Breast Cancer Specification - Local Development build (v0.1.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

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: Document Bundle - Integrierter Bericht (BET + SLN) - XML Representation

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<Bundle xmlns="http://hl7.org/fhir">
  <id value="IntegratedDocument"/>
  <identifier>
    <system
            value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
    <value value="E_25_004"/>
  </identifier>
  <type value="document"/>
  <timestamp value="2025-02-10T17:00:00+01:00"/>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Composition/IntegratedComposition"/>
    <resource>
      <Composition>
        <id value="IntegratedComposition"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Composition_IntegratedComposition"> </a><p class="res-header-id"><b>Generated Narrative: Composition IntegratedComposition</b></p><a name="IntegratedComposition"> </a><a name="hcIntegratedComposition"> </a><p><b>identifier</b>: Accession ID/PATH-COMP-2025-300</p><p><b>status</b>: Final</p><p><b>type</b>: <span title="Codes:{http://ihe-d.de/CodeSystems/IHEXDStypeCode PATH}, {http://snomed.info/sct 371528001}">Pathology report (record artifact)</span></p><p><b>encounter</b>: <a href="Encounter-IntegratedEncounter.html">Encounter: identifier = http://example.hospital.de/encounters#E_25_300; status = finished; class = IMP (IMP)</a></p><p><b>date</b>: 2025-02-10 17:00:00+0100</p><p><b>author</b>: <a href="Organization-PathologyLabOrganization.html">Institut für Pathologie</a></p><p><b>title</b>: Histopathologischer Befundbericht — BET Mamma links mit SLN-Biopsie Axilla</p><h3>Attesters</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Mode</b></td><td><b>Party</b></td></tr><tr><td style="display: none">*</td><td>Legal</td><td><a href="Organization-PathologyLabOrganization.html">Organization Institut für Pathologie</a></td></tr></table><p><b>custodian</b>: <a href="Organization-PathologyLabOrganization.html">Organization Institut für Pathologie</a></p><h3>Events</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Detail</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://terminology.hl7.org/CodeSystem/v3-ActCode PATREPE}">pathology report entry task</span></td><td><a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></td></tr></table></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="ACSN"/>
              <display value="Accession ID"/>
            </coding>
          </type>
          <system value="http://example.hospital.de/pathology-reports"/>
          <value value="PATH-COMP-2025-300"/>
        </identifier>
        <status value="final"/>
        <type>
          <coding>
            <system value="http://ihe-d.de/CodeSystems/IHEXDStypeCode"/>
            <code value="PATH"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371528001"/>
            <display value="Pathology report (record artifact)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
          <display value="Sabine Becker, geb. 15.03.1971 (PAT-2025-105)"/>
        </subject>
        <encounter>🔗 
          <reference value="Encounter/IntegratedEncounter"/>
        </encounter>
        <date value="2025-02-10T17:00:00+01:00"/>
        <author>🔗 
          <reference value="Organization/PathologyLabOrganization"/>
          <display value="Institut für Pathologie"/>
        </author>
        <title
               value="Histopathologischer Befundbericht — BET Mamma links mit SLN-Biopsie Axilla"/>
        <attester>
          <mode value="legal"/>
          <party>🔗 
            <reference value="Organization/PathologyLabOrganization"/>
          </party>
        </attester>
        <custodian>🔗 
          <reference value="Organization/PathologyLabOrganization"/>
        </custodian>
        <event>
          <code>
            <coding>
              <system
                      value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/>
              <code value="PATREPE"/>
            </coding>
          </code>
          <detail>🔗 
            <reference value="ServiceRequest/IntegratedReportRequest"/>
          </detail>
        </event>
        <section>
          <title value="Pathologiebefundbericht"/>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="11526-1"/>
              <display value="Pathology study"/>
            </coding>
          </code>
          <text>
            <status value="additional"/>
            <div xmlns="http://www.w3.org/1999/xhtml"><h3>Klinische Angaben</h3><p>Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links mit SLN-Biopsie Axilla indiziert. Drahthäkchenmarkierung. Keine neoadjuvante Therapie. Ersterkrankung. Keine bekannte genetische Prädisposition. Präparateradiographie beigelegt. Axilla klinisch unauffällig (cN0).</p><h3>Material</h3><p><b>A) BET-Exzisionspräparat:</b> Mamma links, mit Haut, Drahthäkchen in situ</p><p><b>B) SLN-Exzisat:</b> Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert)</p><h3>Makroskopie Mamma</h3><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>Größe</td><td>42 × 35 × 18 mm</td></tr><tr><td>Gewicht</td><td>10 g</td></tr><tr><td>Quadrant</td><td>Unterer äußerer Quadrant</td></tr><tr><td>Zifferblatt</td><td>5 Uhr</td></tr><tr><td>Abstand Mamille</td><td>50 mm</td></tr><tr><td>Lamellierung</td><td>8 Scheiben à 5 mm</td></tr><tr><td>Schnittfläche</td><td>Grau-weißlich, derber Herdbefund zentral in Scheibe III–V, ca. 18 mm</td></tr><tr><td>Paraffinblöcke</td><td>6</td></tr></tbody></table><h3>Makroskopie Axilla</h3><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>SLN #1</td><td>12 × 8 × 6 mm, Patentblau-markiert, halbiert</td></tr><tr><td>SLN #2</td><td>10 × 7 × 5 mm, Patentblau-markiert, halbiert</td></tr><tr><td>Einbettung</td><td>Beide SLN vollständig eingebettet, je 1 Paraffinblock</td></tr></tbody></table><h3>Schnellschnitt</h3><p>SLN #1: Tumorfrei im Schnellschnitt. SLN #2: Tumorfrei im Schnellschnitt. → Keine Axilladissektion.</p><p><i>Hinweis: Mikrometastase in SLN #1 erst in den Paraffinschnittstufen nachgewiesen.</i></p><h3>Mikroskopie Mamma</h3><p>Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.</p><h3>Mikroskopie Axilla</h3><p>SLN #1: Im Randsinus Nachweis einer Mikrometastase, maximal 1,2 mm messend. Keine Kapseldurchbrechung. SLN #2: In allen Schnittstufen tumorfrei. Kein Anhalt für isolierte Tumorzellen (ITC).</p><h3>Diagnostische Schlussfolgerung</h3><p><b>Diagnose:</b> Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c pN1mi(sn)</p><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>ICD-10</td><td>C50.5</td></tr><tr><td>ICD-O-3 Morphologie</td><td>M8500/3</td></tr><tr><td>Operatives Verfahren</td><td>BET (brusterhaltende Therapie) mit SLN-Biopsie</td></tr><tr><td>Seitenlokalisation</td><td>Links</td></tr><tr><td>Fokalität</td><td>Unifokal</td></tr><tr><td>Max. Durchmesser invasiv</td><td>18 mm</td></tr><tr><td>Max. Gesamtdurchmesser</td><td>22 mm</td></tr><tr><td>Nottingham-Grad</td><td>Grad 2 (Score 6: Tubuli 3, Pleomorphie 2, Mitosen 1)</td></tr><tr><td>Assoziiertes DCIS</td><td>Vorhanden, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen</td></tr><tr><td>Tumorausdehnung</td><td>Auf Brustdrüse beschränkt</td></tr></tbody></table><h4>Resektionsränder</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>RR-Status invasiv</td><td>Nicht befallen (R0)</td></tr><tr><td>Nächster tumorfreier RR</td><td>Posterior</td></tr><tr><td>Mindestabstand invasiv</td><td>5 mm</td></tr><tr><td>RR-Status DCIS</td><td>Nicht befallen</td></tr><tr><td>Mindestabstand DCIS</td><td>3 mm</td></tr></tbody></table><h4>Axilläre Lymphknoten</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>Prozedur</td><td>Sentinel-Lymphknoten-Biopsie</td></tr><tr><td>Untersuchte SLN</td><td>2</td></tr><tr><td>Befallene SLN</td><td>1</td></tr><tr><td>Untersuchte Non-SLN</td><td>0</td></tr><tr><td>Befallene Non-SLN</td><td>0</td></tr><tr><td>Gesamtzahl untersuchter LK</td><td>2</td></tr><tr><td>Gesamtzahl befallener LK</td><td>1</td></tr><tr><td>Makrometastasen</td><td>0</td></tr><tr><td>Mikrometastasen</td><td>1</td></tr><tr><td>ITC</td><td>0</td></tr><tr><td>Größte Metastasenausdehnung</td><td>1,2 mm</td></tr><tr><td>Extranodale Infiltration</td><td>Nicht vorhanden</td></tr></tbody></table><h4>Biomarker</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>ER</td><td>Positiv (90%, stark)</td></tr><tr><td>PR</td><td>Positiv (60%, mäßig)</td></tr><tr><td>HER2 (IHC)</td><td>1+</td></tr><tr><td>HER2 (ISH)</td><td>Nicht amplifiziert</td></tr><tr><td>HER2-Gesamtstatus</td><td>Negativ</td></tr><tr><td>Ki-67</td><td>15%</td></tr></tbody></table><h4>Weitere Befunde</h4><table border="1" cellpadding="4" cellspacing="0"><tbody><tr><td>Lymphgefäßinvasion</td><td>Nicht nachgewiesen</td></tr><tr><td>Mikrokalzifikationen</td><td>In DCIS assoziiert</td></tr></tbody></table><h4>TNM-Staging</h4><p><b>pT1c pN1mi(sn)</b></p><p><b>Kommentar:</b> Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. SLN #1 mit Mikrometastase (1,2 mm), erst in Paraffinschnittstufen nachgewiesen (Schnellschnitt war tumorfrei). Keine extranodale Infiltration. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</p></div>
          </text>
          <entry>🔗 
            <reference value="DiagnosticReport/IntegratedReport"/>
          </entry>
        </section>
      </Composition>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Patient/Patient4"/>
    <resource>
      <Patient>
        <id value="Patient4"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_Patient4"> </a><p class="res-header-id"><b>Generated Narrative: Patient Patient4</b></p><a name="Patient4"> </a><a name="hcPatient4"> </a><p style="border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</p><hr/></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/patient-ids"/>
          <value value="PAT-2025-105"/>
        </identifier>
        <name>
          <family value="Becker"/>
          <given value="Sabine"/>
        </name>
        <gender value="female"/>
        <birthDate value="1971-03-15"/>
      </Patient>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Organization/PathologyLabOrganization"/>
    <resource>
      <Organization>
        <id value="PathologyLabOrganization"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_PathologyLabOrganization"> </a><p class="res-header-id"><b>Generated Narrative: Organization PathologyLabOrganization</b></p><a name="PathologyLabOrganization"> </a><a name="hcPathologyLabOrganization"> </a><p><b>identifier</b>: <code>http://example.hospital.de/organization-ids</code>/ORG-PATH-001</p><p><b>name</b>: Institut für Pathologie</p></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/organization-ids"/>
          <value value="ORG-PATH-001"/>
        </identifier>
        <name value="Institut für Pathologie"/>
      </Organization>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Practitioner/PathologistPractitioner"/>
    <resource>
      <Practitioner>
        <id value="PathologistPractitioner"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Practitioner_PathologistPractitioner"> </a><p class="res-header-id"><b>Generated Narrative: Practitioner PathologistPractitioner</b></p><a name="PathologistPractitioner"> </a><a name="hcPathologistPractitioner"> </a><p><b>identifier</b>: <code>http://example.hospital.de/practitioner-ids</code>/PATH-001</p><p><b>name</b>: Elisabeth Hoffmann </p><h3>Qualifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 394595002}">Pathology</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/practitioner-ids"/>
          <value value="PATH-001"/>
        </identifier>
        <name>
          <family value="Hoffmann"/>
          <given value="Elisabeth"/>
          <prefix value="Dr."/>
        </name>
        <qualification>
          <code>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="394595002"/>
              <display value="Pathology"/>
            </coding>
          </code>
        </qualification>
      </Practitioner>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Practitioner/BreastSurgeonPractitioner"/>
    <resource>
      <Practitioner>
        <id value="BreastSurgeonPractitioner"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Practitioner_BreastSurgeonPractitioner"> </a><p class="res-header-id"><b>Generated Narrative: Practitioner BreastSurgeonPractitioner</b></p><a name="BreastSurgeonPractitioner"> </a><a name="hcBreastSurgeonPractitioner"> </a><p><b>identifier</b>: <code>http://example.hospital.de/practitioner-ids</code>/GYN-001</p><p><b>name</b>: Thomas Richter </p><h3>Qualifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 394586005}">Gynecology</span></td></tr></table></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/practitioner-ids"/>
          <value value="GYN-001"/>
        </identifier>
        <name>
          <family value="Richter"/>
          <given value="Thomas"/>
          <prefix value="Prof. Dr."/>
        </name>
        <qualification>
          <code>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="394586005"/>
              <display value="Gynecology"/>
            </coding>
          </code>
        </qualification>
      </Practitioner>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Encounter/IntegratedEncounter"/>
    <resource>
      <Encounter>
        <id value="IntegratedEncounter"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Encounter_IntegratedEncounter"> </a><p class="res-header-id"><b>Generated Narrative: Encounter IntegratedEncounter</b></p><a name="IntegratedEncounter"> </a><a name="hcIntegratedEncounter"> </a><p><b>identifier</b>: <code>http://example.hospital.de/encounters</code>/E_25_300</p><p><b>status</b>: Finished</p><p><b>class</b>: [not stated]: IMP (IMP)</p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p></div>
        </text>
        <identifier>
          <system value="http://example.hospital.de/encounters"/>
          <value value="E_25_300"/>
        </identifier>
        <status value="finished"/>
        <class>
          <code value="IMP"/>
        </class>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
      </Encounter>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Condition/IntegratedDiagnosisConfirmed"/>
    <resource>
      <Condition>
        <id value="IntegratedDiagnosisConfirmed"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/StructureDefinition/Diagnose|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Condition_IntegratedDiagnosisConfirmed"> </a><p class="res-header-id"><b>Generated Narrative: Condition IntegratedDiagnosisConfirmed</b></p><a name="IntegratedDiagnosisConfirmed"> </a><a name="hcIntegratedDiagnosisConfirmed"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.molgen@2026.0.4&amp;canonical=https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/StructureDefinition/Diagnose">MII PR Diagnose Condition</a> version: 2026.0.0</p></div><p><b>clinicalStatus</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/condition-clinical active}">Active</span></p><p><b>verificationStatus</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/condition-ver-status confirmed}">Confirmed</span></p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/condition-category encounter-diagnosis}">Encounter Diagnosis</span></p><p><b>code</b>: <span title="Codes:{http://fhir.de/CodeSystem/bfarm/icd-10-gm C50.5}">Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>encounter</b>: <a href="Encounter-IntegratedEncounter.html">Encounter: identifier = http://example.hospital.de/encounters#E_25_300; status = finished; class = IMP (IMP)</a></p><p><b>onset</b>: 2025-01-15</p><p><b>recordedDate</b>: 2025-02-05</p><p><b>note</b>: </p><blockquote><div><p>Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links mit SLN-Biopsie Axilla indiziert.</p>
</div></blockquote></div>
        </text>
        <clinicalStatus>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/condition-clinical"/>
            <code value="active"/>
          </coding>
        </clinicalStatus>
        <verificationStatus>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/condition-ver-status"/>
            <code value="confirmed"/>
          </coding>
        </verificationStatus>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/condition-category"/>
            <code value="encounter-diagnosis"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://fhir.de/CodeSystem/bfarm/icd-10-gm"/>
            <version value="2025"/>
            <code value="C50.5"/>
            <display
                     value="Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <encounter>🔗 
          <reference value="Encounter/IntegratedEncounter"/>
        </encounter>
        <onsetDateTime value="2025-01-15"/>
        <recordedDate value="2025-02-05"/>
        <note>
          <text
                value="Z.n. Stanzbiopsie (E_25_105) mit Nachweis eines invasiven Mammakarzinoms NST, G2. BI-RADS 4b. BET links mit SLN-Biopsie Axilla indiziert."/>
        </note>
      </Condition>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/ServiceRequest/IntegratedReportRequest"/>
    <resource>
      <ServiceRequest>
        <id value="IntegratedReportRequest"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-service-request|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="ServiceRequest_IntegratedReportRequest"> </a><p class="res-header-id"><b>Generated Narrative: ServiceRequest IntegratedReportRequest</b></p><a name="IntegratedReportRequest"> </a><a name="hcIntegratedReportRequest"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-service-request">MII PR Patho Service Request</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/PATH-RPT-2025-300</p><p><b>status</b>: Completed</p><p><b>intent</b>: Order</p><p><b>category</b>: <span title="Codes:{http://snomed.info/sct 726007}">Pathology consultation, comprehensive, records and specimen with report (procedure)</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 60568-3}">Pathology synoptic report</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>encounter</b>: <a href="Encounter-IntegratedEncounter.html">Encounter: identifier = http://example.hospital.de/encounters#E_25_300; status = finished; class = IMP (IMP)</a></p><p><b>requester</b>: <a href="Practitioner-BreastSurgeonPractitioner.html">Practitioner Thomas Richter </a></p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>reasonCode</b>: <span title="Codes:{http://snomed.info/sct 254837009}">Malignant neoplasm of breast (disorder)</span></p><p><b>supportingInfo</b>: </p><ul><li><a href="Condition-IntegratedDiagnosisConfirmed.html">Condition Bösartige Neubildung: Unterer äußerer Quadrant der Brustdrüse</a></li><li><a href="DiagnosticReport-IntegratedImagingReport.html">Diagnostic Report for 'MG Breast Screening' for '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href="Observation-IntegratedCancerHistory.html">Observation Personal history of primary malignant neoplasm of breast (situation)</a></li><li><a href="Observation-IntegratedPriorTherapy.html">Observation Cancer treatment --preoperative</a></li><li><a href="Observation-IntegratedRadiologicalExtent.html">Observation Lesion size, largest dimension (observable entity)</a></li><li><a href="Observation-IntegratedSpecimenMarking.html">Observation Insertion of marker into breast using X-ray guidance (procedure)</a></li><li><a href="Observation-IntegratedSpecimenRadiographyClinical.html">Observation 80865008|Specimen mammography|:363702006|Has focus|=185008008|Medical reports sent|</a></li><li><a href="Observation-IntegratedGeneticPredisposition.html">Observation Diathesis, function (observable entity)</a></li></ul><p><b>specimen</b>: </p><ul><li><a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></li><li><a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></li></ul></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="PLAC"/>
              <display value="Placer Identifier"/>
            </coding>
          </type>
          <system value="http://example.hospital.de/serviceRequest"/>
          <value value="PATH-RPT-2025-300"/>
        </identifier>
        <status value="completed"/>
        <intent value="order"/>
        <category>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="726007"/>
            <display
                     value="Pathology consultation, comprehensive, records and specimen with report (procedure)"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="60568-3"/>
            <display value="Pathology synoptic report"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <encounter>🔗 
          <reference value="Encounter/IntegratedEncounter"/>
        </encounter>
        <requester>🔗 
          <reference value="Practitioner/BreastSurgeonPractitioner"/>
        </requester>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <reasonCode>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="254837009"/>
            <display value="Malignant neoplasm of breast (disorder)"/>
          </coding>
        </reasonCode>
        <supportingInfo>🔗 
          <reference value="Condition/IntegratedDiagnosisConfirmed"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference value="DiagnosticReport/IntegratedImagingReport"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference value="Observation/IntegratedCancerHistory"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference value="Observation/IntegratedPriorTherapy"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference value="Observation/IntegratedRadiologicalExtent"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference value="Observation/IntegratedSpecimenMarking"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference
                     value="Observation/IntegratedSpecimenRadiographyClinical"/>
        </supportingInfo>
        <supportingInfo>🔗 
          <reference value="Observation/IntegratedGeneticPredisposition"/>
        </supportingInfo>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
      </ServiceRequest>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/DiagnosticReport/IntegratedImagingReport"/>
    <resource>
      <DiagnosticReport>
        <id value="IntegratedImagingReport"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_IntegratedImagingReport"> </a><p class="res-header-id"><b>Generated Narrative: DiagnosticReport IntegratedImagingReport</b></p><a name="IntegratedImagingReport"> </a><a name="hcIntegratedImagingReport"> </a><h2><span title="Codes:{http://loinc.org 24606-6}">MG Breast Screening</span> (<span title="Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 RAD}">Radiology</span>) </h2><table class="grid"><tr><td>Subject</td><td>Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</td></tr><tr><td>When For</td><td>2025-01-08</td></tr></table><p><b>Report Details</b></p><p>BI-RADS 4b: Herdbefund linke Brust, unterer äußerer Quadrant, 5 Uhr, 5 cm von Mamille. Radiologische Ausdehnung ca. 15 mm. Mammografie und Ultraschall. Klinisch unauffällige Axilla (cN0). Indikation zur BET mit SLN-Biopsie.</p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/v2-0074"/>
            <code value="RAD"/>
            <display value="Radiology"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="24606-6"/>
            <display value="MG Breast Screening"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-01-08"/>
        <conclusion
                    value="BI-RADS 4b: Herdbefund linke Brust, unterer äußerer Quadrant, 5 Uhr, 5 cm von Mamille. Radiologische Ausdehnung ca. 15 mm. Mammografie und Ultraschall. Klinisch unauffällige Axilla (cN0). Indikation zur BET mit SLN-Biopsie."/>
      </DiagnosticReport>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedCancerHistory"/>
    <resource>
      <Observation>
        <id value="IntegratedCancerHistory"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedCancerHistory"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedCancerHistory</b></p><a name="IntegratedCancerHistory"> </a><a name="hcIntegratedCancerHistory"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 415076002}">Brustkrebsvorgeschichte</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:">Ersterkrankung</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="415076002"/>
            <display
                     value="Personal history of primary malignant neoplasm of breast (situation)"/>
          </coding>
          <text value="Brustkrebsvorgeschichte"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <text value="Ersterkrankung"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedPriorTherapy"/>
    <resource>
      <Observation>
        <id value="IntegratedPriorTherapy"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedPriorTherapy"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedPriorTherapy</b></p><a name="IntegratedPriorTherapy"> </a><a name="hcIntegratedPriorTherapy"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://loinc.org 81167-9}">Vorchirurgische Therapie bei invasivem Karzinom</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 373067005}">Keine neoadjuvante Therapie</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="81167-9"/>
            <display value="Cancer treatment --preoperative"/>
          </coding>
          <text value="Vorchirurgische Therapie bei invasivem Karzinom"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="373067005"/>
            <display value="No (qualifier value)"/>
          </coding>
          <text value="Keine neoadjuvante Therapie"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedRadiologicalExtent"/>
    <resource>
      <Observation>
        <id value="IntegratedRadiologicalExtent"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedRadiologicalExtent"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedRadiologicalExtent</b></p><a name="IntegratedRadiologicalExtent"> </a><a name="hcIntegratedRadiologicalExtent"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 396361002}">Radiologische Ausdehnung</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: 15 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="396361002"/>
            <display
                     value="Lesion size, largest dimension (observable entity)"/>
          </coding>
          <text value="Radiologische Ausdehnung"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <valueQuantity>
          <value value="15"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedSpecimenMarking"/>
    <resource>
      <Observation>
        <id value="IntegratedSpecimenMarking"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedSpecimenMarking"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedSpecimenMarking</b></p><a name="IntegratedSpecimenMarking"> </a><a name="hcIntegratedSpecimenMarking"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 836381000000102}">Befundmarkierung</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:">Drahthäkchen</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="836381000000102"/>
            <display
                     value="Insertion of marker into breast using X-ray guidance (procedure)"/>
          </coding>
          <text value="Befundmarkierung"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <text value="Drahthäkchen"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedSpecimenRadiographyClinical"/>
    <resource>
      <Observation>
        <id value="IntegratedSpecimenRadiographyClinical"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedSpecimenRadiographyClinical"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedSpecimenRadiographyClinical</b></p><a name="IntegratedSpecimenRadiographyClinical"> </a><a name="hcIntegratedSpecimenRadiographyClinical"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 80865008:363702006=185008008}">Präparateradiographie beigelegt</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 52101004}">Ja, beigelegt</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="80865008:363702006=185008008"/>
            <display
                     value="80865008|Specimen mammography|:363702006|Has focus|=185008008|Medical reports sent|"/>
          </coding>
          <text value="Präparateradiographie beigelegt"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="52101004"/>
            <display value="Present (qualifier value)"/>
          </coding>
          <text value="Ja, beigelegt"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedGeneticPredisposition"/>
    <resource>
      <Observation>
        <id value="IntegratedGeneticPredisposition"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedGeneticPredisposition"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedGeneticPredisposition</b></p><a name="IntegratedGeneticPredisposition"> </a><a name="hcIntegratedGeneticPredisposition"> </a><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 76522002}">Genetische Prädisposition</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 261665006}">Nicht bekannt</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76522002"/>
            <display value="Diathesis, function (observable entity)"/>
          </coding>
          <text value="Genetische Prädisposition"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="261665006"/>
            <display value="Unknown (qualifier value)"/>
          </coding>
          <text value="Nicht bekannt"/>
        </valueCodeableConcept>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/DiagnosticReport/IntegratedReport"/>
    <resource>
      <DiagnosticReport>
        <id value="IntegratedReport"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-report|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_IntegratedReport"> </a><p class="res-header-id"><b>Generated Narrative: DiagnosticReport IntegratedReport</b></p><a name="IntegratedReport"> </a><a name="hcIntegratedReport"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-report">MII PR Patho Report</a> version: 2026.0.0</p></div><h2><span title="Codes:{http://loinc.org 60568-3}">Pathology Synoptic report</span> (<span title="Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 SP}">Surgical Pathology</span>) </h2><table class="grid"><tr><td>Subject</td><td>Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</td></tr><tr><td>When For</td><td>2025-02-10 14:00:00+0100</td></tr><tr><td>Reported</td><td>2025-02-10 17:00:00+0100</td></tr><tr><td>Performer</td><td> <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></td></tr><tr><td>Identifier</td><td> Accession ID/E_25_300</td></tr></table><p><b>Report Details</b></p><table class="grid"><tr><td><b>Code</b></td><td><b>Value</b></td><td><b>Flags</b></td><td><b>When For</b></td></tr><tr><td><a href="Observation-IntegratedMacroscopicGrouper.html"><span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></a></td><td/><td>Final</td><td>2025-02-06 08:30:00+0100</td></tr><tr><td><a href="Observation-IntegratedDiagnosticConclusionGrouper.html"><span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></a></td><td/><td>Final</td><td>2025-02-10</td></tr></table><p>Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c pN1mi(sn), Nottingham Grad 2 (Score 6: Tubuli 3, Kernpleomorphie 2, Mitosen 1). Begleitendes DCIS, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen. Alle Resektionsränder tumorfrei (invasiv 5 mm, DCIS 3 mm). Keine LVI. ER+ (90%), PR+ (60%), HER2 1+ (nicht amplifiziert), Ki-67 15%. SLN 1/2 befallen (Mikrometastase 1,2 mm in SLN #1), keine extranodale Infiltration.</p></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="ACSN"/>
              <display value="Accession ID"/>
            </coding>
          </type>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </identifier>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system value="http://terminology.hl7.org/CodeSystem/v2-0074"/>
            <code value="SP"/>
            <display value="Surgical Pathology"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="60568-3"/>
            <display value="Pathology Synoptic report"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10T14:00:00+01:00"/>
        <issued value="2025-02-10T17:00:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock02"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock03"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock04"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock05"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock06"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE02"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideER01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlidePR01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHER2IHC01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideKi67-01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideCK18-01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlidep40-01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideECad-01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideBlock02-HE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideBlock02-HE02"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Superior-HE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Inferior-HE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Medial-HE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Lateral-HE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock02"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSlideHE01"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSlideHE02"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSlideHE03"/>
        </specimen>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSlideHE04"/>
        </specimen>
        <result>🔗 
          <reference value="Observation/IntegratedMacroscopicGrouper"/>
        </result>
        <result>🔗 
          <reference
                     value="Observation/IntegratedDiagnosticConclusionGrouper"/>
        </result>
        <conclusion
                    value="Invasives Mammakarzinom NST (ICD-O 8500/3), pT1c pN1mi(sn), Nottingham Grad 2 (Score 6: Tubuli 3, Kernpleomorphie 2, Mitosen 1). Begleitendes DCIS, intermediärer Kerngrad, kribriform, fokale Komedo-Nekrosen. Alle Resektionsränder tumorfrei (invasiv 5 mm, DCIS 3 mm). Keine LVI. ER+ (90%), PR+ (60%), HER2 1+ (nicht amplifiziert), Ki-67 15%. SLN 1/2 befallen (Mikrometastase 1,2 mm in SLN #1), keine extranodale Infiltration."/>
      </DiagnosticReport>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSpecimenPart"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenPart"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenPart"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenPart</b></p><a name="IntegratedBETSpecimenPart"> </a><a name="hcIntegratedBETSpecimenPart"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/OP25_300_A, Filler Identifier/E_25_300_A</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 397199005}">Specimen from breast obtained by excision (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>request</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collector</b></td><td><b>Collected[x]</b></td><td><b>Method</b></td><td><b>BodySite</b></td></tr><tr><td style="display: none">*</td><td><a href="Practitioner-BreastSurgeonPractitioner.html">Practitioner Thomas Richter </a></td><td>2025-02-05 10:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 237371007}">Wide local excision of breast lesion (procedure)</span></td><td><span title="Codes:{http://snomed.info/sct 33564002}">Structure of lower outer quadrant of breast (body structure)</span></td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 434746001}">Specimen vial (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 434162003}">Neutral buffered formalin (substance)</span></td></tr></table><p><b>note</b>: </p><blockquote><div><p>BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</p>
</div></blockquote></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="PLAC"/>
            </coding>
          </type>
          <system
                  value="https://senologie.example-hospital.de/fhir/specimen/placer"/>
          <value value="OP25_300_A"/>
        </identifier>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="FILL"/>
            </coding>
          </type>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="397199005"/>
            <display
                     value="Specimen from breast obtained by excision (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <request>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </request>
        <collection>
          <collector>🔗 
            <reference value="Practitioner/BreastSurgeonPractitioner"/>
          </collector>
          <collectedDateTime value="2025-02-05T10:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="237371007"/>
              <display
                       value="Wide local excision of breast lesion (procedure)"/>
            </coding>
          </method>
          <bodySite>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="33564002"/>
              <display
                       value="Structure of lower outer quadrant of breast (body structure)"/>
            </coding>
          </bodySite>
        </collection>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434746001"/>
              <display value="Specimen vial (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434162003"/>
              <display value="Neutral buffered formalin (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
        <note>
          <text
                value="BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm."/>
        </note>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenBlock01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenBlock01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock01</b></p><a name="IntegratedBETSpecimenBlock01"> </a><a name="hcIntegratedBETSpecimenBlock01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe III</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:00:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
                       value="Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe III"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
                       value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock02"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenBlock02"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenBlock02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock02</b></p><a name="IntegratedBETSpecimenBlock02"> </a><a name="hcIntegratedBETSpecimenBlock02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_2</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:10:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe V</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:10:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_2"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:10:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
                       value="Zuschnitt und Paraffineinbettung - Tumor zentral, Scheibe V"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
                       value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:10:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock03"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenBlock03"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenBlock03"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock03</b></p><a name="IntegratedBETSpecimenBlock03"> </a><a name="hcIntegratedBETSpecimenBlock03"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_3</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:20:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR superior</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:20:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
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          <value value="E_25_300_A_3"/>
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        <accessionIdentifier>
          <system
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          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:20:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
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            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
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              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
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          <description
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          <procedure>
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              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
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          <timeDateTime value="2025-02-06T08:20:00+01:00"/>
        </processing>
        <container>
          <type>
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              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
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          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
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          </additiveCodeableConcept>
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      </Specimen>
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  </entry>
  <entry>
    <fullUrl
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    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenBlock04"/>
        <meta>
          <profile
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          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenBlock04"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock04</b></p><a name="IntegratedBETSpecimenBlock04"> </a><a name="hcIntegratedBETSpecimenBlock04"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_4</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR inferior</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:30:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_4"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
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          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
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            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:30:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock05"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenBlock05"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenBlock05"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock05</b></p><a name="IntegratedBETSpecimenBlock05"> </a><a name="hcIntegratedBETSpecimenBlock05"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_5</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:40:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR medial, Scheibe I</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:40:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_5"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:40:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
                       value="Zuschnitt und Paraffineinbettung - RR medial, Scheibe I"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
                       value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:40:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSpecimenBlock06"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSpecimenBlock06"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSpecimenBlock06"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSpecimenBlock06</b></p><a name="IntegratedBETSpecimenBlock06"> </a><a name="hcIntegratedBETSpecimenBlock06"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_6</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:50:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - RR lateral, Scheibe VIII</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:50:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
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          <value value="E_25_300_A_6"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:50:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
                       value="Zuschnitt und Paraffineinbettung - RR lateral, Scheibe VIII"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
                       value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:50:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideHE01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideHE01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideHE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideHE01</b></p><a name="IntegratedBETSlideHE01"> </a><a name="hcIntegratedBETSlideHE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 1)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideHE02"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideHE02"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideHE02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideHE02</b></p><a name="IntegratedBETSlideHE02"> </a><a name="hcIntegratedBETSlideHE02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_HE_02"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 2)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideER01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideER01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideER01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideER01</b></p><a name="IntegratedBETSlideER01"> </a><a name="hcIntegratedBETSlideER01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_ER_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: ER-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstanceER.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_ER_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
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            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="ER-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstanceER"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
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    <resource>
      <Specimen>
        <id value="IntegratedBETSlidePR01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlidePR01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlidePR01</b></p><a name="IntegratedBETSlidePR01"> </a><a name="hcIntegratedBETSlidePR01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_PR_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: PR-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstancePR.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_PR_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="PR-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstancePR"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideHER2IHC01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideHER2IHC01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideHER2IHC01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideHER2IHC01</b></p><a name="IntegratedBETSlideHER2IHC01"> </a><a name="hcIntegratedBETSlideHER2IHC01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_HER2_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HER2-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstanceHER2IHC.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_HER2_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HER2-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstanceHER2IHC"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideKi67-01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideKi67-01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideKi67-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideKi67-01</b></p><a name="IntegratedBETSlideKi67-01"> </a><a name="hcIntegratedBETSlideKi67-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_Ki67_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Ki-67-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstanceKi67.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_Ki67_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Ki-67-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstanceKi67"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
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    <resource>
      <Specimen>
        <id value="IntegratedBETSlideCK18-01"/>
        <meta>
          <profile
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          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideCK18-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideCK18-01</b></p><a name="IntegratedBETSlideCK18-01"> </a><a name="hcIntegratedBETSlideCK18-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_CK18_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: CK18-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstanceCK18.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_CK18_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="CK18-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstanceCK18"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlidep40-01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlidep40-01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlidep40-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlidep40-01</b></p><a name="IntegratedBETSlidep40-01"> </a><a name="hcIntegratedBETSlidep40-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_p40_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: p40-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstancep40.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_p40_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="p40-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstancep40"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideECad-01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideECad-01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideECad-01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideECad-01</b></p><a name="IntegratedBETSlideECad-01"> </a><a name="hcIntegratedBETSlideECad-01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_1_1_ECad_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:30:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: E-Cadherin-Immunhistochemie</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 117617002}">Immunohistochemistry procedure (procedure)</span></p><p><b>additive</b>: <a href="Substance-IntegratedSubstanceECadherin.html">Substance Tissue stain (substance)</a></p><p><b>time</b>: 2025-02-06 10:00:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_1_1_ECad_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:30:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="E-Cadherin-Immunhistochemie"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="117617002"/>
              <display value="Immunohistochemistry procedure (procedure)"/>
            </coding>
          </procedure>
          <additive>🔗 
            <reference value="Substance/IntegratedSubstanceECadherin"/>
          </additive>
          <timeDateTime value="2025-02-06T10:00:00+01:00"/>
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            <coding>
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              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
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          <additiveCodeableConcept>
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              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
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          <profile
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        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideBlock02-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideBlock02-HE01</b></p><a name="IntegratedBETSlideBlock02-HE01"> </a><a name="hcIntegratedBETSlideBlock02-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_2_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
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          <value value="E_25_300_A_2_1_HE_01"/>
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        <accessionIdentifier>
          <system
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          <value value="E_25_300"/>
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        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock02"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
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            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
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              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 1)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
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            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
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                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
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          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
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        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
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          <additiveCodeableConcept>
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              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
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          </additiveCodeableConcept>
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  </entry>
  <entry>
    <fullUrl
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    <resource>
      <Specimen>
        <id value="IntegratedBETSlideBlock02-HE02"/>
        <meta>
          <profile
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          <profile
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        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideBlock02-HE02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideBlock02-HE02</b></p><a name="IntegratedBETSlideBlock02-HE02"> </a><a name="hcIntegratedBETSlideBlock02-HE02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_2_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_2_1_HE_02"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock02"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 2)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
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            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
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          <additiveCodeableConcept>
            <coding>
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              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedBETSlideRR-Superior-HE01"/>
    <resource>
      <Specimen>
        <id value="IntegratedBETSlideRR-Superior-HE01"/>
        <meta>
          <profile
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          <profile
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        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideRR-Superior-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideRR-Superior-HE01</b></p><a name="IntegratedBETSlideRR-Superior-HE01"> </a><a name="hcIntegratedBETSlideRR-Superior-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_3_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock03.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_A_3_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock03"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
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            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
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          <additiveCodeableConcept>
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              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
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          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
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    <resource>
      <Specimen>
        <id value="IntegratedBETSlideRR-Inferior-HE01"/>
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        <text>
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        <subject>🔗 
          <reference value="Patient/Patient4"/>
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        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock04"/>
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        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
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          <description value="Schnittherstellung"/>
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          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
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        <processing>
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          <description value="HE-Färbung"/>
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        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideRR-Medial-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideRR-Medial-HE01</b></p><a name="IntegratedBETSlideRR-Medial-HE01"> </a><a name="hcIntegratedBETSlideRR-Medial-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_5_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock05.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_5; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
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          <value value="E_25_300_A_5_1_HE_01"/>
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        <status value="available"/>
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            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
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        <subject>🔗 
          <reference value="Patient/Patient4"/>
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        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock05"/>
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        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
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            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
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                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
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          <description value="Schnittherstellung"/>
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            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
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          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
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  <entry>
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    <resource>
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        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedBETSlideRR-Lateral-HE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedBETSlideRR-Lateral-HE01</b></p><a name="IntegratedBETSlideRR-Lateral-HE01"> </a><a name="hcIntegratedBETSlideRR-Lateral-HE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_A_6_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedBETSpecimenBlock06.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_6; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
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          <value value="E_25_300_A_6_1_HE_01"/>
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        <accessionIdentifier>
          <system
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        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
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        <parent>🔗 
          <reference value="Specimen/IntegratedBETSpecimenBlock06"/>
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        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
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            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
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                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
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          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
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                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
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          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
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  <entry>
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    <resource>
      <Specimen>
        <id value="IntegratedSLNSpecimenPart"/>
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          <profile
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          <profile
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        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSpecimenPart"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSpecimenPart</b></p><a name="IntegratedSLNSpecimenPart"> </a><a name="hcIntegratedSLNSpecimenPart"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: Placer Identifier/OP25_300_B, Filler Identifier/E_25_300_B</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 258589002}">Lymph node specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>request</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collector</b></td><td><b>Collected[x]</b></td><td><b>Method</b></td><td><b>BodySite</b></td></tr><tr><td style="display: none">*</td><td><a href="Practitioner-BreastSurgeonPractitioner.html">Practitioner Thomas Richter </a></td><td>2025-02-05 10:30:00+0100</td><td><span title="Codes:{http://snomed.info/sct 396487001}">Sentinel lymph node biopsy (procedure)</span></td><td><span title="Codes:{http://snomed.info/sct 68171009}">Axillary lymph node structure (body structure)</span></td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 434746001}">Specimen vial (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 434162003}">Neutral buffered formalin (substance)</span></td></tr></table><p><b>note</b>: </p><blockquote><div><p>Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</p>
</div></blockquote></div>
        </text>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="PLAC"/>
            </coding>
          </type>
          <system
                  value="https://senologie.example-hospital.de/fhir/specimen/placer"/>
          <value value="OP25_300_B"/>
        </identifier>
        <identifier>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
              <code value="FILL"/>
            </coding>
          </type>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="258589002"/>
            <display value="Lymph node specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <request>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </request>
        <collection>
          <collector>🔗 
            <reference value="Practitioner/BreastSurgeonPractitioner"/>
          </collector>
          <collectedDateTime value="2025-02-05T10:30:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="396487001"/>
              <display value="Sentinel lymph node biopsy (procedure)"/>
            </coding>
          </method>
          <bodySite>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="68171009"/>
              <display
                       value="Axillary lymph node structure (body structure)"/>
            </coding>
          </bodySite>
        </collection>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434746001"/>
              <display value="Specimen vial (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434162003"/>
              <display value="Neutral buffered formalin (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
        <note>
          <text
                value="Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet."/>
        </note>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedSLNSpecimenBlock01"/>
    <resource>
      <Specimen>
        <id value="IntegratedSLNSpecimenBlock01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSpecimenBlock01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSpecimenBlock01</b></p><a name="IntegratedSLNSpecimenBlock01"> </a><a name="hcIntegratedSLNSpecimenBlock01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_1</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - SLN #1 (halbiert)</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:00:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B_1"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
                       value="Zuschnitt und Paraffineinbettung - SLN #1 (halbiert)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
                       value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:00:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedSLNSpecimenBlock02"/>
    <resource>
      <Specimen>
        <id value="IntegratedSLNSpecimenBlock02"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSpecimenBlock02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSpecimenBlock02</b></p><a name="IntegratedSLNSpecimenBlock02"> </a><a name="hcIntegratedSLNSpecimenBlock02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_2</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 1201985008}">Tissue block specimen (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 08:10:00+0100</td><td><span title="Codes:{http://snomed.info/sct 787377000}">Gross examination and sampling of tissue specimen (procedure)</span></td></tr></table><h3>Processings</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Description</b></td><td><b>Procedure</b></td><td><b>Time[x]</b></td></tr><tr><td style="display: none">*</td><td/><td>Zuschnitt und Paraffineinbettung - SLN #2 (halbiert)</td><td><span title="Codes:{http://snomed.info/sct 787376009}">Preparation of formalin fixed paraffin embedded tissue specimen (procedure)</span></td><td>2025-02-06 08:10:00+0100</td></tr></table><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 706053007}">General specimen container (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 311731000}">Paraffin wax (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B_2"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1201985008"/>
            <display value="Tissue block specimen (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T08:10:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787377000"/>
              <display
                       value="Gross examination and sampling of tissue specimen (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="2"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="8"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description
                       value="Zuschnitt und Paraffineinbettung - SLN #2 (halbiert)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="787376009"/>
              <display
                       value="Preparation of formalin fixed paraffin embedded tissue specimen (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T08:10:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="706053007"/>
              <display value="General specimen container (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="311731000"/>
              <display value="Paraffin wax (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE01"/>
    <resource>
      <Specimen>
        <id value="IntegratedSLNSlideHE01"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSlideHE01"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSlideHE01</b></p><a name="IntegratedSLNSlideHE01"> </a><a name="hcIntegratedSLNSlideHE01"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_1_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedSLNSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B_1_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 1)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE02"/>
    <resource>
      <Specimen>
        <id value="IntegratedSLNSlideHE02"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSlideHE02"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSlideHE02</b></p><a name="IntegratedSLNSlideHE02"> </a><a name="hcIntegratedSLNSlideHE02"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_1_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedSLNSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B_1_1_HE_02"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock01"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 2)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE03"/>
    <resource>
      <Specimen>
        <id value="IntegratedSLNSlideHE03"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSlideHE03"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSlideHE03</b></p><a name="IntegratedSLNSlideHE03"> </a><a name="hcIntegratedSLNSlideHE03"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_2_1_HE_01</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedSLNSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 1)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B_2_1_HE_01"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock02"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 1)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Specimen/IntegratedSLNSlideHE04"/>
    <resource>
      <Specimen>
        <id value="IntegratedSLNSlideHE04"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen|2026.0.0"/>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore|2026.0.0"/>
        </meta>
        <text>
          <status value="extensions"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Specimen_IntegratedSLNSlideHE04"> </a><p class="res-header-id"><b>Generated Narrative: Specimen IntegratedSLNSlideHE04</b></p><a name="IntegratedSLNSlideHE04"> </a><a name="hcIntegratedSLNSlideHE04"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen">MII PR Patho Specimen</a> version: 2026.0.0, <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore">MII PR Biobank Specimen Bioprobe Core</a> version: 2026.0.0</p></div><p><b>identifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300_B_2_1_HE_02</p><p><b>accessionIdentifier</b>: <code>https://pathologie.example-hospital.de/fhir/fn/befundbericht</code>/E_25_300</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 430856003}">Tissue section (specimen)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>parent</b>: <a href="Specimen-IntegratedSLNSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><h3>Collections</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Collected[x]</b></td><td><b>Method</b></td></tr><tr><td style="display: none">*</td><td>2025-02-06 09:00:00+0100</td><td><span title="Codes:{http://snomed.info/sct 13283003}">Tissue processing technique (procedure)</span></td></tr></table><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: Schnittherstellung (Schnittstufe 2)</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 434472006}">Sectioning of tissue block (procedure)</span></p><p><b>time</b>: 2025-02-06 09:00:00+0100</p></blockquote><blockquote><p><b>processing</b></p><p><b>MII EX Biobank Temperaturbedingungen</b>: 20-25 °C</p><p><b>description</b>: HE-Färbung</p><p><b>procedure</b>: <span title="Codes:{http://snomed.info/sct 104210008}">Hematoxylin and eosin stain method (procedure)</span></p><p><b>time</b>: 2025-02-06 09:15:00+0100</p></blockquote><h3>Containers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Additive[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 433466003}">Microscope slide (physical object)</span></td><td><span title="Codes:{http://snomed.info/sct 430862008}">Microscope slide mounting medium (substance)</span></td></tr></table></div>
        </text>
        <identifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300_B_2_1_HE_02"/>
        </identifier>
        <accessionIdentifier>
          <system
                  value="https://pathologie.example-hospital.de/fhir/fn/befundbericht"/>
          <value value="E_25_300"/>
        </accessionIdentifier>
        <status value="available"/>
        <type>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="430856003"/>
            <display value="Tissue section (specimen)"/>
          </coding>
        </type>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <parent>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock02"/>
        </parent>
        <collection>
          <collectedDateTime value="2025-02-06T09:00:00+01:00"/>
          <method>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="13283003"/>
              <display value="Tissue processing technique (procedure)"/>
            </coding>
          </method>
        </collection>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="Schnittherstellung (Schnittstufe 2)"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="434472006"/>
              <display value="Sectioning of tissue block (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:00:00+01:00"/>
        </processing>
        <processing>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
            <valueRange>
              <low>
                <value value="20"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </low>
              <high>
                <value value="25"/>
                <unit value="°C"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="Cel"/>
              </high>
            </valueRange>
          </extension>
          <description value="HE-Färbung"/>
          <procedure>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="104210008"/>
              <display
                       value="Hematoxylin and eosin stain method (procedure)"/>
            </coding>
          </procedure>
          <timeDateTime value="2025-02-06T09:15:00+01:00"/>
        </processing>
        <container>
          <type>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="433466003"/>
              <display value="Microscope slide (physical object)"/>
            </coding>
          </type>
          <additiveCodeableConcept>
            <coding>
              <system value="http://snomed.info/sct"/>
              <code value="430862008"/>
              <display value="Microscope slide mounting medium (substance)"/>
            </coding>
          </additiveCodeableConcept>
        </container>
      </Specimen>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstanceER"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstanceER"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstanceER"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstanceER</b></p><a name="IntegratedSubstanceER"> </a><a name="hcIntegratedSubstanceER"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Estrogen Receptor (Dako Omnis)</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Estrogen Receptor (Dako Omnis)"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstancePR"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstancePR"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstancePR"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstancePR</b></p><a name="IntegratedSubstancePR"> </a><a name="hcIntegratedSubstancePR"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Progesterone Receptor (Dako Omnis)</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Progesterone Receptor (Dako Omnis)"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstanceHER2IHC"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstanceHER2IHC"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstanceHER2IHC"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstanceHER2IHC</b></p><a name="IntegratedSubstanceHER2IHC"> </a><a name="hcIntegratedSubstanceHER2IHC"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: VENTANA HER2 (4B5), Roche</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="VENTANA HER2 (4B5), Roche"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstanceKi67"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstanceKi67"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstanceKi67"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstanceKi67</b></p><a name="IntegratedSubstanceKi67"> </a><a name="hcIntegratedSubstanceKi67"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Ki-67 Antigen (Dako Omnis)</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Ki-67 Antigen (Dako Omnis)"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstanceCK18"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstanceCK18"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstanceCK18"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstanceCK18</b></p><a name="IntegratedSubstanceCK18"> </a><a name="hcIntegratedSubstanceCK18"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: Cytokeratin 18 (DC10), Dako Omnis</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="Cytokeratin 18 (DC10), Dako Omnis"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstancep40"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstancep40"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstancep40"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstancep40</b></p><a name="IntegratedSubstancep40"> </a><a name="hcIntegratedSubstancep40"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: p40 (BC28), Biocare Medical</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="p40 (BC28), Biocare Medical"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Substance/IntegratedSubstanceECadherin"/>
    <resource>
      <Substance>
        <id value="IntegratedSubstanceECadherin"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_IntegratedSubstanceECadherin"> </a><p class="res-header-id"><b>Generated Narrative: Substance IntegratedSubstanceECadherin</b></p><a name="IntegratedSubstanceECadherin"> </a><a name="hcIntegratedSubstanceECadherin"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance">MII PR Biobank Substance Additiv</a> version: 2026.0.0</p></div><p><b>status</b>: Active</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/substance-category chemical}">Chemical</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 45389009}">Tissue stain (substance)</span></p><p><b>description</b>: E-Cadherin (NCH-38), Dako Omnis</p></div>
        </text>
        <status value="active"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/substance-category"/>
            <code value="chemical"/>
            <display value="Chemical"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="45389009"/>
            <display value="Tissue stain (substance)"/>
          </coding>
        </code>
        <description value="E-Cadherin (NCH-38), Dako Omnis"/>
      </Substance>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroscopicGrouper"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroscopicGrouper"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-macroscopic-grouper|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroscopicGrouper"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroscopicGrouper</b></p><a name="IntegratedMacroscopicGrouper"> </a><a name="hcIntegratedMacroscopicGrouper"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-macroscopic-grouper">MII PR Patho Macroscopic Grouper</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>hasMember</b>: </p><ul><li><a href="Observation-IntegratedMacroLength.html">Observation Specimen size.maximum dimension in Breast tumor</a></li><li><a href="Observation-IntegratedMacroWidth.html">Observation Specimen size additional dimension 1 in Breast tumor</a></li><li><a href="Observation-IntegratedMacroDepth.html">Observation Specimen size additional dimension 2 in Breast tumor</a></li><li><a href="Observation-IntegratedMacroWeight.html">Observation Specimen wt Tiss Qn</a></li><li><a href="Observation-IntegratedMacroQuadrant.html">Observation Quadrant Breast</a></li><li><a href="Observation-IntegratedMacroClock.html">Observation Radial position in breast [Angle] in Breast cancer specimen</a></li><li><a href="Observation-IntegratedMacroDistanceNipple.html">Observation Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)</a></li><li><a href="Observation-IntegratedMacroBlockCount.html">Observation Number of paraffin embedded tissue blocks examined from excised specimen (observable entity)</a></li><li><a href="Observation-IntegratedMacroSLN1Size.html">Observation Length of tissue core(s)</a></li><li><a href="Observation-IntegratedMacroSLN2Size.html">Observation Length of tissue core(s)</a></li></ul><p><b>derivedFrom</b>: </p><ul><li><a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li><li><a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></li></ul></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroLength"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroWidth"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroDepth"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroWeight"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroQuadrant"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroClock"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroDistanceNipple"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroBlockCount"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroSLN1Size"/>
        </hasMember>
        <hasMember>🔗 
          <reference value="Observation/IntegratedMacroSLN2Size"/>
        </hasMember>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroLength"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroLength"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroLength"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroLength</b></p><a name="IntegratedMacroLength"> </a><a name="hcIntegratedMacroLength"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44629-4}">ProbeGröße1</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 42 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44629-4"/>
            <display value="Specimen size.maximum dimension in Breast tumor"/>
          </coding>
          <text value="ProbeGröße1"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="42"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroWidth"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroWidth"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroWidth"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroWidth</b></p><a name="IntegratedMacroWidth"> </a><a name="hcIntegratedMacroWidth"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44630-2}">ProbeGröße2</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 35 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44630-2"/>
            <display
                     value="Specimen size additional dimension 1 in Breast tumor"/>
          </coding>
          <text value="ProbeGröße2"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="35"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroDepth"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroDepth"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroDepth"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroDepth</b></p><a name="IntegratedMacroDepth"> </a><a name="hcIntegratedMacroDepth"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44631-0}">ProbeGröße3</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 18 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44631-0"/>
            <display
                     value="Specimen size additional dimension 2 in Breast tumor"/>
          </coding>
          <text value="ProbeGröße3"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="18"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroWeight"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroWeight"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroWeight"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroWeight</b></p><a name="IntegratedMacroWeight"> </a><a name="hcIntegratedMacroWeight"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 29638-4}">Gewicht der Probe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 10 g<span style="background: LightGoldenRodYellow"> (Details: UCUM  codeg = 'g')</span></p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 76752008}">Breast structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="29638-4"/>
            <display value="Specimen wt Tiss Qn"/>
          </coding>
          <text value="Gewicht der Probe"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="10"/>
          <unit value="g"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="g"/>
        </valueQuantity>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="76752008"/>
            <display value="Breast structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroQuadrant"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroQuadrant"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroQuadrant"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroQuadrant</b></p><a name="IntegratedMacroQuadrant"> </a><a name="hcIntegratedMacroQuadrant"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 42799-7}">Quadrantenlokalisaion</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 33564002}">Unterer äußerer Quadrant</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="42799-7"/>
            <display value="Quadrant Breast"/>
          </coding>
          <text value="Quadrantenlokalisaion"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="33564002"/>
            <display
                     value="Structure of lower outer quadrant of breast (body structure)"/>
          </coding>
          <text value="Unterer äußerer Quadrant"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroClock"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroClock"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroClock"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroClock</b></p><a name="IntegratedMacroClock"> </a><a name="hcIntegratedMacroClock"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85332-5}, {http://snomed.info/sct 3980001000004105}">Zifferblattlokalisation</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 5 o'clock<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{clock position} = '{clock position}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85332-5"/>
            <display
                     value="Radial position in breast [Angle] in Breast cancer specimen"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3980001000004105"/>
            <display
                     value="Radial location of primary malignant neoplasm in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Zifferblattlokalisation"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="5"/>
          <unit value="o'clock"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{clock position}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroDistanceNipple"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroDistanceNipple"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroDistanceNipple"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroDistanceNipple</b></p><a name="IntegratedMacroDistanceNipple"> </a><a name="hcIntegratedMacroDistanceNipple"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1240401000}">Abstand von der Mamille</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 50 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1240401000"/>
            <display
                     value="Distance of primary malignant neoplasm of breast to nipple in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Abstand von der Mamille"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="50"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroBlockCount"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroBlockCount"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroBlockCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroBlockCount</b></p><a name="IntegratedMacroBlockCount"> </a><a name="hcIntegratedMacroBlockCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 3100001000004109}">Anzahl Paraffinblöcke</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 6 Blöcke<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{blocks} = '{blocks}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3100001000004109"/>
            <display
                     value="Number of paraffin embedded tissue blocks examined from excised specimen (observable entity)"/>
          </coding>
          <text value="Anzahl Paraffinblöcke"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="6"/>
          <unit value="Blöcke"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{blocks}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroSLN1Size"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroSLN1Size"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroSLN1Size"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroSLN1Size</b></p><a name="IntegratedMacroSLN1Size"> </a><a name="hcIntegratedMacroSLN1Size"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44619-5}">SLN #1 Größe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 12 x 8 x 6 mm, Patentblau-markiert</p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 68171009}">Axillary lymph node structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenBlock01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44619-5"/>
            <display value="Length of tissue core(s)"/>
          </coding>
          <text value="SLN #1 Größe"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString value="12 x 8 x 6 mm, Patentblau-markiert"/>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="68171009"/>
            <display value="Axillary lymph node structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroSLN2Size"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroSLN2Size"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroSLN2Size"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroSLN2Size</b></p><a name="IntegratedMacroSLN2Size"> </a><a name="hcIntegratedMacroSLN2Size"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22634-0}">Pathology report gross observation Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44619-5}">SLN #2 Größe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-06 08:30:00+0100</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 10 x 7 x 5 mm, Patentblau-markiert</p><p><b>bodySite</b>: <span title="Codes:{http://snomed.info/sct 68171009}">Axillary lymph node structure (body structure)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenBlock02.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_2; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue block specimen (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22634-0"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44619-5"/>
            <display value="Length of tissue core(s)"/>
          </coding>
          <text value="SLN #2 Größe"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-06T08:30:00+01:00"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString value="10 x 7 x 5 mm, Patentblau-markiert"/>
        <bodySite>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="68171009"/>
            <display value="Axillary lymph node structure (body structure)"/>
          </coding>
        </bodySite>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenBlock02"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedDiagnosticConclusionGrouper"/>
    <resource>
      <Observation>
        <id value="IntegratedDiagnosticConclusionGrouper"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-diagnostic-conclusion-grouper|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedDiagnosticConclusionGrouper"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedDiagnosticConclusionGrouper</b></p><a name="IntegratedDiagnosticConclusionGrouper"> </a><a name="hcIntegratedDiagnosticConclusionGrouper"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-diagnostic-conclusion-grouper">MII PR Patho Diagnostic Conclusion Grouper</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>hasMember</b>: </p><ul><li><a href="Observation-IntegratedOperativeProcedure.html">Observation Surgery procedure</a></li><li><a href="Observation-IntegratedMaterialType.html">Observation Specimen type</a></li><li><a href="Observation-IntegratedLaterality.html">Observation Specimen laterality (observable entity)</a></li><li><a href="Observation-IntegratedAttachedTissue.html">Observation Body structure 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        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedLaterality"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedLaterality</b></p><a name="IntegratedLaterality"> </a><a name="hcIntegratedLaterality"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 384727002}">Seitenlokalisation der Probe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 7771000}">Links</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="384727002"/>
            <display value="Specimen laterality (observable entity)"/>
          </coding>
          <text value="Seitenlokalisation der Probe"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="7771000"/>
            <display value="Left (qualifier value)"/>
          </coding>
          <text value="Links"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedAttachedTissue"/>
    <resource>
      <Observation>
        <id value="IntegratedAttachedTissue"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedAttachedTissue"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedAttachedTissue</b></p><a name="IntegratedAttachedTissue"> </a><a name="hcIntegratedAttachedTissue"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85298-8}">Material/anhängendes Gewebe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 39937001}">Haut</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Specimen from breast obtained by excision (specimen); note = BET-Exzisionspräparat Mamma links, unterer äußerer Quadrant, 5 Uhr, 50 mm von Mamille. 42 × 35 × 18 mm, 10 g. Haut anhängend, Drahthäkchen in situ. Lamellierung in 8 Scheiben à 5 mm. Schnittfläche: grau-weißlicher Herdbefund zentral in Scheibe III–V, ca. 18 mm.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85298-8"/>
            <display
                     value="Body structure included in specimen [Anatomy] in Specimen"/>
          </coding>
          <text value="Material/anhängendes Gewebe"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="39937001"/>
            <display value="Skin structure (body structure)"/>
          </coding>
          <text value="Haut"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedFocality"/>
    <resource>
      <Observation>
        <id value="IntegratedFocality"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedFocality"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedFocality</b></p><a name="IntegratedFocality"> </a><a name="hcIntegratedFocality"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1157128007}">(Multi)fokalität</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">Unifokal</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1157128007"/>
            <display
                     value="Qualitative distribution of primary malignant neoplasm of breast in excised breast specimen (observable entity)"/>
          </coding>
          <text value="(Multi)fokalität"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="Unifokal"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMaxDiameterInvasive"/>
    <resource>
      <Observation>
        <id value="IntegratedMaxDiameterInvasive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMaxDiameterInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMaxDiameterInvasive</b></p><a name="IntegratedMaxDiameterInvasive"> </a><a name="hcIntegratedMaxDiameterInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44635-1}, {http://snomed.info/sct 200001000004104}">Maximaler Durchmesser invasives Karzinom</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 18 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44635-1"/>
            <display value="Inv comp size max dim BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="200001000004104"/>
            <display
                     value="Greatest length dimension of excised primary malignant neoplasm (observable entity)"/>
          </coding>
          <text value="Maximaler Durchmesser invasives Karzinom"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="18"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMaxOverallDiameter"/>
    <resource>
      <Observation>
        <id value="IntegratedMaxOverallDiameter"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMaxOverallDiameter"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMaxOverallDiameter</b></p><a name="IntegratedMaxOverallDiameter"> </a><a name="hcIntegratedMaxOverallDiameter"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 33728-7}">Maximaler Gesamtdurchmesser der Läsion</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 22 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="33728-7"/>
            <display value="Size.maximum dimension in Tumor"/>
          </coding>
          <text value="Maximaler Gesamtdurchmesser der Läsion"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="22"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedHistologicalType"/>
    <resource>
      <Observation>
        <id value="IntegratedHistologicalType"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedHistologicalType"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedHistologicalType</b></p><a name="IntegratedHistologicalType"> </a><a name="hcIntegratedHistologicalType"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44638-5}, {http://snomed.info/sct 1660001000004100}">Histologischer Tumortyp WHO</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{urn:oid:2.16.840.1.113883.6.43.1 8500/3}">Invasives duktales Karzinom (NST)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44638-5"/>
            <display value="Histo type BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1660001000004100"/>
            <display
                     value="Histologic type of primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Histologischer Tumortyp WHO"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="urn:oid:2.16.840.1.113883.6.43.1"/>
            <code value="8500/3"/>
            <display value="Invasives duktales Karzinom (NST)"/>
          </coding>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMorphologyFreeText"/>
    <resource>
      <Observation>
        <id value="IntegratedMorphologyFreeText"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMorphologyFreeText"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMorphologyFreeText</b></p><a name="IntegratedMorphologyFreeText"> </a><a name="hcIntegratedMorphologyFreeText"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 33731-1}">Morphologie Freitext</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion.</p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="33731-1"/>
            <display value="Histology type in Cancer specimen Narrative"/>
          </coding>
          <text value="Morphologie Freitext"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString
                     value="Invasives Mammakarzinom des NST (kein spezieller Typ), maximal 18 mm messend. Das Karzinom zeigt ein überwiegend trabekuläres und solides Wachstumsmuster mit mäßiger Kern- und Zellpolymorphie. Mitosen sind vereinzelt nachweisbar (4/10 HPF). In der Tumorperipherie zeigt sich ein begleitendes duktales Carcinoma in situ (DCIS) mit intermediärem Kerngrad und überwiegend kribriformem Wachstumsmuster, maximal 8 mm. Fokale Komedo-Nekrosen. Assoziierte Mikroverkalkungen im DCIS-Areal. Alle Resektionsränder tumorfrei. Mindestabstand invasiv: 5 mm (posterior), DCIS: 3 mm. Keine Lymphgefäßinvasion."/>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedNottinghamGrade"/>
    <resource>
      <Observation>
        <id value="IntegratedNottinghamGrade"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedNottinghamGrade"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedNottinghamGrade</b></p><a name="IntegratedNottinghamGrade"> </a><a name="hcIntegratedNottinghamGrade"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44648-4}">Histologischer Tumorgrad (Elston-Ellis-Grad)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 1155703007}">Nottingham Grad 2 (Score 6)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44648-4"/>
            <display
                     value="Histologic grade [Score] in Breast cancer specimen by Nottingham"/>
          </coding>
          <text value="Histologischer Tumorgrad (Elston-Ellis-Grad)"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1155703007"/>
            <display
                     value="G2: Moderately differentiated histologic grade (qualifier value)"/>
          </coding>
          <text value="Nottingham Grad 2 (Score 6)"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedTubuleScore"/>
    <resource>
      <Observation>
        <id value="IntegratedTubuleScore"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedTubuleScore"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedTubuleScore</b></p><a name="IntegratedTubuleScore"> </a><a name="hcIntegratedTubuleScore"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85321-8}">Tubulus Scorewert</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 3 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85321-8"/>
            <display
                     value="Glandular differentiation [Score] in Breast cancer specimen by Nottingham"/>
          </coding>
          <text value="Tubulus Scorewert"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="3"/>
          <unit value="score"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{score}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedNuclearPleomorphism"/>
    <resource>
      <Observation>
        <id value="IntegratedNuclearPleomorphism"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedNuclearPleomorphism"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedNuclearPleomorphism</b></p><a name="IntegratedNuclearPleomorphism"> </a><a name="hcIntegratedNuclearPleomorphism"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44645-0}">Kernpleomorphie Scorewert</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 2 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44645-0"/>
            <display
                     value="Nuclear pleomorphism in Breast tumor by Nottingham"/>
          </coding>
          <text value="Kernpleomorphie Scorewert"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="2"/>
          <unit value="score"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{score}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMitosisCount"/>
    <resource>
      <Observation>
        <id value="IntegratedMitosisCount"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMitosisCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMitosisCount</b></p><a name="IntegratedMitosisCount"> </a><a name="hcIntegratedMitosisCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 406094009}">Mitosezahl</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 4 per 10 HPF<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{HPF} = '{HPF}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="406094009"/>
            <display
                     value="Number of mitoses per 10 high power fields (observable entity)"/>
          </coding>
          <text value="Mitosezahl"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="4"/>
          <unit value="per 10 HPF"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{HPF}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMitoticRateScore"/>
    <resource>
      <Observation>
        <id value="IntegratedMitoticRateScore"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMitoticRateScore"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMitoticRateScore</b></p><a name="IntegratedMitoticRateScore"> </a><a name="hcIntegratedMitoticRateScore"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85300-2}">Mitoserate Scorewert</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85300-2"/>
            <display
                     value="Mitotic rate [Score] in Breast cancer specimen by Nottingham"/>
          </coding>
          <text value="Mitoserate Scorewert"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="1"/>
          <unit value="score"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{score}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedElstonEllisScore"/>
    <resource>
      <Observation>
        <id value="IntegratedElstonEllisScore"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedElstonEllisScore"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedElstonEllisScore</b></p><a name="IntegratedElstonEllisScore"> </a><a name="hcIntegratedElstonEllisScore"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1287461000}">Elston-Ellis-Summenscore</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 6 score<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1287461000"/>
            <display
                     value="Nottingham total score of primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Elston-Ellis-Summenscore"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="6"/>
          <unit value="score"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{score}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedAssociatedDCIS"/>
    <resource>
      <Observation>
        <id value="IntegratedAssociatedDCIS"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedAssociatedDCIS"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedAssociatedDCIS</b></p><a name="IntegratedAssociatedDCIS"> </a><a name="hcIntegratedAssociatedDCIS"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85336-6}">Klassifikation eines assoziiertes DCIS</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 52101004}">DCIS vorhanden</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85336-6"/>
            <display value="DCIS intraduct ext Br ca spec Ql Micro"/>
          </coding>
          <text value="Klassifikation eines assoziiertes DCIS"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="52101004"/>
            <display value="Present (qualifier value)"/>
          </coding>
          <text value="DCIS vorhanden"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedDCISGrade"/>
    <resource>
      <Observation>
        <id value="IntegratedDCISGrade"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedDCISGrade"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedDCISGrade</b></p><a name="IntegratedDCISGrade"> </a><a name="hcIntegratedDCISGrade"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 2890001000004108}">Kerngrading / WHO-Grading nichtinvasiv</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">Intermediär (Grad 2)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2890001000004108"/>
            <display
                     value="Nuclear grade of ductal carcinoma in situ of breast (observable entity)"/>
          </coding>
          <text value="Kerngrading / WHO-Grading nichtinvasiv"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="Intermediär (Grad 2)"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedDCISArchitecture"/>
    <resource>
      <Observation>
        <id value="IntegratedDCISArchitecture"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedDCISArchitecture"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedDCISArchitecture</b></p><a name="IntegratedDCISArchitecture"> </a><a name="hcIntegratedDCISArchitecture"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85302-8}, {http://snomed.info/sct 3400001000004108}">DCIS Architektur</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 443987001}">kribriformer Typ</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85302-8"/>
            <display
                     value="Growth pattern of DCIS [Type] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3400001000004108"/>
            <display
                     value="Architectural pattern of ductal carcinoma in situ in breast (observable entity)"/>
          </coding>
          <text value="DCIS Architektur"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="443987001"/>
            <display value="Cribriform neoplasm pattern (finding)"/>
          </coding>
          <text value="kribriformer Typ"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedDCISNecrosis"/>
    <resource>
      <Observation>
        <id value="IntegratedDCISNecrosis"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedDCISNecrosis"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedDCISNecrosis</b></p><a name="IntegratedDCISNecrosis"> </a><a name="hcIntegratedDCISNecrosis"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85340-8}">Nekrosen</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">Fokal (Komedo-Nekrosen)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85340-8"/>
            <display
                     value="DCIS necrosis [Type] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <text value="Nekrosen"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="Fokal (Komedo-Nekrosen)"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedTumorExtent"/>
    <resource>
      <Observation>
        <id value="IntegratedTumorExtent"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedTumorExtent"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedTumorExtent</b></p><a name="IntegratedTumorExtent"> </a><a name="hcIntegratedTumorExtent"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85322-6}, {http://snomed.info/sct 396645007}, {http://snomed.info/sct 3280001000004106}">Tumorausdehnung</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">Auf Brustdrüse beschränkt</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85322-6"/>
            <display
                     value="Adjacent structure invaded by tumor [Anatomy] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="396645007"/>
            <display
                     value="Status of extension by tumor (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3280001000004106"/>
            <display
                     value="Anatomic location directly invaded by primary malignant neoplasm of breast (observable entity)"/>
          </coding>
          <text value="Tumorausdehnung"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="Auf Brustdrüse beschränkt"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMarginStatusInvasive"/>
    <resource>
      <Observation>
        <id value="IntegratedMarginStatusInvasive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMarginStatusInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMarginStatusInvasive</b></p><a name="IntegratedMarginStatusInvasive"> </a><a name="hcIntegratedMarginStatusInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44669-0}, {http://snomed.info/sct 371488000}, {http://snomed.info/sct 1240395000}">Resektionsrandstatus invasiv</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht befallen (R0)</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideRR-Superior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44669-0"/>
            <display value="Margin involved BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371488000"/>
            <display
                     value="Presence of neoplasm at excised surgical margin (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1240395000"/>
            <display
                     value="Surgical margin involved by primary malignant neoplasm of breast in excised breast specimen (observable entity)"/>
          </coding>
          <text value="Resektionsrandstatus invasiv"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht befallen (R0)"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Superior-HE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedClosestMargin"/>
    <resource>
      <Observation>
        <id value="IntegratedClosestMargin"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedClosestMargin"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedClosestMargin</b></p><a name="IntegratedClosestMargin"> </a><a name="hcIntegratedClosestMargin"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44674-0}, {http://snomed.info/sct 170001000004107}">Richtung des nächsten tumorfreien RR</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">Posterior</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideRR-Superior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44674-0"/>
            <display value="IC uninv marg closest BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="170001000004107"/>
            <display
                     value="Surgical margin closest to malignant neoplasm in excised specimen of breast (observable entity)"/>
          </coding>
          <text value="Richtung des nächsten tumorfreien RR"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="Posterior"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Superior-HE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMinDistanceInvasive"/>
    <resource>
      <Observation>
        <id value="IntegratedMinDistanceInvasive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMinDistanceInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMinDistanceInvasive</b></p><a name="IntegratedMinDistanceInvasive"> </a><a name="hcIntegratedMinDistanceInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44672-4}, {http://snomed.info/sct 373120008}">Mindestabstand des invasiven Tumor zum nächstgelegenen Resektionsrand</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 5 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideRR-Superior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44672-4"/>
            <display value="IC uninv marg dist closest BT"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="373120008"/>
            <display
                     value="Distance of invasive carcinoma of breast from closest surgical margin in excised breast specimen (observable entity)"/>
          </coding>
          <text
                value="Mindestabstand des invasiven Tumor zum nächstgelegenen Resektionsrand"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="5"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Superior-HE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMarginStatusNonInvasive"/>
    <resource>
      <Observation>
        <id value="IntegratedMarginStatusNonInvasive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMarginStatusNonInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMarginStatusNonInvasive</b></p><a name="IntegratedMarginStatusNonInvasive"> </a><a name="hcIntegratedMarginStatusNonInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85334-1}, {http://snomed.info/sct 384705006}">Resektionsrandstatus nichtinvasiv</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht befallen</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideRR-Superior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85334-1"/>
            <display
                     value="Surgical margin DCIS involvement [Presence] in Breast cancer specimen by Light microscopy"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="384705006"/>
            <display
                     value="Presence of ductal carcinoma in situ at surgical margin in excised specimen of breast (observable entity)"/>
          </coding>
          <text value="Resektionsrandstatus nichtinvasiv"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht befallen"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Superior-HE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMinDistanceNonInvasive"/>
    <resource>
      <Observation>
        <id value="IntegratedMinDistanceNonInvasive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMinDistanceNonInvasive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMinDistanceNonInvasive</b></p><a name="IntegratedMinDistanceNonInvasive"> </a><a name="hcIntegratedMinDistanceNonInvasive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 44673-2}">Mindestabstand vom RR zum nichtinvasiven Tumor</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 3 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideRR-Superior-HE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_3_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="44673-2"/>
            <display value="DCIS.uninv marg dist.closest BT"/>
          </coding>
          <text value="Mindestabstand vom RR zum nichtinvasiven Tumor"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="3"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideRR-Superior-HE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/IntegratedLVI"/>
    <resource>
      <Observation>
        <id value="IntegratedLVI"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedLVI"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedLVI</b></p><a name="IntegratedLVI"> </a><a name="hcIntegratedLVI"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 59544-7}, {http://snomed.info/sct 371512006}">Peritumorale Gefäßinvasion</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht nachgewiesen</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="59544-7"/>
            <display value="Lymph-vascular invasion Ca spec"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371512006"/>
            <display
                     value="Presence of direct invasion by primary malignant neoplasm to lymphatic vessel and/or small blood vessel (observable entity)"/>
          </coding>
          <text value="Peritumorale Gefäßinvasion"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht nachgewiesen"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMicrocalcification"/>
    <resource>
      <Observation>
        <id value="IntegratedMicrocalcification"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMicrocalcification"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMicrocalcification</b></p><a name="IntegratedMicrocalcification"> </a><a name="hcIntegratedMicrocalcification"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1240404008}">Presence of microcalcification in excised breast specimen (observable entity)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA27826-9}">Microcalcifications present in DCIS</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1240404008"/>
            <display
                     value="Presence of microcalcification in excised breast specimen (observable entity)"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://loinc.org"/>
            <code value="LA27826-9"/>
            <display value="Microcalcifications present in DCIS"/>
          </coding>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedERStatus"/>
    <resource>
      <Observation>
        <id value="IntegratedERStatus"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedERStatus"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedERStatus</b></p><a name="IntegratedERStatus"> </a><a name="hcIntegratedERStatus"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 16112-5}, {http://snomed.info/sct 1234806008}">Hormonrezeptorstatus Östrogen</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 52101004}">Positiv</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideER01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3467}">ESR1</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="16112-5"/>
            <display value="Estrogen receptor [Interpretation] in Tissue"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Hormonrezeptorstatus Östrogen"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="52101004"/>
            <display value="Present (qualifier value)"/>
          </coding>
          <text value="Positiv"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideER01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3467"/>
              <display value="ESR1"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedERPercentage"/>
    <resource>
      <Observation>
        <id value="IntegratedERPercentage"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedERPercentage"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedERPercentage</b></p><a name="IntegratedERPercentage"> </a><a name="hcIntegratedERPercentage"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85329-1}, {http://snomed.info/sct 1234804006}, {http://snomed.info/sct 1234806008}">PP ER</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 90 %<span style="background: LightGoldenRodYellow"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideER01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3467}">ESR1</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
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        <status value="final"/>
        <category>
          <coding>
            <system
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            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85329-1"/>
            <display
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          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234804006"/>
            <display
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          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
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          </coding>
          <text value="PP ER"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="90"/>
          <unit value="%"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="%"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideER01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
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        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
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          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3467"/>
              <display value="ESR1"/>
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          </valueCodeableConcept>
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  <entry>
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    <resource>
      <Observation>
        <id value="IntegratedERIntensity"/>
        <meta>
          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedERIntensity"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedERIntensity</b></p><a name="IntegratedERIntensity"> </a><a name="hcIntegratedERIntensity"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85310-1}, {http://snomed.info/sct 1236874005}, {http://snomed.info/sct 1234806008}">Färbeintensität ER</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 24484000}">Stark</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideER01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_ER_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3467}">ESR1</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85310-1"/>
            <display
                     value="Estrogen receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1236874005"/>
            <display
                     value="Intensity of stain of estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Färbeintensität ER"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="24484000"/>
            <display value="Severe (severity modifier) (qualifier value)"/>
          </coding>
          <text value="Stark"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideER01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3467"/>
              <display value="ESR1"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedPRStatus"/>
    <resource>
      <Observation>
        <id value="IntegratedPRStatus"/>
        <meta>
          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedPRStatus"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedPRStatus</b></p><a name="IntegratedPRStatus"> </a><a name="hcIntegratedPRStatus"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 16113-3}, {http://snomed.info/sct 1234806008}">Hormonrezeptorstatus Progesteron</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 52101004}">Positiv</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlidePR01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:8910}">PGR</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="16113-3"/>
            <display
                     value="Progesterone receptor [Interpretation] in Tissue"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Hormonrezeptorstatus Progesteron"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="52101004"/>
            <display value="Present (qualifier value)"/>
          </coding>
          <text value="Positiv"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlidePR01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:8910"/>
              <display value="PGR"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedPRPercentage"/>
    <resource>
      <Observation>
        <id value="IntegratedPRPercentage"/>
        <meta>
          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedPRPercentage"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedPRPercentage</b></p><a name="IntegratedPRPercentage"> </a><a name="hcIntegratedPRPercentage"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85325-9}, {http://snomed.info/sct 1234803000}, {http://snomed.info/sct 1234806008}">PP PR</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 60 %<span style="background: LightGoldenRodYellow"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlidePR01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:8910}">PGR</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85325-9"/>
            <display
                     value="Cells.progesterone receptor/cells in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234803000"/>
            <display
                     value="Percent of cells with progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="PP PR"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="60"/>
          <unit value="%"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="%"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlidePR01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:8910"/>
              <display value="PGR"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedPRIntensity"/>
    <resource>
      <Observation>
        <id value="IntegratedPRIntensity"/>
        <meta>
          <profile
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        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedPRIntensity"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedPRIntensity</b></p><a name="IntegratedPRIntensity"> </a><a name="hcIntegratedPRIntensity"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85331-7}, {http://snomed.info/sct 1237278006}, {http://snomed.info/sct 1234806008}">Färbeintensität PR</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 6736007}">Mäßig</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlidePR01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_PR_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:8910}">PGR</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85331-7"/>
            <display
                     value="Progesterone receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1237278006"/>
            <display
                     value="Intensity of stain of progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Färbeintensität PR"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="6736007"/>
            <display value="Moderate (severity modifier) (qualifier value)"/>
          </coding>
          <text value="Mäßig"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlidePR01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:8910"/>
              <display value="PGR"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedHER2IHC"/>
    <resource>
      <Observation>
        <id value="IntegratedHER2IHC"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedHER2IHC"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedHER2IHC</b></p><a name="IntegratedHER2IHC"> </a><a name="hcIntegratedHER2IHC"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85319-2}, {http://snomed.info/sct 3550001000004108}, {http://snomed.info/sct 1234806008}">Her2 Score</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:">1+</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHER2IHC01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3430}">ERBB2</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85319-2"/>
            <display
                     value="HER2 [Presence] in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="3550001000004108"/>
            <display
                     value="Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Her2 Score"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <text value="1+"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHER2IHC01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3430"/>
              <display value="ERBB2"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedHER2ISH"/>
    <resource>
      <Observation>
        <id value="IntegratedHER2ISH"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedHER2ISH"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedHER2ISH</b></p><a name="IntegratedHER2ISH"> </a><a name="hcIntegratedHER2ISH"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85318-4}">Her2 Amplifikation</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht amplifiziert</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHER2IHC01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3430}">ERBB2</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85318-4"/>
            <display
                     value="ERBB2 gene duplication [Presence] in Breast cancer specimen by FISH"/>
          </coding>
          <text value="Her2 Amplifikation"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht amplifiziert"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHER2IHC01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3430"/>
              <display value="ERBB2"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedHER2Overall"/>
    <resource>
      <Observation>
        <id value="IntegratedHER2Overall"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedHER2Overall"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedHER2Overall</b></p><a name="IntegratedHER2Overall"> </a><a name="hcIntegratedHER2Overall"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 48676-1}">Her2neuStatus</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Negativ</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideHER2IHC01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_HER2_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:3430}">ERBB2</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="48676-1"/>
            <display value="HER2 [Interpretation] in Tissue"/>
          </coding>
          <text value="Her2neuStatus"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Negativ"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideHER2IHC01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:3430"/>
              <display value="ERBB2"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/IntegratedKi67"/>
    <resource>
      <Observation>
        <id value="IntegratedKi67"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedKi67"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedKi67</b></p><a name="IntegratedKi67"> </a><a name="hcIntegratedKi67"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85330-9}, {http://snomed.info/sct 1237281001}, {http://snomed.info/sct 1234806008}">Ki67-Index</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 15 %<span style="background: LightGoldenRodYellow"> (Details: UCUM  code% = '%')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedBETSlideKi67-01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_A_1_1_Ki67_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></td><td><span title="Codes:{http://www.genenames.org/geneId HGNC:7107}">MKI67</span></td></tr></table></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85330-9"/>
            <display
                     value="Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1237281001"/>
            <display
                     value="Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of breast by immunohistochemistry (observable entity)"/>
          </coding>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1234806008"/>
            <display
                     value="Observation using immunohistochemistry (observable entity)"/>
          </coding>
          <text value="Ki67-Index"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="15"/>
          <unit value="%"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="%"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedBETSlideKi67-01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
        <component>
          <code>
            <coding>
              <system value="http://loinc.org"/>
              <code value="48018-6"/>
              <display value="Gene studied [ID]"/>
            </coding>
          </code>
          <valueCodeableConcept>
            <coding>
              <system value="http://www.genenames.org/geneId"/>
              <code value="HGNC:7107"/>
              <display value="MKI67"/>
            </coding>
          </valueCodeableConcept>
        </component>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/IntegratedPT"/>
    <resource>
      <Observation>
        <id value="IntegratedPT"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedPT"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedPT</b></p><a name="IntegratedPT"> </a><a name="hcIntegratedPT"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-t-kategorie">MII PR Onkologie TNM T-Kategorie</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 384625004}">pT category (observable entity)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>value</b>: <span title="Codes:{https://www.uicc.org/resources/tnm T1}">T1</span></p><p><b>method</b>: <span title="Codes:{https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version 8}">8. Auflage</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix">
            <valueCodeableConcept>
              <coding>
                <system value="https://www.uicc.org/resources/tnm"/>
                <code value="p"/>
                <display value="p"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="384625004"/>
            <display value="pT category (observable entity)"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <valueCodeableConcept>
          <coding>
            <system value="https://www.uicc.org/resources/tnm"/>
            <code value="T1"/>
            <display value="T1"/>
          </coding>
        </valueCodeableConcept>
        <method>
          <coding>
            <system
                    value="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version"/>
            <code value="8"/>
            <display value="8. Auflage"/>
          </coding>
        </method>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedBETComment"/>
    <resource>
      <Observation>
        <id value="IntegratedBETComment"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedBETComment"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedBETComment</b></p><a name="IntegratedBETComment"> </a><a name="hcIntegratedBETComment"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22638-1}">Kommentar</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRBreastResection.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_Mamma_GH' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22638-1"/>
            <display
                     value="Pathology report comments [Interpretation] Narrative"/>
          </coding>
          <text value="Kommentar"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString
                     value="Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung."/>
        <derivedFrom>🔗 
          <reference
                     value="QuestionnaireResponse/IntegratedQRBreastResection"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedLymphNodeProcedure"/>
    <resource>
      <Observation>
        <id value="IntegratedLymphNodeProcedure"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedLymphNodeProcedure"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedLymphNodeProcedure</b></p><a name="IntegratedLymphNodeProcedure"> </a><a name="hcIntegratedLymphNodeProcedure"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 21877-6}">LK OP Prozedur</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 396487001}">Sentinel-Lymphknoten-Biopsie</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="21877-6"/>
            <display
                     value="Surgery procedure for regional nodes at facility.YYY Cancer"/>
          </coding>
          <text value="LK OP Prozedur"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="396487001"/>
            <display value="Sentinel lymph node biopsy (procedure)"/>
          </coding>
          <text value="Sentinel-Lymphknoten-Biopsie"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedLymphNodeLaterality"/>
    <resource>
      <Observation>
        <id value="IntegratedLymphNodeLaterality"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedLymphNodeLaterality"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedLymphNodeLaterality</b></p><a name="IntegratedLymphNodeLaterality"> </a><a name="hcIntegratedLymphNodeLaterality"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 20228-3}">Seitenangabe</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 7771000}">Links</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="20228-3"/>
            <display value="Anatomic part Laterality"/>
          </coding>
          <text value="Seitenangabe"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="7771000"/>
            <display value="Left (qualifier value)"/>
          </coding>
          <text value="Links"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedNonSLNExamined"/>
    <resource>
      <Observation>
        <id value="IntegratedNonSLNExamined"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedNonSLNExamined"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedNonSLNExamined</b></p><a name="IntegratedNonSLNExamined"> </a><a name="hcIntegratedNonSLNExamined"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 21894-1}">Anzahl untersuchter Non-SLN-axillärer LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="21894-1"/>
            <display value="Regional lymph nodes examined [#] Specimen"/>
          </coding>
          <text value="Anzahl untersuchter Non-SLN-axillärer LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="0"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedNonSLNPositive"/>
    <resource>
      <Observation>
        <id value="IntegratedNonSLNPositive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedNonSLNPositive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedNonSLNPositive</b></p><a name="IntegratedNonSLNPositive"> </a><a name="hcIntegratedNonSLNPositive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 21893-3}">Anzahl befallener Non-SLN-axillärer LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="21893-3"/>
            <display value="Regional lymph nodes positive [#] Specimen"/>
          </coding>
          <text value="Anzahl befallener Non-SLN-axillärer LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="0"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedSLNExamined"/>
    <resource>
      <Observation>
        <id value="IntegratedSLNExamined"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedSLNExamined"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedSLNExamined</b></p><a name="IntegratedSLNExamined"> </a><a name="hcIntegratedSLNExamined"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85347-3}">Anzahl untersuchter Sentinel-LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 2 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85347-3"/>
            <display
                     value="Sentinel lymph nodes examined [#] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Anzahl untersuchter Sentinel-LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="2"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedSLNPositive"/>
    <resource>
      <Observation>
        <id value="IntegratedSLNPositive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedSLNPositive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedSLNPositive</b></p><a name="IntegratedSLNPositive"> </a><a name="hcIntegratedSLNPositive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 1264491009}">Anzahl befallener Sentinel-LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="1264491009"/>
            <display
                     value="Number of sentinel lymph nodes containing metastatic neoplasm in excised specimen (observable entity)"/>
          </coding>
          <text value="Anzahl befallener Sentinel-LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="1"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedTotalExamined"/>
    <resource>
      <Observation>
        <id value="IntegratedTotalExamined"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedTotalExamined"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedTotalExamined</b></p><a name="IntegratedTotalExamined"> </a><a name="hcIntegratedTotalExamined"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 92833-3}">Gesamtzahl untersuchter Lymphknoten</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 2 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="92833-3"/>
            <display
                     value="Lymph nodes examined [#] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Gesamtzahl untersuchter Lymphknoten"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="2"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedTotalPositive"/>
    <resource>
      <Observation>
        <id value="IntegratedTotalPositive"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedTotalPositive"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedTotalPositive</b></p><a name="IntegratedTotalPositive"> </a><a name="hcIntegratedTotalPositive"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 92831-7}">Gesamtzahl befallener Lymphknoten</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="92831-7"/>
            <display
                     value="Lymph nodes with metastasis [#] in Cancer specimen"/>
          </coding>
          <text value="Gesamtzahl befallener Lymphknoten"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="1"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMacroMetCount"/>
    <resource>
      <Observation>
        <id value="IntegratedMacroMetCount"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMacroMetCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMacroMetCount</b></p><a name="IntegratedMacroMetCount"> </a><a name="hcIntegratedMacroMetCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85343-2}">Gesamtzahl makrometastatisch befallener LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85343-2"/>
            <display
                     value="Lymph nodes with macrometastases [#] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Gesamtzahl makrometastatisch befallener LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="0"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedMicroMetCount"/>
    <resource>
      <Observation>
        <id value="IntegratedMicroMetCount"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedMicroMetCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedMicroMetCount</b></p><a name="IntegratedMicroMetCount"> </a><a name="hcIntegratedMicroMetCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85344-0}">Gesamtzahl mikrometastatisch befallener LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85344-0"/>
            <display
                     value="Lymph nodes with micrometastases [#] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Gesamtzahl mikrometastatisch befallener LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="1"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedITCCount"/>
    <resource>
      <Observation>
        <id value="IntegratedITCCount"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedITCCount"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedITCCount</b></p><a name="IntegratedITCCount"> </a><a name="hcIntegratedITCCount"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85352-3}">Gesamtzahl ausschließlich ITC-befallener LK</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 0 {count}<span style="background: LightGoldenRodYellow"> (Details: UCUM  code{count} = '{count}')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSpecimenPart.html">Specimen: identifier = Placer Identifier,Filler Identifier; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Lymph node specimen (specimen); note = Sentinel-Lymphknoten-Exzisat linke Axilla, 2 SLN identifiziert (Patentblau-markiert). SLN #1: 12 x 8 x 6 mm, SLN #2: 10 x 7 x 5 mm. Beide halbiert und vollständig eingebettet.</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85352-3"/>
            <display
                     value="Lymph nodes with isolated tumor cells [#] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Gesamtzahl ausschließlich ITC-befallener LK"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="0"/>
          <unit value="{count}"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="{count}"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSpecimenPart"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedLargestMetSize"/>
    <resource>
      <Observation>
        <id value="IntegratedLargestMetSize"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedLargestMetSize"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedLargestMetSize</b></p><a name="IntegratedLargestMetSize"> </a><a name="hcIntegratedLargestMetSize"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85351-5}">Ausdehnung der größten metastatischen Infiltration</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: 1.2 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85351-5"/>
            <display
                     value="Lymph node metastatic deposit.max dimension [Length] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Ausdehnung der größten metastatischen Infiltration"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueQuantity>
          <value value="1.2"/>
          <unit value="mm"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="mm"/>
        </valueQuantity>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedExtranodalExtension"/>
    <resource>
      <Observation>
        <id value="IntegratedExtranodalExtension"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedExtranodalExtension"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedExtranodalExtension</b></p><a name="IntegratedExtranodalExtension"> </a><a name="hcIntegratedExtranodalExtension"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 85350-7}">Extranodale Infiltration durch LK-Metastase</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: <span title="Codes:{http://snomed.info/sct 2667000}">Nicht vorhanden</span></p><p><b>specimen</b>: <a href="Specimen-IntegratedSLNSlideHE01.html">Specimen: identifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300_B_1_1_HE_01; accessionIdentifier = https://pathologie.example-hospital.de/fhir/fn/befundbericht#E_25_300; status = available; type = Tissue section (specimen)</a></p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="85350-7"/>
            <display
                     value="Extranodal extension of carcinoma [Presence] in Cancer specimen by Light microscopy"/>
          </coding>
          <text value="Extranodale Infiltration durch LK-Metastase"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueCodeableConcept>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="2667000"/>
            <display value="Absent (qualifier value)"/>
          </coding>
          <text value="Nicht vorhanden"/>
        </valueCodeableConcept>
        <specimen>🔗 
          <reference value="Specimen/IntegratedSLNSlideHE01"/>
        </specimen>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl value="http://breastcancerspec.org/Observation/IntegratedPN"/>
    <resource>
      <Observation>
        <id value="IntegratedPN"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedPN"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedPN</b></p><a name="IntegratedPN"> </a><a name="hcIntegratedPN"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-tnm-n-kategorie">MII PR Onkologie TNM N-Kategorie</a> version: 2026.0.0</p></div><p><b>status</b>: Final</p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 371494008}">pN category (observable entity)</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>value</b>: <span title="Codes:{https://www.uicc.org/resources/tnm N1mi(sn)}">N1mi(sn)</span></p><p><b>method</b>: <span title="Codes:{https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version 8}">8. Auflage</span></p></div>
        </text>
        <status value="final"/>
        <code>
          <extension
                     url="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-tnm-cp-praefix">
            <valueCodeableConcept>
              <coding>
                <system value="https://www.uicc.org/resources/tnm"/>
                <code value="p"/>
                <display value="p"/>
              </coding>
            </valueCodeableConcept>
          </extension>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="371494008"/>
            <display value="pN category (observable entity)"/>
          </coding>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <valueCodeableConcept>
          <coding>
            <system value="https://www.uicc.org/resources/tnm"/>
            <code value="N1mi(sn)"/>
            <display value="N1mi(sn)"/>
          </coding>
        </valueCodeableConcept>
        <method>
          <coding>
            <system
                    value="https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-tnm-version"/>
            <code value="8"/>
            <display value="8. Auflage"/>
          </coding>
        </method>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/Observation/IntegratedSLNComment"/>
    <resource>
      <Observation>
        <id value="IntegratedSLNComment"/>
        <meta>
          <profile
                   value="https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding|2026.0.0"/>
        </meta>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_IntegratedSLNComment"> </a><p class="res-header-id"><b>Generated Narrative: Observation IntegratedSLNComment</b></p><a name="IntegratedSLNComment"> </a><a name="hcIntegratedSLNComment"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="https://simplifier.net/resolve?scope=de.medizininformatikinitiative.kerndatensatz.patho@2026.0.0&amp;canonical=https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-finding">MII PR Patho Finding</a> version: 2026.0.0</p></div><p><b>basedOn</b>: <a href="ServiceRequest-IntegratedReportRequest.html">ServiceRequest Pathology synoptic report</a></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>, <span title="Codes:{http://loinc.org 22637-3}">Pathology report final diagnosis Narrative</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 22638-1}">Kommentar</span></p><p><b>subject</b>: <a href="Patient-Patient4.html">Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)</a></p><p><b>effective</b>: 2025-02-10</p><p><b>performer</b>: <a href="Practitioner-PathologistPractitioner.html">Practitioner Elisabeth Hoffmann </a></p><p><b>value</b>: In SLN #1 Nachweis einer Mikrometastase (1,2 mm) im Randsinus. SLN #2 tumorfrei in allen Schnittstufen. Keine extranodale Infiltration. Klassifikation: pN1mi(sn). Empfehlung: Besprechung in Tumorkonferenz bzgl. weiterer axillärer Therapie.</p><p><b>derivedFrom</b>: <a href="QuestionnaireResponse-IntegratedQRLymphNode.html">Response to Questionnaire 'http://breastcancerspec.org/Questionnaire/OP_LN-Mamma' about '-&gt;Sabine Becker  Female, DoB: 1971-03-15 ( http://example.hospital.de/patient-ids#PAT-2025-105)'</a></p></div>
        </text>
        <basedOn>🔗 
          <reference value="ServiceRequest/IntegratedReportRequest"/>
        </basedOn>
        <status value="final"/>
        <category>
          <coding>
            <system
                    value="http://terminology.hl7.org/CodeSystem/observation-category"/>
            <code value="laboratory"/>
          </coding>
        </category>
        <category>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22637-3"/>
          </coding>
        </category>
        <code>
          <coding>
            <system value="http://loinc.org"/>
            <code value="22638-1"/>
            <display
                     value="Pathology report comments [Interpretation] Narrative"/>
          </coding>
          <text value="Kommentar"/>
        </code>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <effectiveDateTime value="2025-02-10"/>
        <performer>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </performer>
        <valueString
                     value="In SLN #1 Nachweis einer Mikrometastase (1,2 mm) im Randsinus. SLN #2 tumorfrei in allen Schnittstufen. Keine extranodale Infiltration. Klassifikation: pN1mi(sn). Empfehlung: Besprechung in Tumorkonferenz bzgl. weiterer axillärer Therapie."/>
        <derivedFrom>🔗 
          <reference value="QuestionnaireResponse/IntegratedQRLymphNode"/>
        </derivedFrom>
      </Observation>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/QuestionnaireResponse/IntegratedQRBreastResection"/>
    <resource>
      <QuestionnaireResponse>
        <id value="IntegratedQRBreastResection"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="QuestionnaireResponse_IntegratedQRBreastResection"> </a><p class="res-header-id"><b>Generated Narrative: QuestionnaireResponse IntegratedQRBreastResection</b></p><a name="IntegratedQRBreastResection"> </a><a name="hcIntegratedQRBreastResection"> </a><table border="1" cellpadding="0" cellspacing="0" style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 2px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="The linkID for the item">LinkID</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Text for the item">Text</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Minimum and Maximum # of times the item can appear in the instance">Definition</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="The type of the item">Answer</a><span style="float: right"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_q_root.gif" alt="." style="background-color: white; background-color: inherit" title="QuestionnaireResponseRoot" class="hierarchy"/> IntegratedQRBreastResection</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Questionnaire:http://breastcancerspec.org/Questionnaire/OP_Mamma_GH</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.root</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">BET Mamma</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> bet.clinical</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Klinische Angaben</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11951</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Proben limitiert auswertbar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/373067005">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11912</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Präsentationsmodus</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Frisch</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11147</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Klinische Befunde / Anlass</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Z.n. Stanzbiopsie mit Nachweis eines invasiven Mammakarzinoms NST, G2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11923</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Brustkrebsvorgeschichte</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ersterkrankung</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11952</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Vorchirurgische Therapie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/373067005">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11918</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Bildgebungsmodalität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mammografie, Ultraschall</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11953</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Radiologische Ausdehnung</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>15 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10160</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Befundmarkierung</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Drahthäkchen</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10130</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Präparateradiographie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ja, beigelegt</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11954</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Genetische Prädisposition</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nicht bekannt</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.macro</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Makroskopie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10900</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Probengröße 1 (Länge)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>65 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10910</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Probengröße 2 (Breite)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>45 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10920</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Probengröße 3 (Tiefe)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>30 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10890</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gewicht</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>55 g<span style="background: LightGoldenRodYellow"> (Details: UCUM  codeg = 'g')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10030</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Quadrant</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/33564002">SNOMED CT: 33564002</a> (Structure of lower outer quadrant of breast (body structure))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10040</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Zifferblattlokalisation</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">5 Uhr</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10070</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Abstand Mamille</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>50 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.general</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Allgemeine Befunde</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11130</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nichtinvasive Läsion</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11270</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Karzinom</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11919</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Operatives Verfahren</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/237371007">SNOMED CT: 237371007</a> (Wide local excision of breast lesion (procedure))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10140</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Materialart</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Exzisionspräparat</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10800</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Seitenlokalisation</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/7771000">SNOMED CT: 7771000</a> (Left (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11040</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Anhängendes Gewebe</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Haut</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11440</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Fokalität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Unifokal</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.invasive</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Karzinom</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11400</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Max Durchmesser invasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>18 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11420</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Max Gesamtdurchmesser</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>22 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11280</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Histologischer Tumortyp</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>unknown: 8500/3 (Invasives duktales Karzinom (NST))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11290</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Morphologie Freitext</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Mammakarzinom des NST, überwiegend trabekuläres und solides Wachstumsmuster</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11330</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nottingham-Grad</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">G2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11340</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Tubulus-Score</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">3</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11350</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kernpleomorphie-Score</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11925</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mitosezahl</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">4/10 HPF</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11360</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mitoserate-Score</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11390</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Elston-Ellis-Summenscore</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">6</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11300</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Assoziiertes DCIS</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 149</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">DCIS Kerngrading</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Intermediär (Grad 2)</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 150</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">DCIS Architektur</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kribriform</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 151</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">DCIS Nekrosen</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Fokal (Komedo-Nekrosen)</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11926</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Tumorausdehnung</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Auf Brustdrüse beschränkt</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.margins</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Resektionsränder</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11470</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">RR-Status invasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11490</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nächster tumorfreier RR</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Posterior</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11480</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mindestabstand invasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>5 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11968</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">RR-Status nichtinvasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11970</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mindestabstand nichtinvasiv</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>3 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.additional</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Weitere Befunde</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11430</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">LVI</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 10880</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mikrokalzifikationen</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">In DCIS assoziiert</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> bet.biomarkers</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Biomarker</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11750</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ER-Status</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11720</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ER Prozent</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">90</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11730</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">ER Färbeintensität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Stark</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11790</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">PR-Status</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/52101004">SNOMED CT: 52101004</a> (Present (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11760</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">PR Prozent</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">60</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11770</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">PR Färbeintensität</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mäßig</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11810</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HER2-Score (IHC)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1+</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11820</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HER2-Amplifikation (ISH)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Nicht amplifiziert</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11830</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">HER2-Gesamtstatus</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Negativ</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11840</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ki-67-Index</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">15</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.tnm</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">TNM</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 169</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">pT-Kategorie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">pT1c</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck001.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> bet.comment</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kommentar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0000.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11900</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Kommentar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung.</td></tr>
<tr><td colspan="4" class="hierarchy"><br/><a href="https://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
        </text>
        <questionnaire
                       value="http://breastcancerspec.org/Questionnaire/OP_Mamma_GH"/>
        <status value="completed"/>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <authored value="2025-02-10T14:30:00+01:00"/>
        <author>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </author>
        <item>
          <linkId value="bet.root"/>
          <text value="BET Mamma"/>
          <item>
            <linkId value="bet.clinical"/>
            <text value="Klinische Angaben"/>
            <item>
              <linkId value="11951"/>
              <text value="Proben limitiert auswertbar"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="373067005"/>
                  <display value="No (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11912"/>
              <text value="Präsentationsmodus"/>
              <answer>
                <valueString value="Frisch"/>
              </answer>
            </item>
            <item>
              <linkId value="11147"/>
              <text value="Klinische Befunde / Anlass"/>
              <answer>
                <valueString
                             value="Z.n. Stanzbiopsie mit Nachweis eines invasiven Mammakarzinoms NST, G2"/>
              </answer>
            </item>
            <item>
              <linkId value="11923"/>
              <text value="Brustkrebsvorgeschichte"/>
              <answer>
                <valueString value="Ersterkrankung"/>
              </answer>
            </item>
            <item>
              <linkId value="11952"/>
              <text value="Vorchirurgische Therapie"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="373067005"/>
                  <display value="No (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11918"/>
              <text value="Bildgebungsmodalität"/>
              <answer>
                <valueString value="Mammografie, Ultraschall"/>
              </answer>
            </item>
            <item>
              <linkId value="11953"/>
              <text value="Radiologische Ausdehnung"/>
              <answer>
                <valueQuantity>
                  <value value="15"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10160"/>
              <text value="Befundmarkierung"/>
              <answer>
                <valueString value="Drahthäkchen"/>
              </answer>
            </item>
            <item>
              <linkId value="10130"/>
              <text value="Präparateradiographie"/>
              <answer>
                <valueString value="Ja, beigelegt"/>
              </answer>
            </item>
            <item>
              <linkId value="11954"/>
              <text value="Genetische Prädisposition"/>
              <answer>
                <valueString value="Nicht bekannt"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.macro"/>
            <text value="Makroskopie"/>
            <item>
              <linkId value="10900"/>
              <text value="Probengröße 1 (Länge)"/>
              <answer>
                <valueQuantity>
                  <value value="65"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10910"/>
              <text value="Probengröße 2 (Breite)"/>
              <answer>
                <valueQuantity>
                  <value value="45"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10920"/>
              <text value="Probengröße 3 (Tiefe)"/>
              <answer>
                <valueQuantity>
                  <value value="30"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10890"/>
              <text value="Gewicht"/>
              <answer>
                <valueQuantity>
                  <value value="55"/>
                  <unit value="g"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="g"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="10030"/>
              <text value="Quadrant"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="33564002"/>
                  <display
                           value="Structure of lower outer quadrant of breast (body structure)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="10040"/>
              <text value="Zifferblattlokalisation"/>
              <answer>
                <valueString value="5 Uhr"/>
              </answer>
            </item>
            <item>
              <linkId value="10070"/>
              <text value="Abstand Mamille"/>
              <answer>
                <valueQuantity>
                  <value value="50"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.general"/>
            <text value="Allgemeine Befunde"/>
            <item>
              <linkId value="11130"/>
              <text value="Nichtinvasive Läsion"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11270"/>
              <text value="Invasives Karzinom"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11919"/>
              <text value="Operatives Verfahren"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="237371007"/>
                  <display
                           value="Wide local excision of breast lesion (procedure)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="10140"/>
              <text value="Materialart"/>
              <answer>
                <valueString value="Exzisionspräparat"/>
              </answer>
            </item>
            <item>
              <linkId value="10800"/>
              <text value="Seitenlokalisation"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="7771000"/>
                  <display value="Left (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11040"/>
              <text value="Anhängendes Gewebe"/>
              <answer>
                <valueString value="Haut"/>
              </answer>
            </item>
            <item>
              <linkId value="11440"/>
              <text value="Fokalität"/>
              <answer>
                <valueString value="Unifokal"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.invasive"/>
            <text value="Invasives Karzinom"/>
            <item>
              <linkId value="11400"/>
              <text value="Max Durchmesser invasiv"/>
              <answer>
                <valueQuantity>
                  <value value="18"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11420"/>
              <text value="Max Gesamtdurchmesser"/>
              <answer>
                <valueQuantity>
                  <value value="22"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11280"/>
              <text value="Histologischer Tumortyp"/>
              <answer>
                <valueCoding>
                  <system value="urn:oid:2.16.840.1.113883.6.43.1"/>
                  <code value="8500/3"/>
                  <display value="Invasives duktales Karzinom (NST)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11290"/>
              <text value="Morphologie Freitext"/>
              <answer>
                <valueString
                             value="Invasives Mammakarzinom des NST, überwiegend trabekuläres und solides Wachstumsmuster"/>
              </answer>
            </item>
            <item>
              <linkId value="11330"/>
              <text value="Nottingham-Grad"/>
              <answer>
                <valueString value="G2"/>
              </answer>
            </item>
            <item>
              <linkId value="11340"/>
              <text value="Tubulus-Score"/>
              <answer>
                <valueInteger value="3"/>
              </answer>
            </item>
            <item>
              <linkId value="11350"/>
              <text value="Kernpleomorphie-Score"/>
              <answer>
                <valueInteger value="2"/>
              </answer>
            </item>
            <item>
              <linkId value="11925"/>
              <text value="Mitosezahl"/>
              <answer>
                <valueString value="4/10 HPF"/>
              </answer>
            </item>
            <item>
              <linkId value="11360"/>
              <text value="Mitoserate-Score"/>
              <answer>
                <valueInteger value="1"/>
              </answer>
            </item>
            <item>
              <linkId value="11390"/>
              <text value="Elston-Ellis-Summenscore"/>
              <answer>
                <valueInteger value="6"/>
              </answer>
            </item>
            <item>
              <linkId value="11300"/>
              <text value="Assoziiertes DCIS"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="149"/>
              <text value="DCIS Kerngrading"/>
              <answer>
                <valueString value="Intermediär (Grad 2)"/>
              </answer>
            </item>
            <item>
              <linkId value="150"/>
              <text value="DCIS Architektur"/>
              <answer>
                <valueString value="Kribriform"/>
              </answer>
            </item>
            <item>
              <linkId value="151"/>
              <text value="DCIS Nekrosen"/>
              <answer>
                <valueString value="Fokal (Komedo-Nekrosen)"/>
              </answer>
            </item>
            <item>
              <linkId value="11926"/>
              <text value="Tumorausdehnung"/>
              <answer>
                <valueString value="Auf Brustdrüse beschränkt"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.margins"/>
            <text value="Resektionsränder"/>
            <item>
              <linkId value="11470"/>
              <text value="RR-Status invasiv"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11490"/>
              <text value="Nächster tumorfreier RR"/>
              <answer>
                <valueString value="Posterior"/>
              </answer>
            </item>
            <item>
              <linkId value="11480"/>
              <text value="Mindestabstand invasiv"/>
              <answer>
                <valueQuantity>
                  <value value="5"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11968"/>
              <text value="RR-Status nichtinvasiv"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11970"/>
              <text value="Mindestabstand nichtinvasiv"/>
              <answer>
                <valueQuantity>
                  <value value="3"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.additional"/>
            <text value="Weitere Befunde"/>
            <item>
              <linkId value="11430"/>
              <text value="LVI"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="10880"/>
              <text value="Mikrokalzifikationen"/>
              <answer>
                <valueString value="In DCIS assoziiert"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.biomarkers"/>
            <text value="Biomarker"/>
            <item>
              <linkId value="11750"/>
              <text value="ER-Status"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11720"/>
              <text value="ER Prozent"/>
              <answer>
                <valueInteger value="90"/>
              </answer>
            </item>
            <item>
              <linkId value="11730"/>
              <text value="ER Färbeintensität"/>
              <answer>
                <valueString value="Stark"/>
              </answer>
            </item>
            <item>
              <linkId value="11790"/>
              <text value="PR-Status"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="52101004"/>
                  <display value="Present (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11760"/>
              <text value="PR Prozent"/>
              <answer>
                <valueInteger value="60"/>
              </answer>
            </item>
            <item>
              <linkId value="11770"/>
              <text value="PR Färbeintensität"/>
              <answer>
                <valueString value="Mäßig"/>
              </answer>
            </item>
            <item>
              <linkId value="11810"/>
              <text value="HER2-Score (IHC)"/>
              <answer>
                <valueString value="1+"/>
              </answer>
            </item>
            <item>
              <linkId value="11820"/>
              <text value="HER2-Amplifikation (ISH)"/>
              <answer>
                <valueString value="Nicht amplifiziert"/>
              </answer>
            </item>
            <item>
              <linkId value="11830"/>
              <text value="HER2-Gesamtstatus"/>
              <answer>
                <valueString value="Negativ"/>
              </answer>
            </item>
            <item>
              <linkId value="11840"/>
              <text value="Ki-67-Index"/>
              <answer>
                <valueInteger value="15"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.tnm"/>
            <text value="TNM"/>
            <item>
              <linkId value="169"/>
              <text value="pT-Kategorie"/>
              <answer>
                <valueString value="pT1c"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="bet.comment"/>
            <text value="Kommentar"/>
            <item>
              <linkId value="11900"/>
              <text value="Kommentar"/>
              <answer>
                <valueString
                             value="Korrelation mit dem Vorbefund der Stanzbiopsie (E_25_105): Übereinstimmende Histologie (invasives Mammakarzinom NST, G2). Biomarkerprofil bestätigt: ER+, PR+, HER2-, Luminal-A-like. Empfehlung: Tumorkonferenz zur weiteren Therapieplanung."/>
              </answer>
            </item>
          </item>
        </item>
      </QuestionnaireResponse>
    </resource>
  </entry>
  <entry>
    <fullUrl
             value="http://breastcancerspec.org/QuestionnaireResponse/IntegratedQRLymphNode"/>
    <resource>
      <QuestionnaireResponse>
        <id value="IntegratedQRLymphNode"/>
        <text>
          <status value="generated"/>
          <div xmlns="http://www.w3.org/1999/xhtml"><a name="QuestionnaireResponse_IntegratedQRLymphNode"> </a><p class="res-header-id"><b>Generated Narrative: QuestionnaireResponse IntegratedQRLymphNode</b></p><a name="IntegratedQRLymphNode"> </a><a name="hcIntegratedQRLymphNode"> </a><table border="1" cellpadding="0" cellspacing="0" style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 2px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="The linkID for the item">LinkID</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Text for the item">Text</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Minimum and Maximum # of times the item can appear in the instance">Definition</a></th><th style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px" class="hierarchy"><a href="https://hl7.org/fhir/R4/formats.html#table" title="The type of the item">Answer</a><span style="float: right"><a href="https://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_q_root.gif" alt="." style="background-color: white; background-color: inherit" title="QuestionnaireResponseRoot" class="hierarchy"/> IntegratedQRLymphNode</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Questionnaire:http://breastcancerspec.org/Questionnaire/OP_LN-Mamma</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> sln.root</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">SLN-Biopsie Axilla</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> sln.clinical</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Klinische Angaben</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11951</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Proben limitiert auswertbar</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/373067005">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11950</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">LK-Biopsie veranlassende klinische/bildgebende Befunde</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Invasives Mammakarzinom NST links, cN0</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11148</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Bildgebende Befunde</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Mammografie, Sonographie: Axilla klinisch unauffällig</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 10210</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Neoadjuvante Therapie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/373067005">SNOMED CT: 373067005</a> (No (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Group" class="hierarchy"/> sln.macro</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Makroskopie</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> sln.macro.sln1</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">SLN #1 Größe</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">12 x 8 x 6 mm, Patentblau-markiert</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> sln.macro.sln2</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">SLN #2 Größe</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">10 x 7 x 5 mm, Patentblau-markiert</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> sln.findings</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Axilläre Lymphknotenpräparate</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11540</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">LK OP Prozedur</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/396487001">SNOMED CT: 396487001</a> (Sentinel lymph node biopsy (procedure))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11620</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Seitenangabe</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/7771000">SNOMED CT: 7771000</a> (Left (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11630</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Anzahl der untersuchten (nonSLN)-axillären LK</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11640</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Anzahl der befallenen (nonSLN)-axillären LK</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11650</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Anzahl der untersuchten Sentinel-LK</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11660</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Anzahl der befallenen Sentinel-LK</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11944</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gesamtzahl untersuchter Lymphknoten</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">2</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11945</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gesamtzahl befallener Lymphknoten</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11947</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gesamtzahl makrometastatisch befallener Lymphknoten</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11948</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gesamtzahl mikrometastatisch befallener Lymphknoten</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11946</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Gesamtzahl ausschließlich ITC-befallener Lymphknoten</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0</td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: white; background-color: inherit" title="Item" class="hierarchy"/> 11690</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Ausdehnung der größten metastatischen Infiltration</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span>1.2 mm<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemm = 'mm')</span></span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 11700</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Extranodale Infiltration durch LK-Metastase</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span><span><a href="http://snomed.info/id/2667000">SNOMED CT: 2667000</a> (Absent (qualifier value))</span></span></td></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck001.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-group.png" alt="." style="background-color: white; background-color: inherit" title="Group" class="hierarchy"/> sln.tnm</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Pathologisches TNM-Staging</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 1px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0000.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon-q-string.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Item" class="hierarchy"/> 175</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Regionäre Lymphknoten (pN-Kategorie)</td><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 1px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">pN1mi(sn)</td></tr>
<tr><td colspan="4" class="hierarchy"><br/><a href="https://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="data:image/png;base64,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" alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
        </text>
        <questionnaire
                       value="http://breastcancerspec.org/Questionnaire/OP_LN-Mamma"/>
        <status value="completed"/>
        <subject>🔗 
          <reference value="Patient/Patient4"/>
        </subject>
        <authored value="2025-02-10T14:30:00+01:00"/>
        <author>🔗 
          <reference value="Practitioner/PathologistPractitioner"/>
        </author>
        <item>
          <linkId value="sln.root"/>
          <text value="SLN-Biopsie Axilla"/>
          <item>
            <linkId value="sln.clinical"/>
            <text value="Klinische Angaben"/>
            <item>
              <linkId value="11951"/>
              <text value="Proben limitiert auswertbar"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="373067005"/>
                  <display value="No (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11950"/>
              <text
                    value="LK-Biopsie veranlassende klinische/bildgebende Befunde"/>
              <answer>
                <valueString value="Invasives Mammakarzinom NST links, cN0"/>
              </answer>
            </item>
            <item>
              <linkId value="11148"/>
              <text value="Bildgebende Befunde"/>
              <answer>
                <valueString
                             value="Mammografie, Sonographie: Axilla klinisch unauffällig"/>
              </answer>
            </item>
            <item>
              <linkId value="10210"/>
              <text value="Neoadjuvante Therapie"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="373067005"/>
                  <display value="No (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="sln.macro"/>
            <text value="Makroskopie"/>
            <item>
              <linkId value="sln.macro.sln1"/>
              <text value="SLN #1 Größe"/>
              <answer>
                <valueString value="12 x 8 x 6 mm, Patentblau-markiert"/>
              </answer>
            </item>
            <item>
              <linkId value="sln.macro.sln2"/>
              <text value="SLN #2 Größe"/>
              <answer>
                <valueString value="10 x 7 x 5 mm, Patentblau-markiert"/>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="sln.findings"/>
            <text value="Axilläre Lymphknotenpräparate"/>
            <item>
              <linkId value="11540"/>
              <text value="LK OP Prozedur"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="396487001"/>
                  <display value="Sentinel lymph node biopsy (procedure)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11620"/>
              <text value="Seitenangabe"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="7771000"/>
                  <display value="Left (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
            <item>
              <linkId value="11630"/>
              <text value="Anzahl der untersuchten (nonSLN)-axillären LK"/>
              <answer>
                <valueInteger value="0"/>
              </answer>
            </item>
            <item>
              <linkId value="11640"/>
              <text value="Anzahl der befallenen (nonSLN)-axillären LK"/>
              <answer>
                <valueInteger value="0"/>
              </answer>
            </item>
            <item>
              <linkId value="11650"/>
              <text value="Anzahl der untersuchten Sentinel-LK"/>
              <answer>
                <valueInteger value="2"/>
              </answer>
            </item>
            <item>
              <linkId value="11660"/>
              <text value="Anzahl der befallenen Sentinel-LK"/>
              <answer>
                <valueInteger value="1"/>
              </answer>
            </item>
            <item>
              <linkId value="11944"/>
              <text value="Gesamtzahl untersuchter Lymphknoten"/>
              <answer>
                <valueInteger value="2"/>
              </answer>
            </item>
            <item>
              <linkId value="11945"/>
              <text value="Gesamtzahl befallener Lymphknoten"/>
              <answer>
                <valueInteger value="1"/>
              </answer>
            </item>
            <item>
              <linkId value="11947"/>
              <text
                    value="Gesamtzahl makrometastatisch befallener Lymphknoten"/>
              <answer>
                <valueInteger value="0"/>
              </answer>
            </item>
            <item>
              <linkId value="11948"/>
              <text
                    value="Gesamtzahl mikrometastatisch befallener Lymphknoten"/>
              <answer>
                <valueInteger value="1"/>
              </answer>
            </item>
            <item>
              <linkId value="11946"/>
              <text
                    value="Gesamtzahl ausschließlich ITC-befallener Lymphknoten"/>
              <answer>
                <valueInteger value="0"/>
              </answer>
            </item>
            <item>
              <linkId value="11690"/>
              <text
                    value="Ausdehnung der größten metastatischen Infiltration"/>
              <answer>
                <valueQuantity>
                  <value value="1.2"/>
                  <unit value="mm"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mm"/>
                </valueQuantity>
              </answer>
            </item>
            <item>
              <linkId value="11700"/>
              <text value="Extranodale Infiltration durch LK-Metastase"/>
              <answer>
                <valueCoding>
                  <system value="http://snomed.info/sct"/>
                  <code value="2667000"/>
                  <display value="Absent (qualifier value)"/>
                </valueCoding>
              </answer>
            </item>
          </item>
          <item>
            <linkId value="sln.tnm"/>
            <text value="Pathologisches TNM-Staging"/>
            <item>
              <linkId value="175"/>
              <text value="Regionäre Lymphknoten (pN-Kategorie)"/>
              <answer>
                <valueString value="pN1mi(sn)"/>
              </answer>
            </item>
          </item>
        </item>
      </QuestionnaireResponse>
    </resource>
  </entry>
</Bundle>