Breast Cancer Specification - Local Development build (v0.1.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

Breast Resection — Specimens

The breast-conserving excision specimen comprises 22 specimen instances in a three-level hierarchy: part → paraffin blocks → slides, plus 7 substance instances for IHC reagents.

Part

Instance	Description
BreastResectionSpecimenPart	BCS excision specimen, left breast, with skin and wire localisation, 42×35×18 mm, 10 g

Paraffin Blocks

Instance	Description
BreastResectionSpecimenBlock01	Central tumour area, slice III (incl. anterior/posterior margins)
BreastResectionSpecimenBlock02	Central tumour area, slice V (incl. anterior/posterior margins)
BreastResectionSpecimenBlock03	Resection margin superior
BreastResectionSpecimenBlock04	Resection margin inferior
BreastResectionSpecimenBlock05	Resection margin medial (slice I)
BreastResectionSpecimenBlock06	Resection margin lateral (slice VIII)

Slides

H&E Stains — Block 01 (Tumour, Slice III)

Instance	Description
BreastResectionSpecimenSlideHE01	H&E slide, tumour area, section level 1
BreastResectionSpecimenSlideHE02	H&E slide, tumour area, section level 2

H&E Stains — Block 02 (Tumour, Slice V)

Instance	Description
BreastResectionSpecimenSlideBlock02-HE01	H&E slide, tumour area slice V, section level 1
BreastResectionSpecimenSlideBlock02-HE02	H&E slide, tumour area slice V, section level 2

H&E Stains — Resection Margins (Blocks 03–06)

Instance	Description
BreastResectionSpecimenSlideRR-Superior-HE01	H&E slide, resection margin superior
BreastResectionSpecimenSlideRR-Inferior-HE01	H&E slide, resection margin inferior
BreastResectionSpecimenSlideRR-Medial-HE01	H&E slide, resection margin medial
BreastResectionSpecimenSlideRR-Lateral-HE01	H&E slide, resection margin lateral

Immunohistochemistry (Block 01)

Instance	Stain	Description
BreastResectionSpecimenSlideER01	ER IHC	Oestrogen receptor immunohistochemistry
BreastResectionSpecimenSlidePR01	PR IHC	Progesterone receptor immunohistochemistry
BreastResectionSpecimenSlideHER2IHC01	HER2 IHC	HER2 immunohistochemistry
BreastResectionSpecimenSlideKi67-01	Ki-67 IHC	Ki-67 immunohistochemistry
BreastResectionSpecimenSlideCK18-01	CK18 IHC	Cytokeratin 18 immunohistochemistry
BreastResectionSpecimenSlidep40-01	p40 IHC	p40 immunohistochemistry
BreastResectionSpecimenSlideECad-01	E-Cadherin IHC	E-Cadherin immunohistochemistry