Name	Flags	Card.	Type	Description & Constraints
Condition		0..*	ConditionUvIps	Documentation of a health problem of the patient
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:age_at_diagnosis		0..1	CodeableConcept	Age at Diagnosis URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis Binding: Age at Diagnosis Value Set (extensible)
extension:age_at_onset		0..1	CodeableConcept	Age at Onset URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset Binding: Age at Onset Value Set (extensible)
clinicalStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition Clinical Status Codes (required)
verificationStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: ConditionVerificationStatus (required)
severity
coding		0..1	CodingIPS	A reference to a code defined by a terminology system
system		0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
code		0..1	code	Symbol in syntax defined by the system Binding: Severity Value Set (extensible)
bodySite	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text
coding		0..1	CodingIPS	A reference to a code defined by a terminology system
system		0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
subject		1..1	Reference(RareLink IPS Patient)	Who has the condition?
identifier	S	0..1	Identifier	Logical reference, when literal reference is not known
Slices for onset[x]		0..1	dateTime, Age, Period, Range, string	Estimated or actual date, date-time, or age Slice: Unordered, Open by type:$this
onset[x]:onsetDateTime		0..1	dateTime	Estimated or actual date, date-time, or age
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Condition.clinicalStatus	required	ConditionClinicalStatusCodes http://terminology.hl7.org/ValueSet/condition-clinical
Condition.verificationStatus	required	ConditionVerificationStatus http://terminology.hl7.org/ValueSet/condition-ver-status
Condition.severity.coding.code	extensible	SeverityVS https://rarelink.bih-charite.de/fhir/ValueSet/severity-vs from this IG

Name	Flags	Card.	Type	Description & Constraints
Condition	C	0..*	ConditionUvIps	Documentation of a health problem of the patient con-3: Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item con-4: If condition is abated, then clinicalStatus must be either inactive, resolved, or remission con-5: Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:age_at_diagnosis		0..1	CodeableConcept	Age at Diagnosis URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis Binding: Age at Diagnosis Value Set (extensible) ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:age_at_onset		0..1	CodeableConcept	Age at Onset URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset Binding: Age at Onset Value Set (extensible) ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
clinicalStatus	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition Clinical Status Codes (required) ele-1: All FHIR elements must have a @value or children
verificationStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: ConditionVerificationStatus (required) ele-1: All FHIR elements must have a @value or children
category	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problem Type - IPS (extensible) Additional Bindings Purpose Problem Type (LOINC) candidate ele-1: All FHIR elements must have a @value or children
severity	S	0..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition/DiagnosisSeverity (preferred) ele-1: All FHIR elements must have a @value or children
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system ele-1: All FHIR elements must have a @value or children
system	SΣ	0..1	uri	Identity of the terminology system ele-1: All FHIR elements must have a @value or children Required Pattern: http://snomed.info/sct
code	SΣ	0..1	code	Symbol in syntax defined by the system Binding: Severity Value Set (extensible) ele-1: All FHIR elements must have a @value or children
display	SΣ	0..1	string	Representation defined by the system ele-1: All FHIR elements must have a @value or children
Slices for extension				Content/Rules for all slices
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
text	SΣ	0..1	string	Plain text representation of the concept ele-1: All FHIR elements must have a @value or children
code	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problems - IPS (preferred): Code for a clinical problem (or absent/unknown problem) that is selected from SNOMED CT ele-1: All FHIR elements must have a @value or children
bodySite	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: SNOMEDCTBodyStructures (example) ele-1: All FHIR elements must have a @value or children
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system ele-1: All FHIR elements must have a @value or children
system	SΣ	0..1	uri	Identity of the terminology system ele-1: All FHIR elements must have a @value or children Required Pattern: http://snomed.info/sct
code	SΣ	0..1	code	Symbol in syntax defined by the system ele-1: All FHIR elements must have a @value or children
display	SΣ	0..1	string	Representation defined by the system ele-1: All FHIR elements must have a @value or children
Slices for extension				Content/Rules for all slices
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
text	SΣ	0..1	string	Plain text representation of the concept ele-1: All FHIR elements must have a @value or children
subject	SΣ	1..1	Reference(RareLink IPS Patient)	Who has the condition? ele-1: All FHIR elements must have a @value or children
reference	SΣC	1..1	string	Literal reference, Relative, internal or absolute URL ele-1: All FHIR elements must have a @value or children
identifier	SΣ	0..1	Identifier	Logical reference, when literal reference is not known ele-1: All FHIR elements must have a @value or children
Slices for onset[x]	SΣ	0..1		Estimated or actual date, date-time, or age Slice: Unordered, Open by type:$this ele-1: All FHIR elements must have a @value or children
onsetDateTime			dateTime
onset[x]:onsetDateTime	SΣ	0..1	dateTime	Estimated or actual date, date-time, or age ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Condition.clinicalStatus	required	ConditionClinicalStatusCodes http://terminology.hl7.org/ValueSet/condition-clinical
Condition.verificationStatus	required	ConditionVerificationStatus http://terminology.hl7.org/ValueSet/condition-ver-status
Condition.category	extensible	ProblemTypeUvIps http://hl7.org/fhir/uv/ips/ValueSet/problem-type-uv-ips
Condition.severity	preferred	Condition/DiagnosisSeverity http://hl7.org/fhir/ValueSet/condition-severity from the FHIR Standard
Condition.severity.coding.code	extensible	SeverityVS https://rarelink.bih-charite.de/fhir/ValueSet/severity-vs from this IG
Condition.code	preferred	ProblemsUvIps http://hl7.org/fhir/uv/ips/ValueSet/problems-uv-ips
Condition.bodySite	example	SNOMEDCTBodyStructures http://hl7.org/fhir/ValueSet/body-site from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
con-3	best practice	Condition	Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item : clinicalStatus.exists() or verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code = 'entered-in-error').exists() or category.select($this='problem-list-item').empty()
con-4	error	Condition	If condition is abated, then clinicalStatus must be either inactive, resolved, or remission : abatement.empty() or clinicalStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-clinical' and (code='resolved' or code='remission' or code='inactive')).exists()
con-5	error	Condition	Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code='entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	Condition	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Condition	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Condition	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Condition	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Condition	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
Condition	C	0..*	ConditionUvIps	Documentation of a health problem of the patient con-3: Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item con-4: If condition is abated, then clinicalStatus must be either inactive, resolved, or remission con-5: Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:age_at_diagnosis		0..1	CodeableConcept	Age at Diagnosis URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis Binding: Age at Diagnosis Value Set (extensible)
extension:age_at_onset		0..1	CodeableConcept	Age at Onset URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset Binding: Age at Onset Value Set (extensible)
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External Ids for this condition
clinicalStatus	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition Clinical Status Codes (required)
verificationStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: ConditionVerificationStatus (required)
category	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problem Type - IPS (extensible) Additional Bindings Purpose Problem Type (LOINC) candidate
severity	S	0..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition/DiagnosisSeverity (preferred)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	0..1	code	Symbol in syntax defined by the system Binding: Severity Value Set (extensible)
display	SΣ	0..1	string	Representation defined by the system
id		0..1	string	xml:id (or equivalent in JSON)
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation
value		0..1	string	Primitive value for string Max Length:1048576
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	SΣ	0..1	string	Plain text representation of the concept
code	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problems - IPS (preferred): Code for a clinical problem (or absent/unknown problem) that is selected from SNOMED CT
bodySite	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: SNOMEDCTBodyStructures (example)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	0..1	code	Symbol in syntax defined by the system
display	SΣ	0..1	string	Representation defined by the system
id		0..1	string	xml:id (or equivalent in JSON)
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation
value		0..1	string	Primitive value for string Max Length:1048576
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	SΣ	0..1	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(RareLink IPS Patient)	Who has the condition?
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
reference	SΣC	1..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	SΣ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
encounter	Σ	0..1	Reference(Encounter)	Encounter created as part of
Slices for onset[x]	SΣ	0..1		Estimated or actual date, date-time, or age Slice: Unordered, Open by type:$this
onsetDateTime			dateTime S
onsetAge			Age
onsetPeriod			Period
onsetRange			Range
onsetString			string
onset[x]:onsetDateTime	SΣ	0..1	dateTime S	Estimated or actual date, date-time, or age
abatement[x]	C	0..1		When in resolution/remission
abatementDateTime			dateTime
abatementAge			Age
abatementPeriod			Period
abatementRange			Range
abatementString			string
recordedDate	Σ	0..1	dateTime	Date record was first recorded
recorder	Σ	0..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson)	Who recorded the condition
asserter	Σ	0..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson)	Person who asserts this condition
stage	C	0..*	BackboneElement	Stage/grade, usually assessed formally con-1: Stage SHALL have summary or assessment
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
summary	C	0..1	CodeableConcept	Simple summary (disease specific) Binding: ConditionStage (example): Codes describing condition stages (e.g. Cancer stages).
assessment	C	0..*	Reference(ClinicalImpression | DiagnosticReport | Observation)	Formal record of assessment
type		0..1	CodeableConcept	Kind of staging Binding: ConditionStageType (example): Codes describing the kind of condition staging (e.g. clinical or pathological).
evidence	C	0..*	BackboneElement	Supporting evidence con-2: evidence SHALL have code or details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	ΣC	0..*	CodeableConcept	Manifestation/symptom Binding: ManifestationAndSymptomCodes (example): Codes that describe the manifestation or symptoms of a condition.
detail	ΣC	0..*	Reference(Resource)	Supporting information found elsewhere
note		0..*	Annotation	Additional information about the Condition
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Condition.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Condition.clinicalStatus	required	ConditionClinicalStatusCodes http://terminology.hl7.org/ValueSet/condition-clinical
Condition.verificationStatus	required	ConditionVerificationStatus http://terminology.hl7.org/ValueSet/condition-ver-status
Condition.category	extensible	ProblemTypeUvIps http://hl7.org/fhir/uv/ips/ValueSet/problem-type-uv-ips
Condition.severity	preferred	Condition/DiagnosisSeverity http://hl7.org/fhir/ValueSet/condition-severity from the FHIR Standard
Condition.severity.coding.code	extensible	SeverityVS https://rarelink.bih-charite.de/fhir/ValueSet/severity-vs from this IG
Condition.code	preferred	ProblemsUvIps http://hl7.org/fhir/uv/ips/ValueSet/problems-uv-ips
Condition.bodySite	example	SNOMEDCTBodyStructures http://hl7.org/fhir/ValueSet/body-site from the FHIR Standard
Condition.subject.type	extensible	ResourceType http://hl7.org/fhir/ValueSet/resource-types from the FHIR Standard
Condition.stage.summary	example	ConditionStage http://hl7.org/fhir/ValueSet/condition-stage from the FHIR Standard
Condition.stage.type	example	ConditionStageType http://hl7.org/fhir/ValueSet/condition-stage-type from the FHIR Standard
Condition.evidence.code	example	ManifestationAndSymptomCodes http://hl7.org/fhir/ValueSet/manifestation-or-symptom from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
con-1	error	Condition.stage	Stage SHALL have summary or assessment : summary.exists() or assessment.exists()
con-2	error	Condition.evidence	evidence SHALL have code or details : code.exists() or detail.exists()
con-3	best practice	Condition	Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item : clinicalStatus.exists() or verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code = 'entered-in-error').exists() or category.select($this='problem-list-item').empty()
con-4	error	Condition	If condition is abated, then clinicalStatus must be either inactive, resolved, or remission : abatement.empty() or clinicalStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-clinical' and (code='resolved' or code='remission' or code='inactive')).exists()
con-5	error	Condition	Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code='entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	Condition	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Condition	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Condition	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Condition	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Condition	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Summary

Mandatory: 2 elements
Must-Support: 2 elements

Structures

This structure refers to these other structures:

• RareLink IPS Patient (https://rarelink.bih-charite.de/fhir/StructureDefinition/rarelink-ips-patient)

Extensions

This structure refers to these extensions:

• https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis
• https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Condition.onset[x]

Name	Flags	Card.	Type	Description & Constraints
Condition		0..*	ConditionUvIps	Documentation of a health problem of the patient
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:age_at_diagnosis		0..1	CodeableConcept	Age at Diagnosis URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis Binding: Age at Diagnosis Value Set (extensible)
extension:age_at_onset		0..1	CodeableConcept	Age at Onset URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset Binding: Age at Onset Value Set (extensible)
clinicalStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition Clinical Status Codes (required)
verificationStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: ConditionVerificationStatus (required)
severity
coding		0..1	CodingIPS	A reference to a code defined by a terminology system
system		0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
code		0..1	code	Symbol in syntax defined by the system Binding: Severity Value Set (extensible)
bodySite	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text
coding		0..1	CodingIPS	A reference to a code defined by a terminology system
system		0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
subject		1..1	Reference(RareLink IPS Patient)	Who has the condition?
identifier	S	0..1	Identifier	Logical reference, when literal reference is not known
Slices for onset[x]		0..1	dateTime, Age, Period, Range, string	Estimated or actual date, date-time, or age Slice: Unordered, Open by type:$this
onset[x]:onsetDateTime		0..1	dateTime	Estimated or actual date, date-time, or age
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Condition.clinicalStatus	required	ConditionClinicalStatusCodes http://terminology.hl7.org/ValueSet/condition-clinical
Condition.verificationStatus	required	ConditionVerificationStatus http://terminology.hl7.org/ValueSet/condition-ver-status
Condition.severity.coding.code	extensible	SeverityVS https://rarelink.bih-charite.de/fhir/ValueSet/severity-vs from this IG

Name	Flags	Card.	Type	Description & Constraints
Condition	C	0..*	ConditionUvIps	Documentation of a health problem of the patient con-3: Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item con-4: If condition is abated, then clinicalStatus must be either inactive, resolved, or remission con-5: Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:age_at_diagnosis		0..1	CodeableConcept	Age at Diagnosis URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis Binding: Age at Diagnosis Value Set (extensible) ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:age_at_onset		0..1	CodeableConcept	Age at Onset URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset Binding: Age at Onset Value Set (extensible) ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
clinicalStatus	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition Clinical Status Codes (required) ele-1: All FHIR elements must have a @value or children
verificationStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: ConditionVerificationStatus (required) ele-1: All FHIR elements must have a @value or children
category	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problem Type - IPS (extensible) Additional Bindings Purpose Problem Type (LOINC) candidate ele-1: All FHIR elements must have a @value or children
severity	S	0..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition/DiagnosisSeverity (preferred) ele-1: All FHIR elements must have a @value or children
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system ele-1: All FHIR elements must have a @value or children
system	SΣ	0..1	uri	Identity of the terminology system ele-1: All FHIR elements must have a @value or children Required Pattern: http://snomed.info/sct
code	SΣ	0..1	code	Symbol in syntax defined by the system Binding: Severity Value Set (extensible) ele-1: All FHIR elements must have a @value or children
display	SΣ	0..1	string	Representation defined by the system ele-1: All FHIR elements must have a @value or children
Slices for extension				Content/Rules for all slices
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
text	SΣ	0..1	string	Plain text representation of the concept ele-1: All FHIR elements must have a @value or children
code	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problems - IPS (preferred): Code for a clinical problem (or absent/unknown problem) that is selected from SNOMED CT ele-1: All FHIR elements must have a @value or children
bodySite	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: SNOMEDCTBodyStructures (example) ele-1: All FHIR elements must have a @value or children
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system ele-1: All FHIR elements must have a @value or children
system	SΣ	0..1	uri	Identity of the terminology system ele-1: All FHIR elements must have a @value or children Required Pattern: http://snomed.info/sct
code	SΣ	0..1	code	Symbol in syntax defined by the system ele-1: All FHIR elements must have a @value or children
display	SΣ	0..1	string	Representation defined by the system ele-1: All FHIR elements must have a @value or children
Slices for extension				Content/Rules for all slices
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
text	SΣ	0..1	string	Plain text representation of the concept ele-1: All FHIR elements must have a @value or children
subject	SΣ	1..1	Reference(RareLink IPS Patient)	Who has the condition? ele-1: All FHIR elements must have a @value or children
reference	SΣC	1..1	string	Literal reference, Relative, internal or absolute URL ele-1: All FHIR elements must have a @value or children
identifier	SΣ	0..1	Identifier	Logical reference, when literal reference is not known ele-1: All FHIR elements must have a @value or children
Slices for onset[x]	SΣ	0..1		Estimated or actual date, date-time, or age Slice: Unordered, Open by type:$this ele-1: All FHIR elements must have a @value or children
onsetDateTime			dateTime
onset[x]:onsetDateTime	SΣ	0..1	dateTime	Estimated or actual date, date-time, or age ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Condition.clinicalStatus	required	ConditionClinicalStatusCodes http://terminology.hl7.org/ValueSet/condition-clinical
Condition.verificationStatus	required	ConditionVerificationStatus http://terminology.hl7.org/ValueSet/condition-ver-status
Condition.category	extensible	ProblemTypeUvIps http://hl7.org/fhir/uv/ips/ValueSet/problem-type-uv-ips
Condition.severity	preferred	Condition/DiagnosisSeverity http://hl7.org/fhir/ValueSet/condition-severity from the FHIR Standard
Condition.severity.coding.code	extensible	SeverityVS https://rarelink.bih-charite.de/fhir/ValueSet/severity-vs from this IG
Condition.code	preferred	ProblemsUvIps http://hl7.org/fhir/uv/ips/ValueSet/problems-uv-ips
Condition.bodySite	example	SNOMEDCTBodyStructures http://hl7.org/fhir/ValueSet/body-site from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
con-3	best practice	Condition	Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item : clinicalStatus.exists() or verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code = 'entered-in-error').exists() or category.select($this='problem-list-item').empty()
con-4	error	Condition	If condition is abated, then clinicalStatus must be either inactive, resolved, or remission : abatement.empty() or clinicalStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-clinical' and (code='resolved' or code='remission' or code='inactive')).exists()
con-5	error	Condition	Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code='entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	Condition	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Condition	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Condition	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Condition	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Condition	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
Condition	C	0..*	ConditionUvIps	Documentation of a health problem of the patient con-3: Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item con-4: If condition is abated, then clinicalStatus must be either inactive, resolved, or remission con-5: Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:age_at_diagnosis		0..1	CodeableConcept	Age at Diagnosis URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis Binding: Age at Diagnosis Value Set (extensible)
extension:age_at_onset		0..1	CodeableConcept	Age at Onset URL: https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset Binding: Age at Onset Value Set (extensible)
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External Ids for this condition
clinicalStatus	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition Clinical Status Codes (required)
verificationStatus		1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: ConditionVerificationStatus (required)
category	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problem Type - IPS (extensible) Additional Bindings Purpose Problem Type (LOINC) candidate
severity	S	0..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Condition/DiagnosisSeverity (preferred)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	0..1	code	Symbol in syntax defined by the system Binding: Severity Value Set (extensible)
display	SΣ	0..1	string	Representation defined by the system
id		0..1	string	xml:id (or equivalent in JSON)
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation
value		0..1	string	Primitive value for string Max Length:1048576
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	SΣ	0..1	string	Plain text representation of the concept
code	S	1..1	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: Problems - IPS (preferred): Code for a clinical problem (or absent/unknown problem) that is selected from SNOMED CT
bodySite	S	0..*	CodeableConceptIPS	Concept - reference to a terminology or just text Binding: SNOMEDCTBodyStructures (example)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	S	0..1	CodingIPS	A reference to a code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	0..1	code	Symbol in syntax defined by the system
display	SΣ	0..1	string	Representation defined by the system
id		0..1	string	xml:id (or equivalent in JSON)
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:translation		0..*	(Complex)	Language Translation (Localization) URL: http://hl7.org/fhir/StructureDefinition/translation
value		0..1	string	Primitive value for string Max Length:1048576
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	SΣ	0..1	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(RareLink IPS Patient)	Who has the condition?
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
reference	SΣC	1..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	SΣ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
encounter	Σ	0..1	Reference(Encounter)	Encounter created as part of
Slices for onset[x]	SΣ	0..1		Estimated or actual date, date-time, or age Slice: Unordered, Open by type:$this
onsetDateTime			dateTime S
onsetAge			Age
onsetPeriod			Period
onsetRange			Range
onsetString			string
onset[x]:onsetDateTime	SΣ	0..1	dateTime S	Estimated or actual date, date-time, or age
abatement[x]	C	0..1		When in resolution/remission
abatementDateTime			dateTime
abatementAge			Age
abatementPeriod			Period
abatementRange			Range
abatementString			string
recordedDate	Σ	0..1	dateTime	Date record was first recorded
recorder	Σ	0..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson)	Who recorded the condition
asserter	Σ	0..1	Reference(Practitioner | PractitionerRole | Patient | RelatedPerson)	Person who asserts this condition
stage	C	0..*	BackboneElement	Stage/grade, usually assessed formally con-1: Stage SHALL have summary or assessment
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
summary	C	0..1	CodeableConcept	Simple summary (disease specific) Binding: ConditionStage (example): Codes describing condition stages (e.g. Cancer stages).
assessment	C	0..*	Reference(ClinicalImpression | DiagnosticReport | Observation)	Formal record of assessment
type		0..1	CodeableConcept	Kind of staging Binding: ConditionStageType (example): Codes describing the kind of condition staging (e.g. clinical or pathological).
evidence	C	0..*	BackboneElement	Supporting evidence con-2: evidence SHALL have code or details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	ΣC	0..*	CodeableConcept	Manifestation/symptom Binding: ManifestationAndSymptomCodes (example): Codes that describe the manifestation or symptoms of a condition.
detail	ΣC	0..*	Reference(Resource)	Supporting information found elsewhere
note		0..*	Annotation	Additional information about the Condition
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
Condition.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Condition.clinicalStatus	required	ConditionClinicalStatusCodes http://terminology.hl7.org/ValueSet/condition-clinical
Condition.verificationStatus	required	ConditionVerificationStatus http://terminology.hl7.org/ValueSet/condition-ver-status
Condition.category	extensible	ProblemTypeUvIps http://hl7.org/fhir/uv/ips/ValueSet/problem-type-uv-ips
Condition.severity	preferred	Condition/DiagnosisSeverity http://hl7.org/fhir/ValueSet/condition-severity from the FHIR Standard
Condition.severity.coding.code	extensible	SeverityVS https://rarelink.bih-charite.de/fhir/ValueSet/severity-vs from this IG
Condition.code	preferred	ProblemsUvIps http://hl7.org/fhir/uv/ips/ValueSet/problems-uv-ips
Condition.bodySite	example	SNOMEDCTBodyStructures http://hl7.org/fhir/ValueSet/body-site from the FHIR Standard
Condition.subject.type	extensible	ResourceType http://hl7.org/fhir/ValueSet/resource-types from the FHIR Standard
Condition.stage.summary	example	ConditionStage http://hl7.org/fhir/ValueSet/condition-stage from the FHIR Standard
Condition.stage.type	example	ConditionStageType http://hl7.org/fhir/ValueSet/condition-stage-type from the FHIR Standard
Condition.evidence.code	example	ManifestationAndSymptomCodes http://hl7.org/fhir/ValueSet/manifestation-or-symptom from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
con-1	error	Condition.stage	Stage SHALL have summary or assessment : summary.exists() or assessment.exists()
con-2	error	Condition.evidence	evidence SHALL have code or details : code.exists() or detail.exists()
con-3	best practice	Condition	Condition.clinicalStatus SHALL be present if verificationStatus is not entered-in-error and category is problem-list-item : clinicalStatus.exists() or verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code = 'entered-in-error').exists() or category.select($this='problem-list-item').empty()
con-4	error	Condition	If condition is abated, then clinicalStatus must be either inactive, resolved, or remission : abatement.empty() or clinicalStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-clinical' and (code='resolved' or code='remission' or code='inactive')).exists()
con-5	error	Condition	Condition.clinicalStatus SHALL NOT be present if verification Status is entered-in-error : verificationStatus.coding.where(system='http://terminology.hl7.org/CodeSystem/condition-ver-status' and code='entered-in-error').empty() or clinicalStatus.empty()
dom-2	error	Condition	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Condition	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Condition	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Condition	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Condition	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Summary

Mandatory: 2 elements
Must-Support: 2 elements

Structures

This structure refers to these other structures:

• RareLink IPS Patient (https://rarelink.bih-charite.de/fhir/StructureDefinition/rarelink-ips-patient)

Extensions

This structure refers to these extensions:

• https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-diagnosis
• https://rarelink.bih-charite.de/fhir/StructureDefinition/age-at-onset

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Condition.onset[x]