Breast Cancer Specification
0.1.0 - ci-build

Breast Cancer Specification - Local Development build (v0.1.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

: HER2 Gesamtstatus - Stanzbiopsie - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <https://loinc.org/rdf/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Observation ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "CoreNeedleBiopsyHER2Overall"] ; # 
  fhir:meta [
    ( fhir:profile [
fhir:v "https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"^^xsd:anyURI ;
fhir:l <https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding?version=2026.0.0>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation CoreNeedleBiopsyHER2Overall</b></p><a name=\"CoreNeedleBiopsyHER2Overall\"> </a><a name=\"hcCoreNeedleBiopsyHER2Overall\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding\">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href=\"ServiceRequest-CoreNeedleBiopsyReportRequest.html\">ServiceRequest Breast Pathology biopsy report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://loinc.org 22637-3}\">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 48676-1}\">Her2neuStatus</span></p><p><b>subject</b>: <a href=\"Patient-Patient4.html\">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-01-17</p><p><b>performer</b>: <a href=\"Practitioner-PathologistPractitioner.html\">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA6577-6}\">Negativ</span></p><p><b>specimen</b>: <a href=\"Specimen-CoreNeedleBiopsySpecimenSlideHER2-01.html\">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_105_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_105; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: </p><ul><li><a href=\"QuestionnaireResponse-QuestionnaireResponseCoreNeedleBiopsy.html\">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/Core-Needle-Biopsy' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href=\"Observation-CoreNeedleBiopsyHER2IHC.html\">Observation HER2 [Presence] in Breast cancer specimen by Immune stain</a></li><li><a href=\"Observation-CoreNeedleBiopsyHER2ISH.html\">Observation Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by in situ hybridization</a></li></ul><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></td><td><span title=\"Codes:{http://www.genenames.org/geneId HGNC:3430}\">ERBB2</span></td></tr></table></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:basedOn ( [
fhir:l fhir:ServiceRequest/CoreNeedleBiopsyReportRequest ;
fhir:reference [ fhir:v "ServiceRequest/CoreNeedleBiopsyReportRequest" ]
  ] ) ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:category ( [
    ( fhir:coding [
fhir:system [
fhir:v "http://terminology.hl7.org/CodeSystem/observation-category"^^xsd:anyURI ;
fhir:l <http://terminology.hl7.org/CodeSystem/observation-category>       ] ;
fhir:code [ fhir:v "laboratory" ]     ] )
  ] [
    ( fhir:coding [
a loinc:22637-3 ;
fhir:system [
fhir:v "http://loinc.org"^^xsd:anyURI ;
fhir:l <http://loinc.org>       ] ;
fhir:code [ fhir:v "22637-3" ]     ] )
  ] ) ; # 
  fhir:code [
    ( fhir:coding [
a loinc:48676-1 ;
fhir:system [
fhir:v "http://loinc.org"^^xsd:anyURI ;
fhir:l <http://loinc.org>       ] ;
fhir:code [ fhir:v "48676-1" ] ;
fhir:display [ fhir:v "HER2 [Interpretation] in Tissue" ]     ] ) ;
fhir:text [ fhir:v "Her2neuStatus" ]
  ] ; # 
  fhir:subject [
fhir:l fhir:Patient/Patient4 ;
fhir:reference [ fhir:v "Patient/Patient4" ]
  ] ; # 
  fhir:effective [
a fhir:DateTime ;
fhir:v "2025-01-17"^^xsd:date
  ] ; # 
  fhir:performer ( [
fhir:l fhir:Practitioner/PathologistPractitioner ;
fhir:reference [ fhir:v "Practitioner/PathologistPractitioner" ]
  ] ) ; # 
  fhir:value [
a fhir:CodeableConcept ;
    ( fhir:coding [
a loinc:LA6577-6 ;
fhir:system [
fhir:v "http://loinc.org"^^xsd:anyURI ;
fhir:l <http://loinc.org>       ] ;
fhir:code [ fhir:v "LA6577-6" ] ;
fhir:display [ fhir:v "Negative" ]     ] ) ;
fhir:text [ fhir:v "Negativ" ]
  ] ; # 
  fhir:specimen [
fhir:l fhir:Specimen/CoreNeedleBiopsySpecimenSlideHER2-01 ;
fhir:reference [ fhir:v "Specimen/CoreNeedleBiopsySpecimenSlideHER2-01" ]
  ] ; # 
  fhir:derivedFrom ( [
fhir:l fhir:QuestionnaireResponse/QuestionnaireResponseCoreNeedleBiopsy ;
fhir:reference [ fhir:v "QuestionnaireResponse/QuestionnaireResponseCoreNeedleBiopsy" ]
  ] [
fhir:l fhir:Observation/CoreNeedleBiopsyHER2IHC ;
fhir:reference [ fhir:v "Observation/CoreNeedleBiopsyHER2IHC" ]
  ] [
fhir:l fhir:Observation/CoreNeedleBiopsyHER2ISH ;
fhir:reference [ fhir:v "Observation/CoreNeedleBiopsyHER2ISH" ]
  ] ) ; # 
  fhir:component ( [
fhir:code [
      ( fhir:coding [
a loinc:48018-6 ;
fhir:system [
fhir:v "http://loinc.org"^^xsd:anyURI ;
fhir:l <http://loinc.org>         ] ;
fhir:code [ fhir:v "48018-6" ] ;
fhir:display [ fhir:v "Gene studied [ID]" ]       ] )     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [
fhir:v "http://www.genenames.org/geneId"^^xsd:anyURI ;
fhir:l <http://www.genenames.org/geneId>         ] ;
fhir:code [ fhir:v "HGNC:3430" ] ;
fhir:display [ fhir:v "ERBB2" ]       ] )     ]
  ] ) . #