\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroLength</b></p><a name=\"IntegratedMacroLength\"> </a><a name=\"hcIntegratedMacroLength\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44629-4}\">ProbeGröße1</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 42 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title=\"Codes:{http://snomed.info/sct 76752008}\">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44629-4",
          "display" : "Specimen size.maximum dimension in Breast tumor"
        }],
        "text" : "ProbeGröße1"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 42,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "bodySite" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "76752008",
          "display" : "Breast structure (body structure)"
        }]
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroWidth",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroWidth",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroWidth\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroWidth</b></p><a name=\"IntegratedMacroWidth\"> </a><a name=\"hcIntegratedMacroWidth\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44630-2}\">ProbeGröße2</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 35 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title=\"Codes:{http://snomed.info/sct 76752008}\">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44630-2",
          "display" : "Specimen size additional dimension 1 in Breast tumor"
        }],
        "text" : "ProbeGröße2"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 35,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "bodySite" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "76752008",
          "display" : "Breast structure (body structure)"
        }]
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroDepth",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroDepth",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroDepth\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroDepth</b></p><a name=\"IntegratedMacroDepth\"> </a><a name=\"hcIntegratedMacroDepth\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44631-0}\">ProbeGröße3</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 18 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title=\"Codes:{http://snomed.info/sct 76752008}\">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44631-0",
          "display" : "Specimen size additional dimension 2 in Breast tumor"
        }],
        "text" : "ProbeGröße3"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 18,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "bodySite" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "76752008",
          "display" : "Breast structure (body structure)"
        }]
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroWeight",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroWeight",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroWeight\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroWeight</b></p><a name=\"IntegratedMacroWeight\"> </a><a name=\"hcIntegratedMacroWeight\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 29638-4}\">Gewicht der Probe</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 10 g<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p><p><b>bodySite</b>: <span title=\"Codes:{http://snomed.info/sct 76752008}\">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "29638-4",
          "display" : "Specimen wt Tiss Qn"
        }],
        "text" : "Gewicht der Probe"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 10,
        "unit" : "g",
        "system" : "http://unitsofmeasure.org",
        "code" : "g"
      },
      "bodySite" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "76752008",
          "display" : "Breast structure (body structure)"
        }]
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroQuadrant",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroQuadrant",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroQuadrant\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroQuadrant</b></p><a name=\"IntegratedMacroQuadrant\"> </a><a name=\"hcIntegratedMacroQuadrant\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 42799-7}\">Quadrantenlokalisaion</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 33564002}\">Unterer äußerer Quadrant</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "42799-7",
          "display" : "Quadrant Breast"
        }],
        "text" : "Quadrantenlokalisaion"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "33564002",
          "display" : "Structure of lower outer quadrant of breast (body structure)"
        }],
        "text" : "Unterer äußerer Quadrant"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroClock",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroClock",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroClock\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroClock</b></p><a name=\"IntegratedMacroClock\"> </a><a name=\"hcIntegratedMacroClock\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85332-5}, {http://snomed.info/sct 3980001000004105}\">Zifferblattlokalisation</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 5 o'clock<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{clock position} = '{clock position}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85332-5",
          "display" : "Radial position in breast [Angle] in Breast cancer specimen"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "3980001000004105",
          "display" : "Radial location of primary malignant neoplasm in excised breast specimen (observable entity)"
        }],
        "text" : "Zifferblattlokalisation"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 5,
        "unit" : "o'clock",
        "system" : "http://unitsofmeasure.org",
        "code" : "{clock position}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroDistanceNipple",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroDistanceNipple",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroDistanceNipple\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroDistanceNipple</b></p><a name=\"IntegratedMacroDistanceNipple\"> </a><a name=\"hcIntegratedMacroDistanceNipple\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1240401000}\">Abstand von der Mamille</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 50 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1240401000",
          "display" : "Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)"
        }],
        "text" : "Abstand von der Mamille"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 50,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroBlockCount",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroBlockCount",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroBlockCount\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroBlockCount</b></p><a name=\"IntegratedMacroBlockCount\"> </a><a name=\"hcIntegratedMacroBlockCount\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 3100001000004109}\">Anzahl Paraffinblöcke</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 6 Blöcke<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{blocks} = '{blocks}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22634-0"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "3100001000004109",
          "display" : "Number of paraffin embedded tissue blocks examined from excised specimen (observable entity)"
        }],
        "text" : "Anzahl Paraffinblöcke"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-06T08:30:00+01:00",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 6,
        "unit" : "Blöcke",
        "system" : "http://unitsofmeasure.org",
        "code" : "{blocks}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroSLN1Size",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroSLN1Size",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroSLN1Size\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroSLN1Size</b></p><a name=\"IntegratedMacroSLN1Size\"> </a><a name=\"hcIntegratedMacroSLN1Size\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22634-0}\">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44619-5}\">SLN #1 Größe</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 12 x 8 x 6 mm, Patentblau-markiert</p><p><b>bodySite</b>: <span title=\"Codes:{http://snomed.info/sct 68171009}\">Axillary lymph node structure (body structure)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenBlock01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
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        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedDiagnosticConclusionGrouper\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedDiagnosticConclusionGrouper</b></p><a name=\"IntegratedDiagnosticConclusionGrouper\"> </a><a name=\"hcIntegratedDiagnosticConclusionGrouper\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-diagnostic-conclusion-grouper\">MII PR Patho Diagnostic Conclusion Grouper</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>hasMember</b>: </p><ul><li><a href=\"Observation-IntegratedOperativeProcedure.html\">Observation Surgery procedure</a></li><li><a href=\"Observation-IntegratedMaterialType.html\">Observation Specimen type</a></li><li><a href=\"Observation-IntegratedLaterality.html\">Observation Specimen laterality (observable entity)</a></li><li><a href=\"Observation-IntegratedAttachedTissue.html\">Observation Body structure included in specimen [Anatomy] in Specimen</a></li><li><a href=\"Observation-IntegratedFocality.html\">Observation Qualitative distribution of primary malignant neoplasm of breast in excised breast specimen (observable entity)</a></li><li><a href=\"Observation-IntegratedMaxDiameterInvasive.html\">Observation Inv comp size max dim BT</a></li><li><a href=\"Observation-IntegratedMaxOverallDiameter.html\">Observation Size.maximum dimension in Tumor</a></li><li><a href=\"Observation-IntegratedHistologicalType.html\">Observation Histo type BT</a></li><li><a href=\"Observation-IntegratedMorphologyFreeText.html\">Observation Histology type in Cancer specimen Narrative</a></li><li><a href=\"Observation-IntegratedNottinghamGrade.html\">Observation Histologic grade [Score] in Breast cancer specimen by Nottingham</a></li><li><a href=\"Observation-IntegratedTubuleScore.html\">Observation Glandular differentiation [Score] in Breast cancer specimen by Nottingham</a></li><li><a href=\"Observation-IntegratedNuclearPleomorphism.html\">Observation Nuclear pleomorphism in Breast tumor by Nottingham</a></li><li><a href=\"Observation-IntegratedMitosisCount.html\">Observation Number of mitoses per 10 high power fields (observable entity)</a></li><li><a href=\"Observation-IntegratedMitoticRateScore.html\">Observation Mitotic rate [Score] in Breast cancer specimen by Nottingham</a></li><li><a href=\"Observation-IntegratedElstonEllisScore.html\">Observation Nottingham total score of primary malignant neoplasm of breast (observable entity)</a></li><li><a href=\"Observation-IntegratedAssociatedDCIS.html\">Observation DCIS intraduct ext Br ca spec Ql Micro</a></li><li><a href=\"Observation-IntegratedDCISGrade.html\">Observation Nuclear grade of ductal carcinoma in situ of breast (observable entity)</a></li><li><a href=\"Observation-IntegratedDCISArchitecture.html\">Observation Growth pattern of DCIS [Type] in Breast cancer specimen by Light microscopy</a></li><li><a href=\"Observation-IntegratedDCISNecrosis.html\">Observation DCIS necrosis [Type] in Breast cancer specimen by Light microscopy</a></li><li><a href=\"Observation-IntegratedTumorExtent.html\">Observation Adjacent structure invaded by tumor [Anatomy] in Breast cancer specimen by Light microscopy</a></li><li><a href=\"Observation-IntegratedMarginStatusInvasive.html\">Observation Margin involved BT</a></li><li><a href=\"Observation-IntegratedClosestMargin.html\">Observation IC uninv marg closest BT</a></li><li><a href=\"Observation-IntegratedMinDistanceInvasive.html\">Observation IC uninv marg dist closest BT</a></li><li><a href=\"Observation-IntegratedMarginStatusNonInvasive.html\">Observation Surgical margin DCIS involvement [Presence] in Breast cancer specimen by Light microscopy</a></li><li><a href=\"Observation-IntegratedMinDistanceNonInvasive.html\">Observation DCIS.uninv marg dist.closest BT</a></li><li><a href=\"Observation-IntegratedLVI.html\">Observation Lymph-vascular invasion Ca spec</a></li><li><a href=\"Observation-IntegratedMicrocalcification.html\">Observation Presence of microcalcification in excised breast specimen (observable entity)</a></li><li><a href=\"Observation-IntegratedERStatus.html\">Observation Estrogen receptor [Interpretation] in Tissue</a></li><li><a href=\"Observation-IntegratedERPercentage.html\">Observation Cells.estrogen receptor/cells in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-IntegratedERIntensity.html\">Observation Estrogen receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-IntegratedPRStatus.html\">Observation Progesterone receptor [Interpretation] in Tissue</a></li><li><a href=\"Observation-IntegratedPRPercentage.html\">Observation Cells.progesterone receptor/cells in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-IntegratedPRIntensity.html\">Observation Progesterone receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-IntegratedHER2IHC.html\">Observation HER2 [Presence] in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-IntegratedHER2ISH.html\">Observation ERBB2 gene duplication [Presence] in Breast cancer specimen by FISH</a></li><li><a href=\"Observation-IntegratedHER2Overall.html\">Observation HER2 [Interpretation] in Tissue</a></li><li><a href=\"Observation-IntegratedKi67.html\">Observation Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-IntegratedPT.html\">Observation pT category (observable entity)</a></li><li><a href=\"Observation-IntegratedBETComment.html\">Observation Pathology report comments [Interpretation] Narrative</a></li><li><a href=\"Observation-IntegratedLymphNodeProcedure.html\">Observation Surgery procedure for regional nodes at facility.YYY Cancer</a></li><li><a href=\"Observation-IntegratedLymphNodeLaterality.html\">Observation Anatomic part Laterality</a></li><li><a href=\"Observation-IntegratedNonSLNExamined.html\">Observation Regional lymph nodes examined [#] Specimen</a></li><li><a href=\"Observation-IntegratedNonSLNPositive.html\">Observation Regional lymph nodes positive [#] Specimen</a></li><li><a href=\"Observation-IntegratedSLNExamined.html\">Observation Sentinel lymph nodes examined [#] in Cancer specimen by Light microscopy</a></li><li><a href=\"Observation-IntegratedSLNPositive.html\">Observation Number of sentinel lymph nodes containing metastatic neoplasm in excised specimen (observable entity)</a></li><li><a href=\"Observation-IntegratedTotalExamined.html\">Observation Lymph nodes examined [#] in Cancer specimen by Light microscopy</a></li><li><a href=\"Observation-IntegratedTotalPositive.html\">Observation Lymph nodes with metastasis [#] in Cancer specimen</a></li><li><a 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      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedOperativeProcedure\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedOperativeProcedure</b></p><a name=\"IntegratedOperativeProcedure\"> </a><a name=\"hcIntegratedOperativeProcedure\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 29306-8}, {http://snomed.info/sct 2620001000004108}\">Operatives Verfahren</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 237371007}\">Brusterhaltende Therapie (BET)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "29306-8",
          "display" : "Surgery procedure"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "2620001000004108",
          "display" : "Specimen collection procedure (observable entity)"
        }],
        "text" : "Operatives Verfahren"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "237371007",
          "display" : "Wide local excision of breast lesion (procedure)"
        }],
        "text" : "Brusterhaltende Therapie (BET)"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMaterialType",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMaterialType",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMaterialType\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMaterialType</b></p><a name=\"IntegratedMaterialType\"> </a><a name=\"hcIntegratedMaterialType\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 66746-9}\">Materialart</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">Exzisionspräparat</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "66746-9",
          "display" : "Specimen type"
        }],
        "text" : "Materialart"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "Exzisionspräparat"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedLaterality",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedLaterality",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedLaterality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedLaterality</b></p><a name=\"IntegratedLaterality\"> </a><a name=\"hcIntegratedLaterality\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 384727002}\">Seitenlokalisation der Probe</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 7771000}\">Links</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "384727002",
          "display" : "Specimen laterality (observable entity)"
        }],
        "text" : "Seitenlokalisation der Probe"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "7771000",
          "display" : "Left (qualifier value)"
        }],
        "text" : "Links"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedAttachedTissue",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedAttachedTissue",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedAttachedTissue\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedAttachedTissue</b></p><a name=\"IntegratedAttachedTissue\"> </a><a name=\"hcIntegratedAttachedTissue\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85298-8}\">Material/anhängendes Gewebe</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 39937001}\">Haut</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85298-8",
          "display" : "Body structure included in specimen [Anatomy] in Specimen"
        }],
        "text" : "Material/anhängendes Gewebe"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "39937001",
          "display" : "Skin structure (body structure)"
        }],
        "text" : "Haut"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedFocality",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedFocality",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedFocality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedFocality</b></p><a name=\"IntegratedFocality\"> </a><a name=\"hcIntegratedFocality\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1157128007}\">(Multi)fokalität</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">Unifokal</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1157128007",
          "display" : "Qualitative distribution of primary malignant neoplasm of breast in excised breast specimen (observable entity)"
        }],
        "text" : "(Multi)fokalität"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "Unifokal"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMaxDiameterInvasive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMaxDiameterInvasive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMaxDiameterInvasive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMaxDiameterInvasive</b></p><a name=\"IntegratedMaxDiameterInvasive\"> </a><a name=\"hcIntegratedMaxDiameterInvasive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44635-1}, {http://snomed.info/sct 200001000004104}\">Maximaler Durchmesser invasives Karzinom</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 18 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44635-1",
          "display" : "Inv comp size max dim BT"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "200001000004104",
          "display" : "Greatest length dimension of excised primary malignant neoplasm (observable entity)"
        }],
        "text" : "Maximaler Durchmesser invasives Karzinom"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 18,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMaxOverallDiameter",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMaxOverallDiameter",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMaxOverallDiameter\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMaxOverallDiameter</b></p><a name=\"IntegratedMaxOverallDiameter\"> </a><a name=\"hcIntegratedMaxOverallDiameter\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 33728-7}\">Maximaler Gesamtdurchmesser der Läsion</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 22 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "33728-7",
          "display" : "Size.maximum dimension in Tumor"
        }],
        "text" : "Maximaler Gesamtdurchmesser der Läsion"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 22,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedHistologicalType",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedHistologicalType",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedHistologicalType\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedHistologicalType</b></p><a name=\"IntegratedHistologicalType\"> </a><a name=\"hcIntegratedHistologicalType\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44638-5}, {http://snomed.info/sct 1660001000004100}\">Histologischer Tumortyp WHO</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{urn:oid:2.16.840.1.113883.6.43.1 8500/3}\">Invasives duktales Karzinom (NST)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44638-5",
          "display" : "Histo type BT"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1660001000004100",
          "display" : "Histologic type of primary malignant neoplasm of breast (observable entity)"
        }],
        "text" : "Histologischer Tumortyp WHO"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "urn:oid:2.16.840.1.113883.6.43.1",
          "code" : "8500/3",
          "display" : "Invasives duktales Karzinom (NST)"
        }]
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMorphologyFreeText",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMorphologyFreeText",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMorphologyFreeText\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMorphologyFreeText</b></p><a name=\"IntegratedMorphologyFreeText\"> </a><a name=\"hcIntegratedMorphologyFreeText\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 33731-1}\">Morphologie Freitext</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.</p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "33731-1",
          "display" : "Histology type in Cancer specimen Narrative"
        }],
        "text" : "Morphologie Freitext"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueString" : "Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.",
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedNottinghamGrade",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedNottinghamGrade",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedNottinghamGrade\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedNottinghamGrade</b></p><a name=\"IntegratedNottinghamGrade\"> </a><a name=\"hcIntegratedNottinghamGrade\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44648-4}\">Histologischer Tumorgrad (Elston-Ellis-Grad)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 1155703007}\">Nottingham Grad 2 (Score 6)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44648-4",
          "display" : "Histologic grade [Score] in Breast cancer specimen by Nottingham"
        }],
        "text" : "Histologischer Tumorgrad (Elston-Ellis-Grad)"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1155703007",
          "display" : "G2: Moderately differentiated histologic grade (qualifier value)"
        }],
        "text" : "Nottingham Grad 2 (Score 6)"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedTubuleScore",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedTubuleScore",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedTubuleScore\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedTubuleScore</b></p><a name=\"IntegratedTubuleScore\"> </a><a name=\"hcIntegratedTubuleScore\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85321-8}\">Tubulus Scorewert</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 3 score<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85321-8",
          "display" : "Glandular differentiation [Score] in Breast cancer specimen by Nottingham"
        }],
        "text" : "Tubulus Scorewert"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 3,
        "unit" : "score",
        "system" : "http://unitsofmeasure.org",
        "code" : "{score}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedNuclearPleomorphism",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedNuclearPleomorphism",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedNuclearPleomorphism\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedNuclearPleomorphism</b></p><a name=\"IntegratedNuclearPleomorphism\"> </a><a name=\"hcIntegratedNuclearPleomorphism\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44645-0}\">Kernpleomorphie Scorewert</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 2 score<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44645-0",
          "display" : "Nuclear pleomorphism in Breast tumor by Nottingham"
        }],
        "text" : "Kernpleomorphie Scorewert"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 2,
        "unit" : "score",
        "system" : "http://unitsofmeasure.org",
        "code" : "{score}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMitosisCount",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMitosisCount",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMitosisCount\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMitosisCount</b></p><a name=\"IntegratedMitosisCount\"> </a><a name=\"hcIntegratedMitosisCount\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 406094009}\">Mitosezahl</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 4 per 10 HPF<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{HPF} = '{HPF}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "406094009",
          "display" : "Number of mitoses per 10 high power fields (observable entity)"
        }],
        "text" : "Mitosezahl"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 4,
        "unit" : "per 10 HPF",
        "system" : "http://unitsofmeasure.org",
        "code" : "{HPF}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMitoticRateScore",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMitoticRateScore",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMitoticRateScore\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMitoticRateScore</b></p><a name=\"IntegratedMitoticRateScore\"> </a><a name=\"hcIntegratedMitoticRateScore\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85300-2}\">Mitoserate Scorewert</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 score<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85300-2",
          "display" : "Mitotic rate [Score] in Breast cancer specimen by Nottingham"
        }],
        "text" : "Mitoserate Scorewert"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 1,
        "unit" : "score",
        "system" : "http://unitsofmeasure.org",
        "code" : "{score}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedElstonEllisScore",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedElstonEllisScore",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedElstonEllisScore\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedElstonEllisScore</b></p><a name=\"IntegratedElstonEllisScore\"> </a><a name=\"hcIntegratedElstonEllisScore\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1287461000}\">Elston-Ellis-Summenscore</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 6 score<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1287461000",
          "display" : "Nottingham total score of primary malignant neoplasm of breast (observable entity)"
        }],
        "text" : "Elston-Ellis-Summenscore"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 6,
        "unit" : "score",
        "system" : "http://unitsofmeasure.org",
        "code" : "{score}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedAssociatedDCIS",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedAssociatedDCIS",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedAssociatedDCIS\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedAssociatedDCIS</b></p><a name=\"IntegratedAssociatedDCIS\"> </a><a name=\"hcIntegratedAssociatedDCIS\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85336-6}\">Klassifikation eines assoziiertes DCIS</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 52101004}\">DCIS vorhanden</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85336-6",
          "display" : "DCIS intraduct ext Br ca spec Ql Micro"
        }],
        "text" : "Klassifikation eines assoziiertes DCIS"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "52101004",
          "display" : "Present (qualifier value)"
        }],
        "text" : "DCIS vorhanden"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedDCISGrade",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedDCISGrade",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedDCISGrade\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedDCISGrade</b></p><a name=\"IntegratedDCISGrade\"> </a><a name=\"hcIntegratedDCISGrade\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 2890001000004108}\">Kerngrading / WHO-Grading nichtinvasiv</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">Intermediär (Grad 2)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2890001000004108",
          "display" : "Nuclear grade of ductal carcinoma in situ of breast (observable entity)"
        }],
        "text" : "Kerngrading / WHO-Grading nichtinvasiv"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "Intermediär (Grad 2)"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedDCISArchitecture",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedDCISArchitecture",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedDCISArchitecture\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedDCISArchitecture</b></p><a name=\"IntegratedDCISArchitecture\"> </a><a name=\"hcIntegratedDCISArchitecture\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85302-8}, {http://snomed.info/sct 3400001000004108}\">DCIS Architektur</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 443987001}\">kribriformer Typ</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85302-8",
          "display" : "Growth pattern of DCIS [Type] in Breast cancer specimen by Light microscopy"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "3400001000004108",
          "display" : "Architectural pattern of ductal carcinoma in situ in breast (observable entity)"
        }],
        "text" : "DCIS Architektur"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "443987001",
          "display" : "Cribriform neoplasm pattern (finding)"
        }],
        "text" : "kribriformer Typ"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedDCISNecrosis",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedDCISNecrosis",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedDCISNecrosis\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedDCISNecrosis</b></p><a name=\"IntegratedDCISNecrosis\"> </a><a name=\"hcIntegratedDCISNecrosis\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85340-8}\">Nekrosen</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">Fokal (Komedo-Nekrosen)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85340-8",
          "display" : "DCIS necrosis [Type] in Breast cancer specimen by Light microscopy"
        }],
        "text" : "Nekrosen"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "Fokal (Komedo-Nekrosen)"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedTumorExtent",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedTumorExtent",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedTumorExtent\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedTumorExtent</b></p><a name=\"IntegratedTumorExtent\"> </a><a name=\"hcIntegratedTumorExtent\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85322-6}, {http://snomed.info/sct 396645007}, {http://snomed.info/sct 3280001000004106}\">Tumorausdehnung</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">Auf Brustdrüse beschränkt</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85322-6",
          "display" : "Adjacent structure invaded by tumor [Anatomy] in Breast cancer specimen by Light microscopy"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "396645007",
          "display" : "Status of extension by tumor (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "3280001000004106",
          "display" : "Anatomic location directly invaded by primary malignant neoplasm of breast (observable entity)"
        }],
        "text" : "Tumorausdehnung"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "Auf Brustdrüse beschränkt"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMarginStatusInvasive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMarginStatusInvasive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMarginStatusInvasive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMarginStatusInvasive</b></p><a name=\"IntegratedMarginStatusInvasive\"> </a><a name=\"hcIntegratedMarginStatusInvasive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44669-0}, {http://snomed.info/sct 371488000}, {http://snomed.info/sct 1240395000}\">Resektionsrandstatus invasiv</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 2667000}\">Nicht befallen (R0)</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideRR-Superior-HE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44669-0",
          "display" : "Margin involved BT"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "371488000",
          "display" : "Presence of neoplasm at excised surgical margin (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1240395000",
          "display" : "Surgical margin involved by primary malignant neoplasm of breast in excised breast specimen (observable entity)"
        }],
        "text" : "Resektionsrandstatus invasiv"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2667000",
          "display" : "Absent (qualifier value)"
        }],
        "text" : "Nicht befallen (R0)"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideRR-Superior-HE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedClosestMargin",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedClosestMargin",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedClosestMargin\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedClosestMargin</b></p><a name=\"IntegratedClosestMargin\"> </a><a name=\"hcIntegratedClosestMargin\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44674-0}, {http://snomed.info/sct 170001000004107}\">Richtung des nächsten tumorfreien RR</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">Posterior</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideRR-Superior-HE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44674-0",
          "display" : "IC uninv marg closest BT"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "170001000004107",
          "display" : "Surgical margin closest to malignant neoplasm in excised specimen of breast (observable entity)"
        }],
        "text" : "Richtung des nächsten tumorfreien RR"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "Posterior"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideRR-Superior-HE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMinDistanceInvasive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMinDistanceInvasive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMinDistanceInvasive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMinDistanceInvasive</b></p><a name=\"IntegratedMinDistanceInvasive\"> </a><a name=\"hcIntegratedMinDistanceInvasive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44672-4}, {http://snomed.info/sct 373120008}\">Mindestabstand des invasiven Tumor zum nächstgelegenen Resektionsrand</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 5 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideRR-Superior-HE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44672-4",
          "display" : "IC uninv marg dist closest BT"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "373120008",
          "display" : "Distance of invasive carcinoma of breast from closest surgical margin in excised breast specimen (observable entity)"
        }],
        "text" : "Mindestabstand des invasiven Tumor zum nächstgelegenen Resektionsrand"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 5,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideRR-Superior-HE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMarginStatusNonInvasive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMarginStatusNonInvasive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMarginStatusNonInvasive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMarginStatusNonInvasive</b></p><a name=\"IntegratedMarginStatusNonInvasive\"> </a><a name=\"hcIntegratedMarginStatusNonInvasive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85334-1}, {http://snomed.info/sct 384705006}\">Resektionsrandstatus nichtinvasiv</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 2667000}\">Nicht befallen</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideRR-Superior-HE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85334-1",
          "display" : "Surgical margin DCIS involvement [Presence] in Breast cancer specimen by Light microscopy"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "384705006",
          "display" : "Presence of ductal carcinoma in situ at surgical margin in excised specimen of breast (observable entity)"
        }],
        "text" : "Resektionsrandstatus nichtinvasiv"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2667000",
          "display" : "Absent (qualifier value)"
        }],
        "text" : "Nicht befallen"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideRR-Superior-HE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMinDistanceNonInvasive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMinDistanceNonInvasive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMinDistanceNonInvasive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMinDistanceNonInvasive</b></p><a name=\"IntegratedMinDistanceNonInvasive\"> </a><a name=\"hcIntegratedMinDistanceNonInvasive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 44673-2}\">Mindestabstand vom RR zum nichtinvasiven Tumor</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 3 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideRR-Superior-HE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "44673-2",
          "display" : "DCIS.uninv marg dist.closest BT"
        }],
        "text" : "Mindestabstand vom RR zum nichtinvasiven Tumor"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 3,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideRR-Superior-HE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedLVI",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedLVI",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedLVI\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedLVI</b></p><a name=\"IntegratedLVI\"> </a><a name=\"hcIntegratedLVI\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 59544-7}, {http://snomed.info/sct 371512006}\">Peritumorale Gefäßinvasion</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 2667000}\">Nicht nachgewiesen</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "59544-7",
          "display" : "Lymph-vascular invasion Ca spec"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "371512006",
          "display" : "Presence of direct invasion by primary malignant neoplasm to lymphatic vessel and/or small blood vessel (observable entity)"
        }],
        "text" : "Peritumorale Gefäßinvasion"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2667000",
          "display" : "Absent (qualifier value)"
        }],
        "text" : "Nicht nachgewiesen"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMicrocalcification",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMicrocalcification",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMicrocalcification\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMicrocalcification</b></p><a name=\"IntegratedMicrocalcification\"> </a><a name=\"hcIntegratedMicrocalcification\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1240404008}\">Presence of microcalcification in excised breast specimen (observable entity)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA27826-9}\">Microcalcifications present in DCIS</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1240404008",
          "display" : "Presence of microcalcification in excised breast specimen (observable entity)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "LA27826-9",
          "display" : "Microcalcifications present in DCIS"
        }]
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedERStatus",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedERStatus",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedERStatus\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedERStatus</b></p><a name=\"IntegratedERStatus\"> </a><a name=\"hcIntegratedERStatus\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 16112-5}, {http://snomed.info/sct 1234806008}\">Hormonrezeptorstatus Östrogen</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 52101004}\">Positiv</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideER01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3467}\">ESR1</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "16112-5",
          "display" : "Estrogen receptor [Interpretation] in Tissue"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "Hormonrezeptorstatus Östrogen"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "52101004",
          "display" : "Present (qualifier value)"
        }],
        "text" : "Positiv"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideER01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:3467",
            "display" : "ESR1"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedERPercentage",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedERPercentage",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedERPercentage\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedERPercentage</b></p><a name=\"IntegratedERPercentage\"> </a><a name=\"hcIntegratedERPercentage\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85329-1}, {http://snomed.info/sct 1234804006}, {http://snomed.info/sct 1234806008}\">PP ER</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 90 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideER01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3467}\">ESR1</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85329-1",
          "display" : "Cells.estrogen receptor/cells in Breast cancer specimen by Immune stain"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234804006",
          "display" : "Percent of cells with estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "PP ER"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 90,
        "unit" : "%",
        "system" : "http://unitsofmeasure.org",
        "code" : "%"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideER01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:3467",
            "display" : "ESR1"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedERIntensity",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedERIntensity",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedERIntensity\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedERIntensity</b></p><a name=\"IntegratedERIntensity\"> </a><a name=\"hcIntegratedERIntensity\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85310-1}, {http://snomed.info/sct 1236874005}, {http://snomed.info/sct 1234806008}\">Färbeintensität ER</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 24484000}\">Stark</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideER01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3467}\">ESR1</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85310-1",
          "display" : "Estrogen receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1236874005",
          "display" : "Intensity of stain of estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "Färbeintensität ER"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "24484000",
          "display" : "Severe (severity modifier) (qualifier value)"
        }],
        "text" : "Stark"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideER01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:3467",
            "display" : "ESR1"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedPRStatus",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedPRStatus",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedPRStatus\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedPRStatus</b></p><a name=\"IntegratedPRStatus\"> </a><a name=\"hcIntegratedPRStatus\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 16113-3}, {http://snomed.info/sct 1234806008}\">Hormonrezeptorstatus Progesteron</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 52101004}\">Positiv</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlidePR01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:8910}\">PGR</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "16113-3",
          "display" : "Progesterone receptor [Interpretation] in Tissue"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "Hormonrezeptorstatus Progesteron"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "52101004",
          "display" : "Present (qualifier value)"
        }],
        "text" : "Positiv"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlidePR01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:8910",
            "display" : "PGR"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedPRPercentage",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedPRPercentage",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedPRPercentage\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedPRPercentage</b></p><a name=\"IntegratedPRPercentage\"> </a><a name=\"hcIntegratedPRPercentage\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85325-9}, {http://snomed.info/sct 1234803000}, {http://snomed.info/sct 1234806008}\">PP PR</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 60 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlidePR01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:8910}\">PGR</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85325-9",
          "display" : "Cells.progesterone receptor/cells in Breast cancer specimen by Immune stain"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234803000",
          "display" : "Percent of cells with progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "PP PR"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 60,
        "unit" : "%",
        "system" : "http://unitsofmeasure.org",
        "code" : "%"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlidePR01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:8910",
            "display" : "PGR"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedPRIntensity",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedPRIntensity",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedPRIntensity\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedPRIntensity</b></p><a name=\"IntegratedPRIntensity\"> </a><a name=\"hcIntegratedPRIntensity\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85331-7}, {http://snomed.info/sct 1237278006}, {http://snomed.info/sct 1234806008}\">Färbeintensität PR</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 6736007}\">Mäßig</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlidePR01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:8910}\">PGR</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85331-7",
          "display" : "Progesterone receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1237278006",
          "display" : "Intensity of stain of progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "Färbeintensität PR"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "6736007",
          "display" : "Moderate (severity modifier) (qualifier value)"
        }],
        "text" : "Mäßig"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlidePR01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:8910",
            "display" : "PGR"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedHER2IHC",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedHER2IHC",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedHER2IHC\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedHER2IHC</b></p><a name=\"IntegratedHER2IHC\"> </a><a name=\"hcIntegratedHER2IHC\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85319-2}, {http://snomed.info/sct 3550001000004108}, {http://snomed.info/sct 1234806008}\">Her2 Score</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:\">1+</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHER2IHC01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3430}\">ERBB2</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85319-2",
          "display" : "HER2 [Presence] in Breast cancer specimen by Immune stain"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "3550001000004108",
          "display" : "Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "Her2 Score"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "text" : "1+"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHER2IHC01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:3430",
            "display" : "ERBB2"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedHER2ISH",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedHER2ISH",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedHER2ISH\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedHER2ISH</b></p><a name=\"IntegratedHER2ISH\"> </a><a name=\"hcIntegratedHER2ISH\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85318-4}\">Her2 Amplifikation</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 2667000}\">Nicht amplifiziert</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHER2IHC01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3430}\">ERBB2</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85318-4",
          "display" : "ERBB2 gene duplication [Presence] in Breast cancer specimen by FISH"
        }],
        "text" : "Her2 Amplifikation"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2667000",
          "display" : "Absent (qualifier value)"
        }],
        "text" : "Nicht amplifiziert"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHER2IHC01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:3430",
            "display" : "ERBB2"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedHER2Overall",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedHER2Overall",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedHER2Overall\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedHER2Overall</b></p><a name=\"IntegratedHER2Overall\"> </a><a name=\"hcIntegratedHER2Overall\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 48676-1}\">Her2neuStatus</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 2667000}\">Negativ</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideHER2IHC01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3430}\">ERBB2</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "48676-1",
          "display" : "HER2 [Interpretation] in Tissue"
        }],
        "text" : "Her2neuStatus"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2667000",
          "display" : "Absent (qualifier value)"
        }],
        "text" : "Negativ"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideHER2IHC01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:3430",
            "display" : "ERBB2"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedKi67",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedKi67",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedKi67\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedKi67</b></p><a name=\"IntegratedKi67\"> </a><a name=\"hcIntegratedKi67\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85330-9}, {http://snomed.info/sct 1237281001}, {http://snomed.info/sct 1234806008}\">Ki67-Index</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 15 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedBETSlideKi67-01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_Ki67_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:7107}\">MKI67</span></td></tr></table></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85330-9",
          "display" : "Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1237281001",
          "display" : "Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"
        },
        {
          "system" : "http://snomed.info/sct",
          "code" : "1234806008",
          "display" : "Observation using immunohistochemistry (observable entity)"
        }],
        "text" : "Ki67-Index"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 15,
        "unit" : "%",
        "system" : "http://unitsofmeasure.org",
        "code" : "%"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedBETSlideKi67-01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }],
      "component" : [{
        "code" : {
          "coding" : [{
            "system" : "http://loinc.org",
            "code" : "48018-6",
            "display" : "Gene studied [ID]"
          }]
        },
        "valueCodeableConcept" : {
          "coding" : [{
            "system" : "http://www.genenames.org/geneId",
            "code" : "HGNC:7107",
            "display" : "MKI67"
          }]
        }
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedPT",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedPT",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedPT\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedPT</b></p><a name=\"IntegratedPT\"> </a><a name=\"hcIntegratedPT\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie\">MII PR Onkologie TNM T-Kategorie</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 384625004}\">pT category (observable entity)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>value</b>: <span title=\"Codes:{https://www.uicc.org/resources/tnm T1}\">T1</span></p><p><b>method</b>: <span title=\"Codes:{https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version 8}\">8. Auflage</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix",
          "valueCodeableConcept" : {
            "coding" : [{
              "system" : "https://www.uicc.org/resources/tnm",
              "code" : "p",
              "display" : "p"
            }]
          }
        }],
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "384625004",
          "display" : "pT category (observable entity)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "https://www.uicc.org/resources/tnm",
          "code" : "T1",
          "display" : "T1"
        }]
      },
      "method" : {
        "coding" : [{
          "system" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version",
          "code" : "8",
          "display" : "8. Auflage"
        }]
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedBETComment",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedBETComment",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedBETComment\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedBETComment</b></p><a name=\"IntegratedBETComment\"> </a><a name=\"hcIntegratedBETComment\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 22638-1}\">Kommentar</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRBreastResection.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22638-1",
          "display" : "Pathology report comments [Interpretation] Narrative"
        }],
        "text" : "Kommentar"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueString" : "Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.",
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRBreastResection"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedLymphNodeProcedure",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedLymphNodeProcedure",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedLymphNodeProcedure\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedLymphNodeProcedure</b></p><a name=\"IntegratedLymphNodeProcedure\"> </a><a name=\"hcIntegratedLymphNodeProcedure\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 21877-6}\">LK OP Prozedur</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 396487001}\">Sentinel-Lymphknoten-Biopsie</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "21877-6",
          "display" : "Surgery procedure for regional nodes at facility.YYY Cancer"
        }],
        "text" : "LK OP Prozedur"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "396487001",
          "display" : "Sentinel lymph node biopsy (procedure)"
        }],
        "text" : "Sentinel-Lymphknoten-Biopsie"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedLymphNodeLaterality",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedLymphNodeLaterality",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedLymphNodeLaterality\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedLymphNodeLaterality</b></p><a name=\"IntegratedLymphNodeLaterality\"> </a><a name=\"hcIntegratedLymphNodeLaterality\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 20228-3}\">Seitenangabe</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 7771000}\">Links</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "20228-3",
          "display" : "Anatomic part Laterality"
        }],
        "text" : "Seitenangabe"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "7771000",
          "display" : "Left (qualifier value)"
        }],
        "text" : "Links"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedNonSLNExamined",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedNonSLNExamined",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedNonSLNExamined\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedNonSLNExamined</b></p><a name=\"IntegratedNonSLNExamined\"> </a><a name=\"hcIntegratedNonSLNExamined\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 21894-1}\">Anzahl untersuchter Non-SLN-axillärer LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "21894-1",
          "display" : "Regional lymph nodes examined [#] Specimen"
        }],
        "text" : "Anzahl untersuchter Non-SLN-axillärer LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 0,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedNonSLNPositive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedNonSLNPositive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedNonSLNPositive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedNonSLNPositive</b></p><a name=\"IntegratedNonSLNPositive\"> </a><a name=\"hcIntegratedNonSLNPositive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 21893-3}\">Anzahl befallener Non-SLN-axillärer LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "21893-3",
          "display" : "Regional lymph nodes positive [#] Specimen"
        }],
        "text" : "Anzahl befallener Non-SLN-axillärer LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 0,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedSLNExamined",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedSLNExamined",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedSLNExamined\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedSLNExamined</b></p><a name=\"IntegratedSLNExamined\"> </a><a name=\"hcIntegratedSLNExamined\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85347-3}\">Anzahl untersuchter Sentinel-LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 2 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85347-3",
          "display" : "Sentinel lymph nodes examined [#] in Cancer specimen by Light microscopy"
        }],
        "text" : "Anzahl untersuchter Sentinel-LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 2,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedSLNPositive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedSLNPositive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedSLNPositive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedSLNPositive</b></p><a name=\"IntegratedSLNPositive\"> </a><a name=\"hcIntegratedSLNPositive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1264491009}\">Anzahl befallener Sentinel-LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "1264491009",
          "display" : "Number of sentinel lymph nodes containing metastatic neoplasm in excised specimen (observable entity)"
        }],
        "text" : "Anzahl befallener Sentinel-LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 1,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedTotalExamined",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedTotalExamined",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedTotalExamined\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedTotalExamined</b></p><a name=\"IntegratedTotalExamined\"> </a><a name=\"hcIntegratedTotalExamined\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 92833-3}\">Gesamtzahl untersuchter Lymphknoten</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 2 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "92833-3",
          "display" : "Lymph nodes examined [#] in Cancer specimen by Light microscopy"
        }],
        "text" : "Gesamtzahl untersuchter Lymphknoten"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 2,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedTotalPositive",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedTotalPositive",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedTotalPositive\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedTotalPositive</b></p><a name=\"IntegratedTotalPositive\"> </a><a name=\"hcIntegratedTotalPositive\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 92831-7}\">Gesamtzahl befallener Lymphknoten</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "92831-7",
          "display" : "Lymph nodes with metastasis [#] in Cancer specimen"
        }],
        "text" : "Gesamtzahl befallener Lymphknoten"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 1,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMacroMetCount",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMacroMetCount",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMacroMetCount\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMacroMetCount</b></p><a name=\"IntegratedMacroMetCount\"> </a><a name=\"hcIntegratedMacroMetCount\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85343-2}\">Gesamtzahl makrometastatisch befallener LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85343-2",
          "display" : "Lymph nodes with macrometastases [#] in Cancer specimen by Light microscopy"
        }],
        "text" : "Gesamtzahl makrometastatisch befallener LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 0,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedMicroMetCount",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedMicroMetCount",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedMicroMetCount\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedMicroMetCount</b></p><a name=\"IntegratedMicroMetCount\"> </a><a name=\"hcIntegratedMicroMetCount\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85344-0}\">Gesamtzahl mikrometastatisch befallener LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85344-0",
          "display" : "Lymph nodes with micrometastases [#] in Cancer specimen by Light microscopy"
        }],
        "text" : "Gesamtzahl mikrometastatisch befallener LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 1,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedITCCount",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedITCCount",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedITCCount\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedITCCount</b></p><a name=\"IntegratedITCCount\"> </a><a name=\"hcIntegratedITCCount\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85352-3}\">Gesamtzahl ausschließlich ITC-befallener LK</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSpecimenPart.html\">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85352-3",
          "display" : "Lymph nodes with isolated tumor cells [#] in Cancer specimen by Light microscopy"
        }],
        "text" : "Gesamtzahl ausschließlich ITC-befallener LK"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 0,
        "unit" : "{count}",
        "system" : "http://unitsofmeasure.org",
        "code" : "{count}"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSpecimenPart"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedLargestMetSize",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedLargestMetSize",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedLargestMetSize\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedLargestMetSize</b></p><a name=\"IntegratedLargestMetSize\"> </a><a name=\"hcIntegratedLargestMetSize\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85351-5}\">Ausdehnung der größten metastatischen Infiltration</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1.2 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85351-5",
          "display" : "Lymph node metastatic deposit.max dimension [Length] in Cancer specimen by Light microscopy"
        }],
        "text" : "Ausdehnung der größten metastatischen Infiltration"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueQuantity" : {
        "value" : 1.2,
        "unit" : "mm",
        "system" : "http://unitsofmeasure.org",
        "code" : "mm"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedExtranodalExtension",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedExtranodalExtension",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedExtranodalExtension\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedExtranodalExtension</b></p><a name=\"IntegratedExtranodalExtension\"> </a><a name=\"hcIntegratedExtranodalExtension\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 85350-7}\">Extranodale Infiltration durch LK-Metastase</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://snomed.info/sct 2667000}\">Nicht vorhanden</span></p><p><b>specimen</b>: <a href=\"Specimen-IntegratedSLNSlideHE01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "85350-7",
          "display" : "Extranodal extension of carcinoma [Presence] in Cancer specimen by Light microscopy"
        }],
        "text" : "Extranodale Infiltration durch LK-Metastase"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "2667000",
          "display" : "Absent (qualifier value)"
        }],
        "text" : "Nicht vorhanden"
      },
      "specimen" : {
        "reference" : "Specimen/IntegratedSLNSlideHE01"
      },
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedPN",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedPN",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedPN\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedPN</b></p><a name=\"IntegratedPN\"> </a><a name=\"hcIntegratedPN\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie\">MII PR Onkologie TNM N-Kategorie</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 371494008}\">pN category (observable entity)</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>value</b>: <span title=\"Codes:{https://www.uicc.org/resources/tnm N1mi(sn)}\">N1mi(sn)</span></p><p><b>method</b>: <span title=\"Codes:{https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version 8}\">8. Auflage</span></p></div>"
      },
      "status" : "final",
      "code" : {
        "extension" : [{
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix",
          "valueCodeableConcept" : {
            "coding" : [{
              "system" : "https://www.uicc.org/resources/tnm",
              "code" : "p",
              "display" : "p"
            }]
          }
        }],
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "371494008",
          "display" : "pN category (observable entity)"
        }]
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "valueCodeableConcept" : {
        "coding" : [{
          "system" : "https://www.uicc.org/resources/tnm",
          "code" : "N1mi(sn)",
          "display" : "N1mi(sn)"
        }]
      },
      "method" : {
        "coding" : [{
          "system" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version",
          "code" : "8",
          "display" : "8. Auflage"
        }]
      }
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/Observation/IntegratedSLNComment",
    "resource" : {
      "resourceType" : "Observation",
      "id" : "IntegratedSLNComment",
      "meta" : {
        "profile" : ["https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"]
      },
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_IntegratedSLNComment\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Observation IntegratedSLNComment</b></p><a name=\"IntegratedSLNComment\"> </a><a name=\"hcIntegratedSLNComment\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-IntegratedReportRequest.html\">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 22638-1}\">Kommentar</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: In SLN #1 Nachweis einer Mikrometastase (1,2 mm) im Randsinus. SLN #2 tumorfrei in allen Schnittstufen. Keine extranodale Infiltration. Klassifikation: pN1mi(sn). Empfehlung: Besprechung in Tumorkonferenz bzgl. weiterer axillärer Therapie.</p><p><b>derivedFrom</b>: <a href=\"QuestionnaireResponse-IntegratedQRLymphNode.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>"
      },
      "basedOn" : [{
        "reference" : "ServiceRequest/IntegratedReportRequest"
      }],
      "status" : "final",
      "category" : [{
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }]
      },
      {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22637-3"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "http://loinc.org",
          "code" : "22638-1",
          "display" : "Pathology report comments [Interpretation] Narrative"
        }],
        "text" : "Kommentar"
      },
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "effectiveDateTime" : "2025-02-10",
      "performer" : [{
        "reference" : "Practitioner/PathologistPractitioner"
      }],
      "valueString" : "In SLN #1 Nachweis einer Mikrometastase (1,2 mm) im Randsinus. SLN #2 tumorfrei in allen Schnittstufen. Keine extranodale Infiltration. Klassifikation: pN1mi(sn). Empfehlung: Besprechung in Tumorkonferenz bzgl. weiterer axillärer Therapie.",
      "derivedFrom" : [{
        "reference" : "QuestionnaireResponse/IntegratedQRLymphNode"
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/QuestionnaireResponse/IntegratedQRBreastResection",
    "resource" : {
      "resourceType" : "QuestionnaireResponse",
      "id" : "IntegratedQRBreastResection",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"QuestionnaireResponse_IntegratedQRBreastResection\"> </a><p class=\"res-header-id\"><b>Generated Narrative: QuestionnaireResponse IntegratedQRBreastResection</b></p><a name=\"IntegratedQRBreastResection\"> </a><a name=\"hcIntegratedQRBreastResection\"> </a><table border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 2px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"The linkID for the item\">LinkID</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Text for the item\">Text</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Minimum and Maximum # of times the item can appear in the instance\">Definition</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"The type of the item\">Answer</a><span style=\"float: right\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_q_root.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"QuestionnaireResponseRoot\" class=\"hierarchy\"/> IntegratedQRBreastResection</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Questionnaire:http://breastcancerspec.org/Questionnaire/OP_Mamma_GH</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.root</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">BET Mamma</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.clinical</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Klinische Angaben</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11951</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Proben limitiert auswertbar</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/373067005\">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11912</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Präsentationsmodus</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Frisch</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11147</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Klinische Befunde / Anlass</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Z.n. Stanzbiopsie mit Nachweis eines invasiven Mammakarzinoms NST, G2</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11923</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Brustkrebsvorgeschichte</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ersterkrankung</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11952</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Vorchirurgische Therapie</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/373067005\">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11918</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Bildgebungsmodalität</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mammografie, Ultraschall</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11953</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Radiologische Ausdehnung</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>15 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10160</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Befundmarkierung</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Drahthäkchen</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10130</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Präparateradiographie</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ja, beigelegt</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11954</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genetische Prädisposition</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Nicht bekannt</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.macro</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Makroskopie</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10900</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Probengröße 1 (Länge)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>65 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10910</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Probengröße 2 (Breite)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>45 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10920</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Probengröße 3 (Tiefe)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>30 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10890</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gewicht</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>55 g<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10030</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Quadrant</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/33564002\">SNOMED CT: 33564002</a> (Structure of lower outer quadrant of breast (body structure))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10040</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Zifferblattlokalisation</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">5 Uhr</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10070</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Abstand Mamille</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>50 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.general</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Allgemeine Befunde</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11130</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Nichtinvasive Läsion</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/52101004\">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11270</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Invasives Karzinom</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/52101004\">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11919</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Operatives Verfahren</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/237371007\">SNOMED CT: 237371007</a> (Wide local excision of breast lesion (procedure))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10140</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Materialart</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Exzisionspräparat</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10800</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Seitenlokalisation</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/7771000\">SNOMED CT: 7771000</a> (Left (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11040</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Anhängendes Gewebe</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Haut</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11440</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Fokalität</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Unifokal</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.invasive</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Invasives Karzinom</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11400</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Max Durchmesser invasiv</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>18 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11420</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Max Gesamtdurchmesser</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>22 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11280</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Histologischer Tumortyp</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>unknown: 8500/3 (Invasives duktales Karzinom (NST))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11290</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Morphologie Freitext</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Invasives Mammakarzinom des NST, überwiegend trabekuläres und solides Wachstumsmuster</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11330</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Nottingham-Grad</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">G2</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11340</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Tubulus-Score</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">3</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11350</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Kernpleomorphie-Score</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">2</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11925</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mitosezahl</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">4/10 HPF</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11360</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mitoserate-Score</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11390</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Elston-Ellis-Summenscore</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">6</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11300</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Assoziiertes DCIS</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/52101004\">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 149</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">DCIS Kerngrading</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Intermediär (Grad 2)</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 150</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">DCIS Architektur</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Kribriform</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 151</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">DCIS Nekrosen</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Fokal (Komedo-Nekrosen)</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11926</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Tumorausdehnung</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Auf Brustdrüse beschränkt</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.margins</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Resektionsränder</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11470</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">RR-Status invasiv</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/2667000\">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11490</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Nächster tumorfreier RR</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Posterior</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11480</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mindestabstand invasiv</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>5 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11968</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">RR-Status nichtinvasiv</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/2667000\">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11970</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mindestabstand nichtinvasiv</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>3 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.additional</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Weitere Befunde</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11430</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">LVI</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/2667000\">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10880</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mikrokalzifikationen</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">In DCIS assoziiert</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.biomarkers</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Biomarker</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11750</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ER-Status</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/52101004\">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11720</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ER Prozent</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">90</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11730</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ER Färbeintensität</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Stark</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11790</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">PR-Status</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/52101004\">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11760</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">PR Prozent</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">60</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11770</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">PR Färbeintensität</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mäßig</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11810</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">HER2-Score (IHC)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1+</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11820</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">HER2-Amplifikation (ISH)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Nicht amplifiziert</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11830</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">HER2-Gesamtstatus</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Negativ</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11840</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ki-67-Index</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">15</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.tnm</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">TNM</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 169</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">pT-Kategorie</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">pT1c</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck001.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> bet.comment</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Kommentar</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11900</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Kommentar</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</td></tr>\r\n<tr><td colspan=\"4\" class=\"hierarchy\"><br/><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
      },
      "questionnaire" : "http://breastcancerspec.org/Questionnaire/OP_Mamma_GH",
      "status" : "completed",
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "authored" : "2025-02-10T14:30:00+01:00",
      "author" : {
        "reference" : "Practitioner/PathologistPractitioner"
      },
      "item" : [{
        "linkId" : "bet.root",
        "text" : "BET Mamma",
        "item" : [{
          "linkId" : "bet.clinical",
          "text" : "Klinische Angaben",
          "item" : [{
            "linkId" : "11951",
            "text" : "Proben limitiert auswertbar",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "373067005",
                "display" : "No (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11912",
            "text" : "Präsentationsmodus",
            "answer" : [{
              "valueString" : "Frisch"
            }]
          },
          {
            "linkId" : "11147",
            "text" : "Klinische Befunde / Anlass",
            "answer" : [{
              "valueString" : "Z.n. Stanzbiopsie mit Nachweis eines invasiven Mammakarzinoms NST, G2"
            }]
          },
          {
            "linkId" : "11923",
            "text" : "Brustkrebsvorgeschichte",
            "answer" : [{
              "valueString" : "Ersterkrankung"
            }]
          },
          {
            "linkId" : "11952",
            "text" : "Vorchirurgische Therapie",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "373067005",
                "display" : "No (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11918",
            "text" : "Bildgebungsmodalität",
            "answer" : [{
              "valueString" : "Mammografie, Ultraschall"
            }]
          },
          {
            "linkId" : "11953",
            "text" : "Radiologische Ausdehnung",
            "answer" : [{
              "valueQuantity" : {
                "value" : 15,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "10160",
            "text" : "Befundmarkierung",
            "answer" : [{
              "valueString" : "Drahthäkchen"
            }]
          },
          {
            "linkId" : "10130",
            "text" : "Präparateradiographie",
            "answer" : [{
              "valueString" : "Ja, beigelegt"
            }]
          },
          {
            "linkId" : "11954",
            "text" : "Genetische Prädisposition",
            "answer" : [{
              "valueString" : "Nicht bekannt"
            }]
          }]
        },
        {
          "linkId" : "bet.macro",
          "text" : "Makroskopie",
          "item" : [{
            "linkId" : "10900",
            "text" : "Probengröße 1 (Länge)",
            "answer" : [{
              "valueQuantity" : {
                "value" : 65,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "10910",
            "text" : "Probengröße 2 (Breite)",
            "answer" : [{
              "valueQuantity" : {
                "value" : 45,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "10920",
            "text" : "Probengröße 3 (Tiefe)",
            "answer" : [{
              "valueQuantity" : {
                "value" : 30,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "10890",
            "text" : "Gewicht",
            "answer" : [{
              "valueQuantity" : {
                "value" : 55,
                "unit" : "g",
                "system" : "http://unitsofmeasure.org",
                "code" : "g"
              }
            }]
          },
          {
            "linkId" : "10030",
            "text" : "Quadrant",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "33564002",
                "display" : "Structure of lower outer quadrant of breast (body structure)"
              }
            }]
          },
          {
            "linkId" : "10040",
            "text" : "Zifferblattlokalisation",
            "answer" : [{
              "valueString" : "5 Uhr"
            }]
          },
          {
            "linkId" : "10070",
            "text" : "Abstand Mamille",
            "answer" : [{
              "valueQuantity" : {
                "value" : 50,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          }]
        },
        {
          "linkId" : "bet.general",
          "text" : "Allgemeine Befunde",
          "item" : [{
            "linkId" : "11130",
            "text" : "Nichtinvasive Läsion",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "52101004",
                "display" : "Present (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11270",
            "text" : "Invasives Karzinom",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "52101004",
                "display" : "Present (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11919",
            "text" : "Operatives Verfahren",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "237371007",
                "display" : "Wide local excision of breast lesion (procedure)"
              }
            }]
          },
          {
            "linkId" : "10140",
            "text" : "Materialart",
            "answer" : [{
              "valueString" : "Exzisionspräparat"
            }]
          },
          {
            "linkId" : "10800",
            "text" : "Seitenlokalisation",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "7771000",
                "display" : "Left (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11040",
            "text" : "Anhängendes Gewebe",
            "answer" : [{
              "valueString" : "Haut"
            }]
          },
          {
            "linkId" : "11440",
            "text" : "Fokalität",
            "answer" : [{
              "valueString" : "Unifokal"
            }]
          }]
        },
        {
          "linkId" : "bet.invasive",
          "text" : "Invasives Karzinom",
          "item" : [{
            "linkId" : "11400",
            "text" : "Max Durchmesser invasiv",
            "answer" : [{
              "valueQuantity" : {
                "value" : 18,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "11420",
            "text" : "Max Gesamtdurchmesser",
            "answer" : [{
              "valueQuantity" : {
                "value" : 22,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "11280",
            "text" : "Histologischer Tumortyp",
            "answer" : [{
              "valueCoding" : {
                "system" : "urn:oid:2.16.840.1.113883.6.43.1",
                "code" : "8500/3",
                "display" : "Invasives duktales Karzinom (NST)"
              }
            }]
          },
          {
            "linkId" : "11290",
            "text" : "Morphologie Freitext",
            "answer" : [{
              "valueString" : "Invasives Mammakarzinom des NST, überwiegend trabekuläres und solides Wachstumsmuster"
            }]
          },
          {
            "linkId" : "11330",
            "text" : "Nottingham-Grad",
            "answer" : [{
              "valueString" : "G2"
            }]
          },
          {
            "linkId" : "11340",
            "text" : "Tubulus-Score",
            "answer" : [{
              "valueInteger" : 3
            }]
          },
          {
            "linkId" : "11350",
            "text" : "Kernpleomorphie-Score",
            "answer" : [{
              "valueInteger" : 2
            }]
          },
          {
            "linkId" : "11925",
            "text" : "Mitosezahl",
            "answer" : [{
              "valueString" : "4/10 HPF"
            }]
          },
          {
            "linkId" : "11360",
            "text" : "Mitoserate-Score",
            "answer" : [{
              "valueInteger" : 1
            }]
          },
          {
            "linkId" : "11390",
            "text" : "Elston-Ellis-Summenscore",
            "answer" : [{
              "valueInteger" : 6
            }]
          },
          {
            "linkId" : "11300",
            "text" : "Assoziiertes DCIS",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "52101004",
                "display" : "Present (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "149",
            "text" : "DCIS Kerngrading",
            "answer" : [{
              "valueString" : "Intermediär (Grad 2)"
            }]
          },
          {
            "linkId" : "150",
            "text" : "DCIS Architektur",
            "answer" : [{
              "valueString" : "Kribriform"
            }]
          },
          {
            "linkId" : "151",
            "text" : "DCIS Nekrosen",
            "answer" : [{
              "valueString" : "Fokal (Komedo-Nekrosen)"
            }]
          },
          {
            "linkId" : "11926",
            "text" : "Tumorausdehnung",
            "answer" : [{
              "valueString" : "Auf Brustdrüse beschränkt"
            }]
          }]
        },
        {
          "linkId" : "bet.margins",
          "text" : "Resektionsränder",
          "item" : [{
            "linkId" : "11470",
            "text" : "RR-Status invasiv",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "2667000",
                "display" : "Absent (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11490",
            "text" : "Nächster tumorfreier RR",
            "answer" : [{
              "valueString" : "Posterior"
            }]
          },
          {
            "linkId" : "11480",
            "text" : "Mindestabstand invasiv",
            "answer" : [{
              "valueQuantity" : {
                "value" : 5,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "11968",
            "text" : "RR-Status nichtinvasiv",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "2667000",
                "display" : "Absent (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11970",
            "text" : "Mindestabstand nichtinvasiv",
            "answer" : [{
              "valueQuantity" : {
                "value" : 3,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          }]
        },
        {
          "linkId" : "bet.additional",
          "text" : "Weitere Befunde",
          "item" : [{
            "linkId" : "11430",
            "text" : "LVI",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "2667000",
                "display" : "Absent (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "10880",
            "text" : "Mikrokalzifikationen",
            "answer" : [{
              "valueString" : "In DCIS assoziiert"
            }]
          }]
        },
        {
          "linkId" : "bet.biomarkers",
          "text" : "Biomarker",
          "item" : [{
            "linkId" : "11750",
            "text" : "ER-Status",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "52101004",
                "display" : "Present (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11720",
            "text" : "ER Prozent",
            "answer" : [{
              "valueInteger" : 90
            }]
          },
          {
            "linkId" : "11730",
            "text" : "ER Färbeintensität",
            "answer" : [{
              "valueString" : "Stark"
            }]
          },
          {
            "linkId" : "11790",
            "text" : "PR-Status",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "52101004",
                "display" : "Present (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11760",
            "text" : "PR Prozent",
            "answer" : [{
              "valueInteger" : 60
            }]
          },
          {
            "linkId" : "11770",
            "text" : "PR Färbeintensität",
            "answer" : [{
              "valueString" : "Mäßig"
            }]
          },
          {
            "linkId" : "11810",
            "text" : "HER2-Score (IHC)",
            "answer" : [{
              "valueString" : "1+"
            }]
          },
          {
            "linkId" : "11820",
            "text" : "HER2-Amplifikation (ISH)",
            "answer" : [{
              "valueString" : "Nicht amplifiziert"
            }]
          },
          {
            "linkId" : "11830",
            "text" : "HER2-Gesamtstatus",
            "answer" : [{
              "valueString" : "Negativ"
            }]
          },
          {
            "linkId" : "11840",
            "text" : "Ki-67-Index",
            "answer" : [{
              "valueInteger" : 15
            }]
          }]
        },
        {
          "linkId" : "bet.tnm",
          "text" : "TNM",
          "item" : [{
            "linkId" : "169",
            "text" : "pT-Kategorie",
            "answer" : [{
              "valueString" : "pT1c"
            }]
          }]
        },
        {
          "linkId" : "bet.comment",
          "text" : "Kommentar",
          "item" : [{
            "linkId" : "11900",
            "text" : "Kommentar",
            "answer" : [{
              "valueString" : "Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung."
            }]
          }]
        }]
      }]
    }
  },
  {
    "fullUrl" : "http://breastcancerspec.org/QuestionnaireResponse/IntegratedQRLymphNode",
    "resource" : {
      "resourceType" : "QuestionnaireResponse",
      "id" : "IntegratedQRLymphNode",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"QuestionnaireResponse_IntegratedQRLymphNode\"> </a><p class=\"res-header-id\"><b>Generated Narrative: QuestionnaireResponse IntegratedQRLymphNode</b></p><a name=\"IntegratedQRLymphNode\"> </a><a name=\"hcIntegratedQRLymphNode\"> </a><table border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 2px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"The linkID for the item\">LinkID</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Text for the item\">Text</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Minimum and Maximum # of times the item can appear in the instance\">Definition</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"The type of the item\">Answer</a><span style=\"float: right\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_q_root.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"QuestionnaireResponseRoot\" class=\"hierarchy\"/> IntegratedQRLymphNode</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Questionnaire:http://breastcancerspec.org/Questionnaire/OP_LN-Mamma</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> sln.root</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">SLN-Biopsie Axilla</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> sln.clinical</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Klinische Angaben</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11951</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Proben limitiert auswertbar</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/373067005\">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11950</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">LK-Biopsie veranlassende klinische/bildgebende Befunde</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Invasives Mammakarzinom NST links, cN0</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11148</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Bildgebende Befunde</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Mammografie, Sonographie: Axilla klinisch unauffällig</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 10210</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Neoadjuvante Therapie</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/373067005\">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> sln.macro</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Makroskopie</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> sln.macro.sln1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">SLN #1 Größe</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">12 x 8 x 6 mm, Patentblau-markiert</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> sln.macro.sln2</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">SLN #2 Größe</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">10 x 7 x 5 mm, Patentblau-markiert</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> sln.findings</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Axilläre Lymphknotenpräparate</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11540</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">LK OP Prozedur</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/396487001\">SNOMED CT: 396487001</a> (Sentinel lymph node biopsy (procedure))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11620</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Seitenangabe</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/7771000\">SNOMED CT: 7771000</a> (Left (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11630</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Anzahl der untersuchten (nonSLN)-axillären LK</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11640</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Anzahl der befallenen (nonSLN)-axillären LK</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11650</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Anzahl der untersuchten Sentinel-LK</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">2</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11660</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Anzahl der befallenen Sentinel-LK</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11944</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gesamtzahl untersuchter Lymphknoten</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">2</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11945</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gesamtzahl befallener Lymphknoten</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11947</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gesamtzahl makrometastatisch befallener Lymphknoten</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11948</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gesamtzahl mikrometastatisch befallener Lymphknoten</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11946</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Gesamtzahl ausschließlich ITC-befallener Lymphknoten</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0</td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11690</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Ausdehnung der größten metastatischen Infiltration</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span>1.2 mm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 11700</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Extranodale Infiltration durch LK-Metastase</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span><span><a href=\"http://snomed.info/id/2667000\">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck001.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Group\" class=\"hierarchy\"/> sln.tnm</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Pathologisches TNM-Staging</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-string.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Item\" class=\"hierarchy\"/> 175</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Regionäre Lymphknoten (pN-Kategorie)</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">pN1mi(sn)</td></tr>\r\n<tr><td colspan=\"4\" class=\"hierarchy\"><br/><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
      },
      "questionnaire" : "http://breastcancerspec.org/Questionnaire/OP_LN-Mamma",
      "status" : "completed",
      "subject" : {
        "reference" : "Patient/Patient4"
      },
      "authored" : "2025-02-10T14:30:00+01:00",
      "author" : {
        "reference" : "Practitioner/PathologistPractitioner"
      },
      "item" : [{
        "linkId" : "sln.root",
        "text" : "SLN-Biopsie Axilla",
        "item" : [{
          "linkId" : "sln.clinical",
          "text" : "Klinische Angaben",
          "item" : [{
            "linkId" : "11951",
            "text" : "Proben limitiert auswertbar",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "373067005",
                "display" : "No (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11950",
            "text" : "LK-Biopsie veranlassende klinische/bildgebende Befunde",
            "answer" : [{
              "valueString" : "Invasives Mammakarzinom NST links, cN0"
            }]
          },
          {
            "linkId" : "11148",
            "text" : "Bildgebende Befunde",
            "answer" : [{
              "valueString" : "Mammografie, Sonographie: Axilla klinisch unauffällig"
            }]
          },
          {
            "linkId" : "10210",
            "text" : "Neoadjuvante Therapie",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "373067005",
                "display" : "No (qualifier value)"
              }
            }]
          }]
        },
        {
          "linkId" : "sln.macro",
          "text" : "Makroskopie",
          "item" : [{
            "linkId" : "sln.macro.sln1",
            "text" : "SLN #1 Größe",
            "answer" : [{
              "valueString" : "12 x 8 x 6 mm, Patentblau-markiert"
            }]
          },
          {
            "linkId" : "sln.macro.sln2",
            "text" : "SLN #2 Größe",
            "answer" : [{
              "valueString" : "10 x 7 x 5 mm, Patentblau-markiert"
            }]
          }]
        },
        {
          "linkId" : "sln.findings",
          "text" : "Axilläre Lymphknotenpräparate",
          "item" : [{
            "linkId" : "11540",
            "text" : "LK OP Prozedur",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "396487001",
                "display" : "Sentinel lymph node biopsy (procedure)"
              }
            }]
          },
          {
            "linkId" : "11620",
            "text" : "Seitenangabe",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "7771000",
                "display" : "Left (qualifier value)"
              }
            }]
          },
          {
            "linkId" : "11630",
            "text" : "Anzahl der untersuchten (nonSLN)-axillären LK",
            "answer" : [{
              "valueInteger" : 0
            }]
          },
          {
            "linkId" : "11640",
            "text" : "Anzahl der befallenen (nonSLN)-axillären LK",
            "answer" : [{
              "valueInteger" : 0
            }]
          },
          {
            "linkId" : "11650",
            "text" : "Anzahl der untersuchten Sentinel-LK",
            "answer" : [{
              "valueInteger" : 2
            }]
          },
          {
            "linkId" : "11660",
            "text" : "Anzahl der befallenen Sentinel-LK",
            "answer" : [{
              "valueInteger" : 1
            }]
          },
          {
            "linkId" : "11944",
            "text" : "Gesamtzahl untersuchter Lymphknoten",
            "answer" : [{
              "valueInteger" : 2
            }]
          },
          {
            "linkId" : "11945",
            "text" : "Gesamtzahl befallener Lymphknoten",
            "answer" : [{
              "valueInteger" : 1
            }]
          },
          {
            "linkId" : "11947",
            "text" : "Gesamtzahl makrometastatisch befallener Lymphknoten",
            "answer" : [{
              "valueInteger" : 0
            }]
          },
          {
            "linkId" : "11948",
            "text" : "Gesamtzahl mikrometastatisch befallener Lymphknoten",
            "answer" : [{
              "valueInteger" : 1
            }]
          },
          {
            "linkId" : "11946",
            "text" : "Gesamtzahl ausschließlich ITC-befallener Lymphknoten",
            "answer" : [{
              "valueInteger" : 0
            }]
          },
          {
            "linkId" : "11690",
            "text" : "Ausdehnung der größten metastatischen Infiltration",
            "answer" : [{
              "valueQuantity" : {
                "value" : 1.2,
                "unit" : "mm",
                "system" : "http://unitsofmeasure.org",
                "code" : "mm"
              }
            }]
          },
          {
            "linkId" : "11700",
            "text" : "Extranodale Infiltration durch LK-Metastase",
            "answer" : [{
              "valueCoding" : {
                "system" : "http://snomed.info/sct",
                "code" : "2667000",
                "display" : "Absent (qualifier value)"
              }
            }]
          }]
        },
        {
          "linkId" : "sln.tnm",
          "text" : "Pathologisches TNM-Staging",
          "item" : [{
            "linkId" : "175",
            "text" : "Regionäre Lymphknoten (pN-Kategorie)",
            "answer" : [{
              "valueString" : "pN1mi(sn)"
            }]
          }]
        }]
      }]
    }
  }]
}