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: Fall 10: PD-L1 Status — CPS 25, positiv (SP142) - JSON Representation

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{
  "resourceType" : "Observation",
  "id" : "Fall10-PDL1-Status",
  "meta" : {
    "profile" : [
      🔗 "https://www.senologie.org/fhir/StructureDefinition/senologie-pdl1-status"
    ]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation Fall10-PDL1-Status</b></p><a name=\"Fall10-PDL1-Status\"> </a><a name=\"hcFall10-PDL1-Status\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-senologie-pdl1-status.html\">BIH Senologie PD-L1 Status</a></p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span>, <span title=\"Codes:{http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs biomarker-category}\">A characterization of a given biomarker observation.</span></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 1234806008}\">PD-L1 Immunhistochemie</span></p><p><b>subject</b>: <a href=\"Patient-Fall10-Patient-Christina-Becker.html\">Christina Becker  Female, DoB: 1982-12-14 ( http://fhir.bih-charite.de/sid/patient-id#SENO-2025-010)</a></p><p><b>effective</b>: 2025-06-05</p><p><b>method</b>: <span title=\"Codes:\">PD-L1 IHC SP142 (Ventana/Roche)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html C176582}\">PD-L1 Combined Positive Score</span></p><p><b>value</b>: 25 score<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{score} = '{score}')</span></p><p><b>interpretation</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation POS}\">Positive</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html C199175}\">Cells.programmed cell death ligand 1/Viable tumor cells in Tissue by Immune stain</span></p><p><b>value</b>: 5 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>interpretation</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation POS}\">Positive</span></p></blockquote></div>"
  },
  "status" : "final",
  "category" : [
    {
      "coding" : [
        {
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }
      ]
    },
    {
      "coding" : [
        {
          "system" : "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
          "code" : "biomarker-category"
        }
      ]
    }
  ],
  "code" : {
    "coding" : [
      {
        "system" : "http://snomed.info/sct",
        "code" : "1234806008",
        "display" : "Observation using immunohistochemistry (observable entity)"
      }
    ],
    "text" : "PD-L1 Immunhistochemie"
  },
  "subject" : {
    🔗 "reference" : "Patient/Fall10-Patient-Christina-Becker"
  },
  "effectiveDateTime" : "2025-06-05",
  "method" : {
    "text" : "PD-L1 IHC SP142 (Ventana/Roche)"
  },
  "component" : [
    {
      "code" : {
        "coding" : [
          {
            "system" : "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
            "code" : "C176582",
            "display" : "PD-L1 Combined Positive Score"
          }
        ]
      },
      "valueQuantity" : {
        "value" : 25,
        "unit" : "score",
        "system" : "http://unitsofmeasure.org",
        "code" : "{score}"
      },
      "interpretation" : [
        {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
              "code" : "POS",
              "display" : "Positive"
            }
          ]
        }
      ]
    },
    {
      "code" : {
        "coding" : [
          {
            "system" : "https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html",
            "code" : "C199175",
            "display" : "Cells.programmed cell death ligand 1/Viable tumor cells in Tissue by Immune stain"
          }
        ]
      },
      "valueQuantity" : {
        "value" : 5,
        "unit" : "%",
        "system" : "http://unitsofmeasure.org",
        "code" : "%"
      },
      "interpretation" : [
        {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
              "code" : "POS",
              "display" : "Positive"
            }
          ]
        }
      ]
    }
  ]
}