{
  "resourceType" : "Observation",
  "id" : "Fall7-PDL1-Status",
  "meta" : {
    "profile" : ["https://www.senologie.org/fhir/StructureDefinition/senologie-pdl1-status"]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation Fall7-PDL1-Status</b></p><a name=\"Fall7-PDL1-Status\"> </a><a name=\"hcFall7-PDL1-Status\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-senologie-pdl1-status.html\">BIH Senologie PD-L1 Status</a></p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs biomarker-category}\">A characterization of a given biomarker observation.</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1234806008}\">PD-L1 Immunhistochemie</span></p><p><b>subject</b>: <a href=\"Patient-Fall7-Patient-Kathrin-Mueller.html\">Kathrin Mueller  Female, DoB: 1977-06-17 ( http://fhir.bih-charite.de/sid/patient-id#SENO-2025-007)</a></p><p><b>effective</b>: 2025-04-10</p><p><b>method</b>: <span title=\"Codes:\">PD-L1 IHC 22C3 pharmDx (Dako/Agilent)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html C176582}\">PD-L1 Combined Positive Score</span></p><p><b>value</b>: 2 score<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>interpretation</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation NEG}\">Negative</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html C184941}\">PD-L1 Tumor Proportion Score</span></p><p><b>value</b>: 1 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></div>"
  },
  "status" : "final",
  "category" : [{
    "coding" : [{
      "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
      "code" : "laboratory"
    }]
  },
  {
    "coding" : [{
      "system" : "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
      "code" : "biomarker-category"
    }]
  }],
  "code" : {
    "coding" : [{
      "system" : "http://snomed.info/sct",
      "code" : "1234806008",
      "display" : "Observation using immunohistochemistry (observable entity)"
    }],
    "text" : "PD-L1 Immunhistochemie"
  },
  "subject" : {
    "reference" : "Patient/Fall7-Patient-Kathrin-Mueller"
  },
  "effectiveDateTime" : "2025-04-10",
  "method" : {
    "text" : "PD-L1 IHC 22C3 pharmDx (Dako/Agilent)"
  },
  "component" : [{
    "code" : {
      "coding" : [{
        "system" : "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
        "code" : "C176582",
        "display" : "PD-L1 Combined Positive Score"
      }]
    },
    "valueQuantity" : {
      "value" : 2,
      "unit" : "score",
      "system" : "http://unitsofmeasure.org",
      "code" : "{score}"
    },
    "interpretation" : [{
      "coding" : [{
        "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "code" : "NEG",
        "display" : "Negative"
      }]
    }]
  },
  {
    "code" : {
      "coding" : [{
        "system" : "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
        "code" : "C184941",
        "display" : "PD-L1 Tumor Proportion Score"
      }]
    },
    "valueQuantity" : {
      "value" : 1,
      "unit" : "%",
      "system" : "http://unitsofmeasure.org",
      "code" : "%"
    }
  }]
}